Zhijie Wen

Hao Zhang, Qi Wang, Jun Shi et al.

Multi-modal Magnetic Resonance Imaging (MRI) offers complementary diagnostic information, but some modalities are limited by the long scanning time. To accelerate the whole acquisition process, MRI reconstruction of one modality from highly undersampled k-space data with another fully-sampled reference modality is an efficient solution. However, the misalignment between modalities, which is common in clinic practice, can negatively affect reconstruction quality. Existing deep learning-based methods that account for inter-modality misalignment perform better, but still share two main common limitations: (1) The spatial alignment task is not adaptively integrated with the reconstruction process, resulting in insufficient complementarity between the two tasks; (2) the entire framework has weak interpretability. In this paper, we construct a novel Deep Unfolding Network with Spatial Alignment, termed DUN-SA, to appropriately embed the spatial alignment task into the reconstruction process. Concretely, we derive a novel joint alignment-reconstruction model with a specially designed cross-modal spatial alignment term. By relaxing the model into cross-modal spatial alignment and multi-modal reconstruction tasks, we propose an effective algorithm to solve this model alternatively. Then, we unfold the iterative steps of the proposed algorithm and design corresponding network modules to build DUN-SA with interpretability. Through end-to-end training, we effectively compensate for spatial misalignment using only reconstruction loss, and utilize the progressively aligned reference modality to provide inter-modality prior to improve the reconstruction of the target modality. Comprehensive experiments on three real datasets demonstrate that our method exhibits superior reconstruction performance compared to state-of-the-art methods.

Hao Zhang, Qi Wang, Jian Sun et al.

Magnetic Resonance Imaging (MRI) is widely used in clinical practice, but suffered from prolonged acquisition time. Although deep learning methods have been proposed to accelerate acquisition and demonstrate promising performance, they rely on high-quality fully-sampled datasets for training in a supervised manner. However, such datasets are time-consuming and expensive-to-collect, which constrains their broader applications. On the other hand, self-supervised methods offer an alternative by enabling learning from under-sampled data alone, but most existing methods rely on further partitioned under-sampled k-space data as model's input for training, resulting in a loss of valuable information. Additionally, their models have not fully incorporated image priors, leading to degraded reconstruction performance. In this paper, we propose a novel re-visible dual-domain self-supervised deep unfolding network to address these issues when only under-sampled datasets are available. Specifically, by incorporating re-visible dual-domain loss, all under-sampled k-space data are utilized during training to mitigate information loss caused by further partitioning. This design enables the model to implicitly adapt to all under-sampled k-space data as input. Additionally, we design a deep unfolding network based on Chambolle and Pock Proximal Point Algorithm (DUN-CP-PPA) to achieve end-to-end reconstruction, incorporating imaging physics and image priors to guide the reconstruction process. By employing a Spatial-Frequency Feature Extraction (SFFE) block to capture global and local feature representation, we enhance the model's efficiency to learn comprehensive image priors. Experiments conducted on the fastMRI and IXI datasets demonstrate that our method significantly outperforms state-of-the-art approaches in terms of reconstruction performance.