Xiuming Zhang

Zheng Ding, Xuaner Zhang, Zhihao Xia et al. · mit

We address the problem of learning person-specific facial priors from a small number (e.g., 20) of portrait photos of the same person. This enables us to edit this specific person's facial appearance, such as expression and lighting, while preserving their identity and high-frequency facial details. Key to our approach, which we dub DiffusionRig, is a diffusion model conditioned on, or "rigged by," crude 3D face models estimated from single in-the-wild images by an off-the-shelf estimator. On a high level, DiffusionRig learns to map simplistic renderings of 3D face models to realistic photos of a given person. Specifically, DiffusionRig is trained in two stages: It first learns generic facial priors from a large-scale face dataset and then person-specific priors from a small portrait photo collection of the person of interest. By learning the CGI-to-photo mapping with such personalized priors, DiffusionRig can "rig" the lighting, facial expression, head pose, etc. of a portrait photo, conditioned only on coarse 3D models while preserving this person's identity and other high-frequency characteristics. Qualitative and quantitative experiments show that DiffusionRig outperforms existing approaches in both identity preservation and photorealism. Please see the project website: https://diffusionrig.github.io for the supplemental material, video, code, and data.

Fengtao Zhou, Yingxue Xu, Zhengyu Zhang et al.

Comprehensive molecular profiling is essential for modern precision oncology but remains hindered by prohibitive costs, specimen exhaustion, and protracted turnaround times. While pathology foundation models (PFMs) have demonstrated potential for inferring molecular phenotypes from routine hematoxylin and eosin (H&E) whole-slide images (WSIs), current architectures primarily rely on vision-centric self-supervised learning or vision-language alignment, lacking the spatially resolved molecular supervision required to connect subtle morphological features with underlying genomic alterations. Spatial transcriptomics (ST) emerges as a transformative technology that enables transcriptomic quantification within intact tissue sections, thereby preserving the precise spatial link between histology and molecular profiles. In this study, we present a Spatial Transcriptomics-guided Alignment framework for Molecular Profiling (STAMP), which endows PFMs with intrinsic molecular awareness. To support this paradigm, we curated HumanST-1k, a human ST dataset spanning diverse anatomical organs and sequencing platforms. This atlas yields 1.8 million pairs of H&E patches and corresponding transcriptomic profiles, providing a corpus that links histological structures with their molecular states. To mitigate the technical noise inherent to raw transcriptomics, STAMP applies a pathway-informed alignment strategy that aggregates transcriptomic data into biologically functional pathways, which are subsequently integrated into PFMs via parameter-efficient fine-tuning. This alignment enriches the representation space of PFMs and unlocks their capacity to resolve sub-visual molecular signatures. The clinical utility of these augmented representations was validated through a multi-tier evaluation framework.

Ling Liang, Jiabo Ma, Zhengyu Zhang et al.

Gastric cancer remains a major cause of cancer mortality, yet its histological and molecular heterogeneity complicates diagnosis and risk stratification. General-purpose pathology foundation models (PFMs) often plateau on fine-grained endpoints central to gastric cancer care, and few have undergone rigorous prospective validation or clinical reader studies. We present GRACE, a Gastric-specific foundation model for Real-world Assessment and Clinical dEcision support. GRACE was developed from multicenter gastric pathology datasets totaling 48,364 primarily HE-stained whole-slide images from 37,493 patients. When evaluated on 28 clinically relevant tasks, GRACE consistently outperformed representative pancancer PFMs, achieving a macro-AUC of 0.9188, with strong performance for precancerous lesion diagnosis (macro-AUC 0.9322), tumor histopathological assessment (macro-AUC 0.9119), molecular profiling (macro-AUC 0.8682), and prognostic prediction. Beyond benchmarking, GRACE's translational value was substantiated through a rigorous evidence chain. Under safety-gated criteria requiring 100% NPV for rule-out and 100% PPV for rule-in, GRACE streamlined review for up to 69.6% of malignancy-diagnosis cases and triaged 46.8% of MMR-IHC follow-up requests. This translational feasibility was further strengthened by a randomized crossover reader study of pathologist-AI collaboration. With GRACE assistance, diagnostic accuracy improved from 82.0% to 89.9%, yielding nearly twofold higher adjusted odds of a correct diagnosis (OR 1.987) alongside concurrent gains in sensitivity and specificity. AI assistance also reduced diagnostic time by 14.9%, elevated diagnostic confidence by 9.0%, and markedly improved inter-rater agreement. When calibrated to maintain non-inferior performance to senior pathologists, the AI-assisted workflow could triage 60.7% of atrophy and 82.7% of intestinal metaplasia cases.

Yifan Wang, Aleksander Holynski, Xiuming Zhang et al. · mit

A light stage uses a series of calibrated cameras and lights to capture a subject's facial appearance under varying illumination and viewpoint. This captured information is crucial for facial reconstruction and relighting. Unfortunately, light stages are often inaccessible: they are expensive and require significant technical expertise for construction and operation. In this paper, we present SunStage: a lightweight alternative to a light stage that captures comparable data using only a smartphone camera and the sun. Our method only requires the user to capture a selfie video outdoors, rotating in place, and uses the varying angles between the sun and the face as guidance in joint reconstruction of facial geometry, reflectance, camera pose, and lighting parameters. Despite the in-the-wild un-calibrated setting, our approach is able to reconstruct detailed facial appearance and geometry, enabling compelling effects such as relighting, novel view synthesis, and reflectance editing. Results and interactive demos are available at https://sunstage.cs.washington.edu/.

Yingxue Xu, Yihui Wang, Fengtao Zhou et al.

Remarkable strides in computational pathology have been made in the task-agnostic foundation model that advances the performance of a wide array of downstream clinical tasks. Despite the promising performance, there are still several challenges. First, prior works have resorted to either vision-only or image-caption data, disregarding pathology reports with more clinically authentic information from pathologists and gene expression profiles which respectively offer distinct knowledge for versatile clinical applications. Second, the current progress in pathology FMs predominantly concentrates on the patch level, where the restricted context of patch-level pretraining fails to capture whole-slide patterns. Even recent slide-level FMs still struggle to provide whole-slide context for patch representation. In this study, for the first time, we develop a pathology foundation model incorporating three levels of modalities: pathology slides, pathology reports, and gene expression data, which resulted in 26,169 slide-level modality pairs from 10,275 patients across 32 cancer types, amounting to over 116 million pathological patch images. To leverage these data for CPath, we propose a novel whole-slide pretraining paradigm that injects the multimodal whole-slide context into the patch representation, called Multimodal Self-TAught PRetraining (mSTAR). The proposed paradigm revolutionizes the pretraining workflow for CPath, enabling the pathology FM to acquire the whole-slide context. To the best of our knowledge, this is the first attempt to incorporate three modalities at the whole-slide context for enhancing pathology FMs. To systematically evaluate the capabilities of mSTAR, we built the largest spectrum of oncological benchmark, spanning 7 categories of oncological applications in 15 types of 97 practical oncological tasks.

Zhengrui Guo, Zhengyu Zhang, Jiabo Ma et al.

Pathological assessment guides lung cancer diagnosis, treatment selection, and prognostic evaluation, yet current CPath approaches rely on task-specific models for isolated objectives. Although pan-cancer foundation models offer versatility, they lack subspecialty-level depth and have not been evaluated across clinical workflows or prospectively validated in real-world settings. We introduce PulmoFoundation, a multi-center, prospectively validated, randomized controlled trial (RCT)-evaluated foundation model for comprehensive lung pathology assessment across pre-operative, intra-operative, and post-operative care. Built upon Virchow2 via subspecialty-specific pretraining using ~40,000 diagnostic H&E-stained whole-slide images (WSIs), PulmoFoundation was systematically evaluated on ~26,000 WSIs across 32 clinically relevant tasks. In addition to accurately predicting molecular markers and patient survival, our model achieves clinical-grade performance in core diagnostic tasks across biopsy, frozen section, and surgical resection slides. In a registered prospective study of 1,357 patients across 11 diagnostic tasks, our model achieved an average AUC of 92.3%. Using pre-specified triage thresholds, PulmoFoundation could reduce additional second-review burden for 68.8% of biopsies and 83.0% of frozen sections, and defer 44.5% of IHC stain orders, with PPVs of 1.0, 0.991, and 0.966. Beyond prospective validation, we conducted a crossover RCT with eight pathologists, in which AI assistance improved diagnostic accuracy across 4,928 case-reader pairs (91.7% w/ AI vs. 83.8% w/o AI). AI assistance also reduced median diagnostic time by 19.6%, increased diagnostic confidence by 8.7%, and improved inter-rater agreement from moderate (kappa = 0.56) to substantial (kappa = 0.76). Together, these evaluations support PulmoFoundation as a clinically validated decision-support system for lung pathology.

Zunlei Feng, Zhonghua Wang, Xinchao Wang et al.

The microvascular invasion (MVI) is a major prognostic factor in hepatocellular carcinoma, which is one of the malignant tumors with the highest mortality rate. The diagnosis of MVI needs discovering the vessels that contain hepatocellular carcinoma cells and counting their number in each vessel, which depends heavily on experiences of the doctor, is largely subjective and time-consuming. However, there is no algorithm as yet tailored for the MVI detection from pathological images. This paper collects the first pathological liver image dataset containing 522 whole slide images with labels of vessels, MVI, and hepatocellular carcinoma grades. The first and essential step for the automatic diagnosis of MVI is the accurate segmentation of vessels. The unique characteristics of pathological liver images, such as super-large size, multi-scale vessel, and blurred vessel edges, make the accurate vessel segmentation challenging. Based on the collected dataset, we propose an Edge-competing Vessel Segmentation Network (EVS-Net), which contains a segmentation network and two edge segmentation discriminators. The segmentation network, combined with an edge-aware self-supervision mechanism, is devised to conduct vessel segmentation with limited labeled patches. Meanwhile, two discriminators are introduced to distinguish whether the segmented vessel and background contain residual features in an adversarial manner. In the training stage, two discriminators are devised tocompete for the predicted position of edges. Exhaustive experiments demonstrate that, with only limited labeled patches, EVS-Net achieves a close performance of fully supervised methods, which provides a convenient tool for the pathological liver vessel segmentation. Code is publicly available at https://github.com/zju-vipa/EVS-Net.

Yingxue Xu, Zhengyu Zhang, Xiuming Zhang et al.

Pathology foundation models have shown strong retrospective performance, but whether such systems can support clinically relevant use remains unclear. This challenge is particularly important in breast cancer, where pathological assessment serves as the gold standard for diagnosis and guides treatment planning, surgical decision-making and risk stratification across pre-, intra- and post-operative stages. Here we present \textbf{BRAVE}, a breast-adaptive pathology foundation model developed and evaluated using a total resource of 101,638 breast whole-slide images from 32 sources across Asia, Europe and North America. We assessed BRAVE across 34 tasks in 82 cohorts spanning pre-operative biopsy, intra-operative frozen section and post-operative resection, using an evidence chain comprising retrospective benchmarking, clinically challenging scenarios, workflow-oriented clinical impact simulations, prospective observational validation with the thresholds locked in the retrospective cohorts and crossover pathologist-AI interaction studies. Across these settings, BRAVE supported practical roles in the clinical workflow, including safe exclusion of low-risk cases from routine review, AI-assisted second-review rescue of initially missed positives and prioritization of cases for further assessment. In prospective validation across three centres, BRAVE excluded 76.9% of negative biopsy cases (NPV 0.953) and 70.1% of negative frozen-section cases (NPV 0.973), and triaged 78.8% of post-operative subtyping cases as high-confidence clear-cut cases (NPV 1.000). In reader studies, AI assistance improved balanced accuracy from 88.5% to 95.1% (OR 3.14, P<0.001), with better efficiency, confidence and inter-rater agreement. BRAVE-derived scores also independently predicted disease-free survival (adjusted HR 4.79, P<0.001) and overall survival (adjusted HR 8.14, P<0.001).

Yu Cai, Cheng Jin, Jiabo Ma et al.

Pathology foundation models (PFMs) have enabled robust generalization in computational pathology through large-scale datasets and expansive architectures, but their substantial computational cost, particularly for gigapixel whole slide images, limits clinical accessibility and scalability. Here, we present LitePath, a deployment-friendly foundational framework designed to mitigate model over-parameterization and patch level redundancy. LitePath integrates LiteFM, a compact model distilled from three large PFMs (Virchow2, H-Optimus-1 and UNI2) using 190 million patches, and the Adaptive Patch Selector (APS), a lightweight component for task-specific patch selection. The framework reduces model parameters by 28x and lowers FLOPs by 403.5x relative to Virchow2, enabling deployment on low-power edge hardware such as the NVIDIA Jetson Orin Nano Super. On this device, LitePath processes 208 slides per hour, 104.5x faster than Virchow2, and consumes 0.36 kWh per 3,000 slides, 171x lower than Virchow2 on an RTX3090 GPU. We validated accuracy using 37 cohorts across four organs and 26 tasks (26 internal, 9 external, and 2 prospective), comprising 15,672 slides from 9,808 patients disjoint from the pretraining data. LitePath ranks second among 19 evaluated models and outperforms larger models including H-Optimus-1, mSTAR, UNI2 and GPFM, while retaining 99.71% of the AUC of Virchow2 on average. To quantify the balance between accuracy and efficiency, we propose the Deployability Score (D-Score), defined as the weighted geometric mean of normalized AUC and normalized FLOP, where LitePath achieves the highest value, surpassing Virchow2 by 10.64%. These results demonstrate that LitePath enables rapid, cost-effective and energy-efficient pathology image analysis on accessible hardware while maintaining accuracy comparable to state-of-the-art PFMs and reducing the carbon footprint of AI deployment.

Hongyi Wang, Zhengjie Zhu, Jiabo Ma et al.

The rapid digitization of histopathology slides has opened up new possibilities for computational tools in clinical and research workflows. Among these, content-based slide retrieval stands out, enabling pathologists to identify morphologically and semantically similar cases, thereby supporting precise diagnoses, enhancing consistency across observers, and assisting example-based education. However, effective retrieval of whole slide images (WSIs) remains challenging due to their gigapixel scale and the difficulty of capturing subtle semantic differences amid abundant irrelevant content. To overcome these challenges, we present PathSearch, a retrieval framework that unifies fine-grained attentive mosaic representations with global-wise slide embeddings aligned through vision-language contrastive learning. Trained on a corpus of 6,926 slide-report pairs, PathSearch captures both fine-grained morphological cues and high-level semantic patterns to enable accurate and flexible retrieval. The framework supports two key functionalities: (1) mosaic-based image-to-image retrieval, ensuring accurate and efficient slide research; and (2) multi-modal retrieval, where text queries can directly retrieve relevant slides. PathSearch was rigorously evaluated on four public pathology datasets and three in-house cohorts, covering tasks including anatomical site retrieval, tumor subtyping, tumor vs. non-tumor discrimination, and grading across diverse organs such as breast, lung, kidney, liver, and stomach. External results show that PathSearch outperforms traditional image-to-image retrieval frameworks. A multi-center reader study further demonstrates that PathSearch improves diagnostic accuracy, boosts confidence, and enhances inter-observer agreement among pathologists in real clinical scenarios. These results establish PathSearch as a scalable and generalizable retrieval solution for digital pathology.

Huajun Zhou, Fengtao Zhou, Jiabo Ma et al.

Multimodal data provides heterogeneous information for a holistic understanding of the tumor microenvironment. However, existing AI models often struggle to harness the rich information within multimodal data and extract poorly generalizable representations. Here we present MICE (Multimodal data Integration via Collaborative Experts), a multimodal foundation model that effectively integrates pathology images, clinical reports, and genomics data for precise pan-cancer prognosis prediction. Instead of conventional multi-expert modules, MICE employs multiple functionally diverse experts to comprehensively capture both cross-cancer and cancer-specific insights. Leveraging data from 11,799 patients across 30 cancer types, we enhanced MICE's generalizability by coupling contrastive and supervised learning. MICE outperformed both unimodal and state-of-the-art multi-expert-based multimodal models, demonstrating substantial improvements in C-index ranging from 3.8% to 11.2% on internal cohorts and 5.8% to 8.8% on independent cohorts, respectively. Moreover, it exhibited remarkable data efficiency across diverse clinical scenarios. With its enhanced generalizability and data efficiency, MICE establishes an effective and scalable foundation for pan-cancer prognosis prediction, holding strong potential to personalize tailored therapies and improve treatment outcomes.

Cheng Jin, Fengtao Zhou, Yunfang Yu et al.

Precision oncology requires accurate molecular insights, yet obtaining these directly from genomics is costly and time-consuming for broad clinical use. Predicting complex molecular features and patient prognosis directly from routine whole-slide images (WSI) remains a major challenge for current deep learning methods. Here we introduce PathLUPI, which uses transcriptomic privileged information during training to extract genome-anchored histological embeddings, enabling effective molecular prediction using only WSIs at inference. Through extensive evaluation across 49 molecular oncology tasks using 11,257 cases among 20 cohorts, PathLUPI demonstrated superior performance compared to conventional methods trained solely on WSIs. Crucially, it achieves AUC $\geq$ 0.80 in 14 of the biomarker prediction and molecular subtyping tasks and C-index $\geq$ 0.70 in survival cohorts of 5 major cancer types. Moreover, PathLUPI embeddings reveal distinct cellular morphological signatures associated with specific genotypes and related biological pathways within WSIs. By effectively encoding molecular context to refine WSI representations, PathLUPI overcomes a key limitation of existing models and offers a novel strategy to bridge molecular insights with routine pathology workflows for wider clinical application.

Haoming Luo, Xiaotian Yu, Shengxuming Zhang et al.

Pathology images are considered the ``gold standard" for cancer diagnosis and treatment, with gigapixel images providing extensive tissue and cellular information. Existing methods fail to simultaneously extract global structural and local detail features for comprehensive pathology image analysis efficiently. To address these limitations, we propose a self-calibration enhanced framework for whole slide pathology image analysis, comprising three components: a global branch, a focus predictor, and a detailed branch. The global branch initially classifies using the pathological thumbnail, while the focus predictor identifies relevant regions for classification based on the last layer features of the global branch. The detailed extraction branch then assesses whether the magnified regions correspond to the lesion area. Finally, a feature consistency constraint between the global and detail branches ensures that the global branch focuses on the appropriate region and extracts sufficient discriminative features for final identification. These focused discriminative features prove invaluable for uncovering novel prognostic tumor markers from the perspective of feature cluster uniqueness and tissue spatial distribution. Extensive experiment results demonstrate that the proposed framework can rapidly deliver accurate and explainable results for pathological grading and prognosis tasks.

Shengxuming Zhang, Weihan Li, Tianhong Gao et al.

Pathological diagnosis is vital for determining disease characteristics, guiding treatment, and assessing prognosis, relying heavily on detailed, multi-scale analysis of high-resolution whole slide images (WSI). However, existing large vision-language models (LVLMs) are limited by input resolution constraints, hindering their efficiency and accuracy in pathology image analysis. To overcome these issues, we propose two innovative strategies: the mixed task-guided feature enhancement, which directs feature extraction toward lesion-related details across scales, and the prompt-guided detail feature completion, which integrates coarse- and fine-grained features from WSI based on specific prompts without compromising inference speed. Leveraging a comprehensive dataset of 490K samples from diverse pathology tasks, we trained the pathology-specialized LVLM, OmniPath. Extensive experiments demonstrate that this model significantly outperforms existing methods in diagnostic accuracy and efficiency, providing an interactive, clinically aligned approach for auxiliary diagnosis in a wide range of pathology applications.

Xiuming Zhang, Pratul P. Srinivasan, Boyang Deng et al.

We address the problem of recovering the shape and spatially-varying reflectance of an object from multi-view images (and their camera poses) of an object illuminated by one unknown lighting condition. This enables the rendering of novel views of the object under arbitrary environment lighting and editing of the object's material properties. The key to our approach, which we call Neural Radiance Factorization (NeRFactor), is to distill the volumetric geometry of a Neural Radiance Field (NeRF) [Mildenhall et al. 2020] representation of the object into a surface representation and then jointly refine the geometry while solving for the spatially-varying reflectance and environment lighting. Specifically, NeRFactor recovers 3D neural fields of surface normals, light visibility, albedo, and Bidirectional Reflectance Distribution Functions (BRDFs) without any supervision, using only a re-rendering loss, simple smoothness priors, and a data-driven BRDF prior learned from real-world BRDF measurements. By explicitly modeling light visibility, NeRFactor is able to separate shadows from albedo and synthesize realistic soft or hard shadows under arbitrary lighting conditions. NeRFactor is able to recover convincing 3D models for free-viewpoint relighting in this challenging and underconstrained capture setup for both synthetic and real scenes. Qualitative and quantitative experiments show that NeRFactor outperforms classic and deep learning-based state of the art across various tasks. Our videos, code, and data are available at people.csail.mit.edu/xiuming/projects/nerfactor/.

Steven Liu, Xiuming Zhang, Zhoutong Zhang et al.

A neural radiance field (NeRF) is a scene model supporting high-quality view synthesis, optimized per scene. In this paper, we explore enabling user editing of a category-level NeRF - also known as a conditional radiance field - trained on a shape category. Specifically, we introduce a method for propagating coarse 2D user scribbles to the 3D space, to modify the color or shape of a local region. First, we propose a conditional radiance field that incorporates new modular network components, including a shape branch that is shared across object instances. Observing multiple instances of the same category, our model learns underlying part semantics without any supervision, thereby allowing the propagation of coarse 2D user scribbles to the entire 3D region (e.g., chair seat). Next, we propose a hybrid network update strategy that targets specific network components, which balances efficiency and accuracy. During user interaction, we formulate an optimization problem that both satisfies the user's constraints and preserves the original object structure. We demonstrate our approach on various editing tasks over three shape datasets and show that it outperforms prior neural editing approaches. Finally, we edit the appearance and shape of a real photograph and show that the edit propagates to extrapolated novel views.

Pratul P. Srinivasan, Boyang Deng, Xiuming Zhang et al.

We present a method that takes as input a set of images of a scene illuminated by unconstrained known lighting, and produces as output a 3D representation that can be rendered from novel viewpoints under arbitrary lighting conditions. Our method represents the scene as a continuous volumetric function parameterized as MLPs whose inputs are a 3D location and whose outputs are the following scene properties at that input location: volume density, surface normal, material parameters, distance to the first surface intersection in any direction, and visibility of the external environment in any direction. Together, these allow us to render novel views of the object under arbitrary lighting, including indirect illumination effects. The predicted visibility and surface intersection fields are critical to our model's ability to simulate direct and indirect illumination during training, because the brute-force techniques used by prior work are intractable for lighting conditions outside of controlled setups with a single light. Our method outperforms alternative approaches for recovering relightable 3D scene representations, and performs well in complex lighting settings that have posed a significant challenge to prior work.

Yikai Li, Jiayuan Mao, Xiuming Zhang et al.

We consider two important aspects in understanding and editing images: modeling regular, program-like texture or patterns in 2D planes, and 3D posing of these planes in the scene. Unlike prior work on image-based program synthesis, which assumes the image contains a single visible 2D plane, we present Box Program Induction (BPI), which infers a program-like scene representation that simultaneously models repeated structure on multiple 2D planes, the 3D position and orientation of the planes, and camera parameters, all from a single image. Our model assumes a box prior, i.e., that the image captures either an inner view or an outer view of a box in 3D. It uses neural networks to infer visual cues such as vanishing points, wireframe lines to guide a search-based algorithm to find the program that best explains the image. Such a holistic, structured scene representation enables 3D-aware interactive image editing operations such as inpainting missing pixels, changing camera parameters, and extrapolate the image contents.

Tiancheng Sun, Zexiang Xu, Xiuming Zhang et al.

The light stage has been widely used in computer graphics for the past two decades, primarily to enable the relighting of human faces. By capturing the appearance of the human subject under different light sources, one obtains the light transport matrix of that subject, which enables image-based relighting in novel environments. However, due to the finite number of lights in the stage, the light transport matrix only represents a sparse sampling on the entire sphere. As a consequence, relighting the subject with a point light or a directional source that does not coincide exactly with one of the lights in the stage requires interpolation and resampling the images corresponding to nearby lights, and this leads to ghosting shadows, aliased specularities, and other artifacts. To ameliorate these artifacts and produce better results under arbitrary high-frequency lighting, this paper proposes a learning-based solution for the "super-resolution" of scans of human faces taken from a light stage. Given an arbitrary "query" light direction, our method aggregates the captured images corresponding to neighboring lights in the stage, and uses a neural network to synthesize a rendering of the face that appears to be illuminated by a "virtual" light source at the query location. This neural network must circumvent the inherent aliasing and regularity of the light stage data that was used for training, which we accomplish through the use of regularized traditional interpolation methods within our network. Our learned model is able to produce renderings for arbitrary light directions that exhibit realistic shadows and specular highlights, and is able to generalize across a wide variety of subjects.

Xiuming Zhang, Sean Fanello, Yun-Ta Tsai et al.

The light transport (LT) of a scene describes how it appears under different lighting and viewing directions, and complete knowledge of a scene's LT enables the synthesis of novel views under arbitrary lighting. In this paper, we focus on image-based LT acquisition, primarily for human bodies within a light stage setup. We propose a semi-parametric approach to learn a neural representation of LT that is embedded in the space of a texture atlas of known geometric properties, and model all non-diffuse and global LT as residuals added to a physically-accurate diffuse base rendering. In particular, we show how to fuse previously seen observations of illuminants and views to synthesize a new image of the same scene under a desired lighting condition from a chosen viewpoint. This strategy allows the network to learn complex material effects (such as subsurface scattering) and global illumination, while guaranteeing the physical correctness of the diffuse LT (such as hard shadows). With this learned LT, one can relight the scene photorealistically with a directional light or an HDRI map, synthesize novel views with view-dependent effects, or do both simultaneously, all in a unified framework using a set of sparse, previously seen observations. Qualitative and quantitative experiments demonstrate that our neural LT (NLT) outperforms state-of-the-art solutions for relighting and view synthesis, without separate treatment for both problems that prior work requires.

Yikai Li, Jiayuan Mao, Xiuming Zhang et al.

We study the inverse graphics problem of inferring a holistic representation for natural images. Given an input image, our goal is to induce a neuro-symbolic, program-like representation that jointly models camera poses, object locations, and global scene structures. Such high-level, holistic scene representations further facilitate low-level image manipulation tasks such as inpainting. We formulate this problem as jointly finding the camera pose and scene structure that best describe the input image. The benefits of such joint inference are two-fold: scene regularity serves as a new cue for perspective correction, and in turn, correct perspective correction leads to a simplified scene structure, similar to how the correct shape leads to the most regular texture in shape from texture. Our proposed framework, Perspective Plane Program Induction (P3I), combines search-based and gradient-based algorithms to efficiently solve the problem. P3I outperforms a set of baselines on a collection of Internet images, across tasks including camera pose estimation, global structure inference, and down-stream image manipulation tasks.

Xuaner Cecilia Zhang, Jonathan T. Barron, Yun-Ta Tsai et al.

Casually-taken portrait photographs often suffer from unflattering lighting and shadowing because of suboptimal conditions in the environment. Aesthetic qualities such as the position and softness of shadows and the lighting ratio between the bright and dark parts of the face are frequently determined by the constraints of the environment rather than by the photographer. Professionals address this issue by adding light shaping tools such as scrims, bounce cards, and flashes. In this paper, we present a computational approach that gives casual photographers some of this control, thereby allowing poorly-lit portraits to be relit post-capture in a realistic and easily-controllable way. Our approach relies on a pair of neural networks---one to remove foreign shadows cast by external objects, and another to soften facial shadows cast by the features of the subject and to add a synthetic fill light to improve the lighting ratio. To train our first network we construct a dataset of real-world portraits wherein synthetic foreign shadows are rendered onto the face, and we show that our network learns to remove those unwanted shadows. To train our second network we use a dataset of Light Stage scans of human subjects to construct input/output pairs of input images harshly lit by a small light source, and variably softened and fill-lit output images of each face. We propose a way to explicitly encode facial symmetry and show that our dataset and training procedure enable the model to generalize to images taken in the wild. Together, these networks enable the realistic and aesthetically pleasing enhancement of shadows and lights in real-world portrait images

Jiayuan Mao, Xiuming Zhang, Yikai Li et al.

Humans are capable of building holistic representations for images at various levels, from local objects, to pairwise relations, to global structures. The interpretation of structures involves reasoning over repetition and symmetry of the objects in the image. In this paper, we present the Program-Guided Image Manipulator (PG-IM), inducing neuro-symbolic program-like representations to represent and manipulate images. Given an image, PG-IM detects repeated patterns, induces symbolic programs, and manipulates the image using a neural network that is guided by the program. PG-IM learns from a single image, exploiting its internal statistics. Despite trained only on image inpainting, PG-IM is directly capable of extrapolation and regularity editing in a unified framework. Extensive experiments show that PG-IM achieves superior performance on all the tasks.

Xiuming Zhang, Zhoutong Zhang, Chengkai Zhang et al.

From a single image, humans are able to perceive the full 3D shape of an object by exploiting learned shape priors from everyday life. Contemporary single-image 3D reconstruction algorithms aim to solve this task in a similar fashion, but often end up with priors that are highly biased by training classes. Here we present an algorithm, Generalizable Reconstruction (GenRe), designed to capture more generic, class-agnostic shape priors. We achieve this with an inference network and training procedure that combine 2.5D representations of visible surfaces (depth and silhouette), spherical shape representations of both visible and non-visible surfaces, and 3D voxel-based representations, in a principled manner that exploits the causal structure of how 3D shapes give rise to 2D images. Experiments demonstrate that GenRe performs well on single-view shape reconstruction, and generalizes to diverse novel objects from categories not seen during training.

Xiuming Zhang, Tali Dekel, Tianfan Xue et al.

We present a system that allows users to visualize complex human motion via 3D motion sculptures---a representation that conveys the 3D structure swept by a human body as it moves through space. Given an input video, our system computes the motion sculptures and provides a user interface for rendering it in different styles, including the options to insert the sculpture back into the original video, render it in a synthetic scene or physically print it. To provide this end-to-end workflow, we introduce an algorithm that estimates that human's 3D geometry over time from a set of 2D images and develop a 3D-aware image-based rendering approach that embeds the sculpture back into the scene. By automating the process, our system takes motion sculpture creation out of the realm of professional artists, and makes it applicable to a wide range of existing video material. By providing viewers with 3D information, motion sculptures reveal space-time motion information that is difficult to perceive with the naked eye, and allow viewers to interpret how different parts of the object interact over time. We validate the effectiveness of this approach with user studies, finding that our motion sculpture visualizations are significantly more informative about motion than existing stroboscopic and space-time visualization methods.

Jiajun Wu, Chengkai Zhang, Xiuming Zhang et al.

The problem of single-view 3D shape completion or reconstruction is challenging, because among the many possible shapes that explain an observation, most are implausible and do not correspond to natural objects. Recent research in the field has tackled this problem by exploiting the expressiveness of deep convolutional networks. In fact, there is another level of ambiguity that is often overlooked: among plausible shapes, there are still multiple shapes that fit the 2D image equally well; i.e., the ground truth shape is non-deterministic given a single-view input. Existing fully supervised approaches fail to address this issue, and often produce blurry mean shapes with smooth surfaces but no fine details. In this paper, we propose ShapeHD, pushing the limit of single-view shape completion and reconstruction by integrating deep generative models with adversarially learned shape priors. The learned priors serve as a regularizer, penalizing the model only if its output is unrealistic, not if it deviates from the ground truth. Our design thus overcomes both levels of ambiguity aforementioned. Experiments demonstrate that ShapeHD outperforms state of the art by a large margin in both shape completion and shape reconstruction on multiple real datasets.

Xingyuan Sun, Jiajun Wu, Xiuming Zhang et al.

We study 3D shape modeling from a single image and make contributions to it in three aspects. First, we present Pix3D, a large-scale benchmark of diverse image-shape pairs with pixel-level 2D-3D alignment. Pix3D has wide applications in shape-related tasks including reconstruction, retrieval, viewpoint estimation, etc. Building such a large-scale dataset, however, is highly challenging; existing datasets either contain only synthetic data, or lack precise alignment between 2D images and 3D shapes, or only have a small number of images. Second, we calibrate the evaluation criteria for 3D shape reconstruction through behavioral studies, and use them to objectively and systematically benchmark cutting-edge reconstruction algorithms on Pix3D. Third, we design a novel model that simultaneously performs 3D reconstruction and pose estimation; our multi-task learning approach achieves state-of-the-art performance on both tasks.