Sylvain V. Costes

Sylvain V. Costes, Sergio Garcia Busto, Ryan T. Scott et al.

While AI holds the potential to revolutionize space life sciences, realizing this promise is contingent upon the systematic restructuring of heterogeneous spaceflight biological data into machine-actionable, AI-ready forms. Even though open access principles support human reuse and scientific reproducibility, this does not necessarily enable AI systems to access and analyze such a diverse set of scientific datasets. In addition, the growing array of AI approaches places distinct demands on data structure, metadata, and access interfaces. In order to respond to such growing changes we propose a three-tier approach, proceeding from FAIR to AI-ready to space-ready data. We discuss existing infrastructures and how they can be improved to close the AI access gap. We conclude by proposing a neutral international coordinating body as the governance backbone for the trustworthy, agent-accessible space biology infrastructure that deep space biological research will require.

Bishwaranjan Bhattacharjee, Aashka Trivedi, Masayasu Muraoka et al.

Large language models (LLMs) trained on general domain corpora showed remarkable results on natural language processing (NLP) tasks. However, previous research demonstrated LLMs trained using domain-focused corpora perform better on specialized tasks. Inspired by this insight, we developed INDUS, a comprehensive suite of LLMs tailored for the closely-related domains of Earth science, biology, physics, heliophysics, planetary sciences and astrophysics, and trained using curated scientific corpora drawn from diverse data sources. The suite of models include: (1) an encoder model trained using domain-specific vocabulary and corpora to address NLP tasks, (2) a contrastive-learning based text embedding model trained using a diverse set of datasets to address information retrieval tasks and (3) smaller versions of these models created using knowledge distillation for applications which have latency or resource constraints. We also created three new scientific benchmark datasets, CLIMATE-CHANGE NER (entity-recognition), NASA-QA (extractive QA) and NASA-IR (IR) to accelerate research in these multi-disciplinary fields. We show that our models outperform both general-purpose (RoBERTa) and domain-specific (SCIBERT) encoders on these new tasks as well as existing tasks in the domains of interest. Furthermore, we demonstrate the use of these models in two industrial settings -- as a retrieval model for large-scale vector search applications and in automatic content tagging systems.

Ryan T. Scott, Erik L. Antonsen, Lauren M. Sanders et al.

Human space exploration beyond low Earth orbit will involve missions of significant distance and duration. To effectively mitigate myriad space health hazards, paradigm shifts in data and space health systems are necessary to enable Earth-independence, rather than Earth-reliance. Promising developments in the fields of artificial intelligence and machine learning for biology and health can address these needs. We propose an appropriately autonomous and intelligent Precision Space Health system that will monitor, aggregate, and assess biomedical statuses; analyze and predict personalized adverse health outcomes; adapt and respond to newly accumulated data; and provide preventive, actionable, and timely insights to individual deep space crew members and iterative decision support to their crew medical officer. Here we present a summary of recommendations from a workshop organized by the National Aeronautics and Space Administration, on future applications of artificial intelligence in space biology and health. In the next decade, biomonitoring technology, biomarker science, spacecraft hardware, intelligent software, and streamlined data management must mature and be woven together into a Precision Space Health system to enable humanity to thrive in deep space.

Lauren M. Sanders, Jason H. Yang, Ryan T. Scott et al.

Space biology research aims to understand fundamental effects of spaceflight on organisms, develop foundational knowledge to support deep space exploration, and ultimately bioengineer spacecraft and habitats to stabilize the ecosystem of plants, crops, microbes, animals, and humans for sustained multi-planetary life. To advance these aims, the field leverages experiments, platforms, data, and model organisms from both spaceborne and ground-analog studies. As research is extended beyond low Earth orbit, experiments and platforms must be maximally autonomous, light, agile, and intelligent to expedite knowledge discovery. Here we present a summary of recommendations from a workshop organized by the National Aeronautics and Space Administration on artificial intelligence, machine learning, and modeling applications which offer key solutions toward these space biology challenges. In the next decade, the synthesis of artificial intelligence into the field of space biology will deepen the biological understanding of spaceflight effects, facilitate predictive modeling and analytics, support maximally autonomous and reproducible experiments, and efficiently manage spaceborne data and metadata, all with the goal to enable life to thrive in deep space.