Ye Xu

Xu Ye, Meng Xiao, Zhiyuan Ning et al.

With the development of natural language processing techniques(NLP), automatic diagnosis of eye diseases using ophthalmology electronic medical records (OEMR) has become possible. It aims to evaluate the condition of both eyes of a patient respectively, and we formulate it as a particular multi-label classification task in this paper. Although there are a few related studies in other diseases, automatic diagnosis of eye diseases exhibits unique characteristics. First, descriptions of both eyes are mixed up in OEMR documents, with both free text and templated asymptomatic descriptions, resulting in sparsity and clutter of information. Second, OEMR documents contain multiple parts of descriptions and have long document lengths. Third, it is critical to provide explainability to the disease diagnosis model. To overcome those challenges, we present an effective automatic eye disease diagnosis framework, NEEDED. In this framework, a preprocessing module is integrated to improve the density and quality of information. Then, we design a hierarchical transformer structure for learning the contextualized representations of each sentence in the OEMR document. For the diagnosis part, we propose an attention-based predictor that enables traceable diagnosis by obtaining disease-specific information. Experiments on the real dataset and comparison with several baseline models show the advantage and explainability of our framework.

Daniel Nemirovsky, Nicolas Thiebaut, Ye Xu et al.

The prevalence of machine learning models in various industries has led to growing demands for model interpretability and for the ability to provide meaningful recourse to users. For example, patients hoping to improve their diagnoses or loan applicants seeking to increase their chances of approval. Counterfactuals can help in this regard by identifying input perturbations that would result in more desirable prediction outcomes. Meaningful counterfactuals should be able to achieve the desired outcome, but also be realistic, actionable, and efficient to compute. Current approaches achieve desired outcomes with moderate actionability but are severely limited in terms of realism and latency. To tackle these limitations, we apply Generative Adversarial Nets (GANs) toward counterfactual search. We also introduce a novel Residual GAN (RGAN) that helps to improve counterfactual realism and actionability compared to regular GANs. The proposed CounteRGAN method utilizes an RGAN and a target classifier to produce counterfactuals capable of providing meaningful recourse. Evaluations on two popular datasets highlight how the CounteRGAN is able to overcome the limitations of existing methods, including latency improvements of >50x to >90,000x, making meaningful recourse available in real-time and applicable to a wide range of domains.