Hanyu Zheng

Quan Liu, Hanyu Zheng, Brandon T. Swartz et al.

Deep neural networks (DNNs) utilized recently are physically deployed with computational units (e.g., CPUs and GPUs). Such a design might lead to a heavy computational burden, significant latency, and intensive power consumption, which are critical limitations in applications such as the Internet of Things (IoT), edge computing, and the usage of drones. Recent advances in optical computational units (e.g., metamaterial) have shed light on energy-free and light-speed neural networks. However, the digital design of the metamaterial neural network (MNN) is fundamentally limited by its physical limitations, such as precision, noise, and bandwidth during fabrication. Moreover, the unique advantages of MNN's (e.g., light-speed computation) are not fully explored via standard 3x3 convolution kernels. In this paper, we propose a novel large kernel metamaterial neural network (LMNN) that maximizes the digital capacity of the state-of-the-art (SOTA) MNN with model re-parametrization and network compression, while also considering the optical limitation explicitly. The new digital learning scheme can maximize the learning capacity of MNN while modeling the physical restrictions of meta-optic. With the proposed LMNN, the computation cost of the convolutional front-end can be offloaded into fabricated optical hardware. The experimental results on two publicly available datasets demonstrate that the optimized hybrid design improved classification accuracy while reducing computational latency. The development of the proposed LMNN is a promising step towards the ultimate goal of energy-free and light-speed AI.

Hanyu Zheng, Quan Liu, Ivan I. Kravchenko et al.

Rapid developments in machine vision have led to advances in a variety of industries, from medical image analysis to autonomous systems. These achievements, however, typically necessitate digital neural networks with heavy computational requirements, which are limited by high energy consumption and further hinder real-time decision-making when computation resources are not accessible. Here, we demonstrate an intelligent meta-imager that is designed to work in concert with a digital back-end to off-load computationally expensive convolution operations into high-speed and low-power optics. In this architecture, metasurfaces enable both angle and polarization multiplexing to create multiple information channels that perform positive and negatively valued convolution operations in a single shot. The meta-imager is employed for object classification, experimentally achieving 98.6% accurate classification of handwritten digits and 88.8% accuracy in classifying fashion images. With compactness, high speed, and low power consumption, this approach could find a wide range of applications in artificial intelligence and machine vision applications.

Xiaomei Zhang, Hanyu Zheng, Xiangyu Zhu et al.

Large Vision-Language Models (LVLMs) have shown impressive capabilities across a range of tasks that integrate visual and textual understanding, such as image captioning and visual question answering. These models are trained on large-scale image and video datasets paired with text, enabling them to bridge visual perception and natural language processing. However, their application to scientific domains, especially in interpreting complex field data commonly used in the natural sciences, remains underexplored. In this work, we introduce FieldLVLM, a novel framework designed to improve large vision-language models' understanding of field data. FieldLVLM consists of two main components: a field-aware language generation strategy and a data-compressed multimodal model tuning. The field-aware language generation strategy leverages a special-purpose machine learning pipeline to extract key physical features from field data, such as flow classification, Reynolds number, and vortex patterns. This information is then converted into structured textual descriptions that serve as a dataset. The data-compressed multimodal model tuning focuses on LVLMs with these generated datasets, using a data compression strategy to reduce the complexity of field inputs and retain only the most informative values. This ensures compatibility with the models language decoder and guides its learning more effectively. Experimental results on newly proposed benchmark datasets demonstrate that FieldLVLM significantly outperforms existing methods in tasks involving scientific field data. Our findings suggest that this approach opens up new possibilities for applying large vision-language models to scientific research, helping bridge the gap between large models and domain-specific discovery.

Binjie Guo, Hanyu Zheng, Haohan Jiang et al.

Due to the lack of a method to efficiently represent the multimodal information of a protein, including its structure and sequence information, predicting compound-protein binding affinity (CPA) still suffers from low accuracy when applying machine learning methods. To overcome this limitation, in a novel end-to-end architecture (named FeatNN), we develop a coevolutionary strategy to jointly represent the structure and sequence features of proteins and ultimately optimize the mathematical models for predicting CPA. Furthermore, from the perspective of data-driven approach, we proposed a rational method that can utilize both high- and low-quality databases to optimize the accuracy and generalization ability of FeatNN in CPA prediction tasks. Notably, we visually interpret the feature interaction process between sequence and structure in the rationally designed architecture. As a result, FeatNN considerably outperforms the state-of-the-art (SOTA) baseline in virtual drug screening tasks, indicating the feasibility of this approach for practical use. FeatNN provides an outstanding method for higher CPA prediction accuracy and better generalization ability by efficiently representing multimodal information of proteins via a coevolutionary strategy.