Zhuo Deng

Weihao Gao, Zhuo Deng, Zhiyuan Niu et al.

Large multimodal language models (LMMs) have achieved significant success in general domains. However, due to the significant differences between medical images and text and general web content, the performance of LMMs in medical scenarios is limited. In ophthalmology, clinical diagnosis relies on multiple modalities of medical images, but unfortunately, multimodal ophthalmic large language models have not been explored to date. In this paper, we study and construct an ophthalmic large multimodal model. Firstly, we use fundus images as an entry point to build a disease assessment and diagnosis pipeline to achieve common ophthalmic disease diagnosis and lesion segmentation. Then, we establish a new ophthalmic multimodal instruction-following and dialogue fine-tuning dataset based on disease-related knowledge data and publicly available real-world medical dialogue. We introduce visual ability into the large language model to complete the ophthalmic large language and vision assistant (OphGLM). Our experimental results demonstrate that the OphGLM model performs exceptionally well, and it has the potential to revolutionize clinical applications in ophthalmology. The dataset, code, and models will be made publicly available at https://github.com/ML-AILab/OphGLM.

Zhicheng Du, Changyue Liu, Wenji Xi et al.

Reported retrieval scores for training-free shape descriptors conflate local signal design, normalization, aggregation, codebook fitting, and metric choices, making isolated component evaluation difficult. This paper reframes descriptor evaluation as a {\em protocol audit}. We introduce Diffused Geodesic Moments (DGM), a seed-conditioned descriptor that computes sparse implicit heat responses, converts them to distance-like fields, and summarizes each vertex by low-order moments across seeds and scales. DGM is used both as a practical non-spectral baseline and as an instrument for isolating protocol effects. On the registered FAUST benchmark split (FAUST-Reg) and the TOSCA shape collection, aggregation-matched experiments show that an independent Geometric Moment Shape Descriptor baseline built on Heat Kernel Signature features (GMSD-HKS) obtains the highest scores in this implementation ($0.621/0.820$ and $0.865/0.963$ mean average precision (mAP)/top-1), Wave Kernel Signature (WKS) remains a strong classical signal, and DGM is useful mainly when sparse solves, non-spectral deployment, or symmetry-informative seed frames are priorities. The broader finding is methodological: the input field and aggregation protocol can dominate the moment formula. The paper contributes a reproducible protocol-cascade analysis, a cross-shape alignment diagnostic for functional-map compatibility, and concrete recommendations for designing and reporting training-free shape descriptors.

Weihao Gao, Zheng Gong, Zhuo Deng et al.

Tabular data is the most common type of data in real-life scenarios. In this study, we propose the TabKANet model for tabular data modeling, which targets the bottlenecks in learning from numerical content. We constructed a Kolmogorov-Arnold Network (KAN) based Numerical Embedding Module and unified numerical and categorical features encoding within a Transformer architecture. TabKANet has demonstrated stable and significantly superior performance compared to Neural Networks (NNs) across multiple public datasets in binary classification, multi-class classification, and regression tasks. Its performance is comparable to or surpasses that of Gradient Boosted Decision Tree models (GBDTs). Our code is publicly available on GitHub: https://github.com/AI-thpremed/TabKANet.

Zhicheng Du, Wenji Xi, Zhuo Deng et al.

Let $G_n$ be the coprime graph on $\{1,\ldots,n\}$. We prove that the mixed vertex-coloring coprime Ramsey number satisfies \[ \Rcop(k_1,\ldots,k_c)=p_{\sum_{i=1}^c(k_i-1)}, \] where $p_m$ is the $m$-th prime. The proof is elementary: the prime clique $\{1\}\cup\{p\le n:p\text{ prime}\}$ gives the upper bound by pigeonhole, while a prime-bin partition gives the matching lower bound by coloring each composite with a bin containing one of its prime divisors. We reserve $\Rcop$ for this vertex-coloring parameter; the edge-coloring parameter on the same host graph is denoted $\Redge$. The same certificate viewpoint yields three extensions: a support-disjointness generalization, a polynomial-time certificate-extraction primitive, and an exact reduction of the edge-coloring variant to classical Ramsey numbers: $\Redge(k_1,\ldots,k_c)=p_{\Rcl(k_1,\ldots,k_c)-1}$. These two formulas are rank transfers from the same clique-label certificate. We also prove that the balanced two-color diagonal threshold equals the unrestricted threshold $p_{2k-2}$ for all $k\ge2$, via a deterministic prime-bin split requiring only the weak inequality $2p_m<p_{2m}<3p_m$; for fixed $c$, a Hall argument plus a standard Selberg--Delange estimate gives eventual multicolor balanced certificates.

Jing Liang, Zhuo Deng, Zheming Zhou et al.

We extend our previous work, PoCo, and present a new algorithm, Cross-Source-Context Place Recognition (CSCPR), for RGB-D indoor place recognition that integrates global retrieval and reranking into an end-to-end model and keeps the consistency of using Context-of-Clusters (CoCs) for feature processing. Unlike prior approaches that primarily focus on the RGB domain for place recognition reranking, CSCPR is designed to handle the RGB-D data. We apply the CoCs to handle cross-sourced and cross-scaled RGB-D point clouds and introduce two novel modules for reranking: the Self-Context Cluster (SCC) and the Cross Source Context Cluster (CSCC), which enhance feature representation and match query-database pairs based on local features, respectively. We also release two new datasets, ScanNetIPR and ARKitIPR. Our experiments demonstrate that CSCPR significantly outperforms state-of-the-art models on these datasets by at least 29.27% in Recall@1 on the ScanNet-PR dataset and 43.24% in the new datasets. Code and datasets will be released.

Xiaotong Chen, Zheming Zhou, Zhuo Deng et al.

Reconstructing transparent objects using affordable RGB-D cameras is a persistent challenge in robotic perception due to inconsistent appearances across views in the RGB domain and inaccurate depth readings in each single-view. We introduce a two-stage pipeline for reconstructing transparent objects tailored for mobile platforms. In the first stage, off-the-shelf monocular object segmentation and depth completion networks are leveraged to predict the depth of transparent objects, furnishing single-view shape prior. Subsequently, we propose Epipolar-guided Optical Flow (EOF) to fuse several single-view shape priors from the first stage to a cross-view consistent 3D reconstruction given camera poses estimated from opaque part of the scene. Our key innovation lies in EOF which employs boundary-sensitive sampling and epipolar-line constraints into optical flow to accurately establish 2D correspondences across multiple views on transparent objects. Quantitative evaluations demonstrate that our pipeline significantly outperforms baseline methods in 3D reconstruction quality, paving the way for more adept robotic perception and interaction with transparent objects.

Weihao Gao, Zhuo Deng, Zheng Gong et al.

Early detection of colorectal cancer hinges on real-time, accurate polyp identification and resection. Yet current high-precision segmentation models rely on GPUs, making them impractical to deploy in primary hospitals, mobile endoscopy units, or capsule robots. To bridge this gap, we present the UltraSeg family, operating in an extreme-compression regime (<0.3 M parameters). UltraSeg-108K (0.108 M parameters) is optimized for single-center data, while UltraSeg-130K (0.13 M parameters) generalizes to multi-center, multi-modal images. By jointly optimizing encoder-decoder widths, incorporating constrained dilated convolutions to enlarge receptive fields, and integrating a cross-layer lightweight fusion module, the models achieve 90 FPS on a single CPU core without sacrificing accuracy. Evaluated on seven public datasets, UltraSeg retains >94% of the Dice score of a 31 M-parameter U-Net while utilizing only 0.4% of its parameters, establishing a strong, clinically viable baseline for the extreme-compression domain and offering an immediately deployable solution for resource-constrained settings. This work provides not only a CPU-native solution for colonoscopy but also a reproducible blueprint for broader minimally invasive surgical vision applications. Source code is publicly available to ensure reproducibility and facilitate future benchmarking.

Zhuo Deng, Yuanhao Cai, Lu Chen et al.

Ophthalmologists have used fundus images to screen and diagnose eye diseases. However, different equipments and ophthalmologists pose large variations to the quality of fundus images. Low-quality (LQ) degraded fundus images easily lead to uncertainty in clinical screening and generally increase the risk of misdiagnosis. Thus, real fundus image restoration is worth studying. Unfortunately, real clinical benchmark has not been explored for this task so far. In this paper, we investigate the real clinical fundus image restoration problem. Firstly, We establish a clinical dataset, Real Fundus (RF), including 120 low- and high-quality (HQ) image pairs. Then we propose a novel Transformer-based Generative Adversarial Network (RFormer) to restore the real degradation of clinical fundus images. The key component in our network is the Window-based Self-Attention Block (WSAB) which captures non-local self-similarity and long-range dependencies. To produce more visually pleasant results, a Transformer-based discriminator is introduced. Extensive experiments on our clinical benchmark show that the proposed RFormer significantly outperforms the state-of-the-art (SOTA) methods. In addition, experiments of downstream tasks such as vessel segmentation and optic disc/cup detection demonstrate that our proposed RFormer benefits clinical fundus image analysis and applications. The dataset, code, and models are publicly available at https://github.com/dengzhuo-AI/Real-Fundus

Weihao Gao, Zhuo Deng, Zheng Gong et al.

Insulin resistance (IR) is a key precursor to diabetes and a significant risk factor for cardiovascular disease. Traditional IR assessment methods require multiple blood tests. We developed a simple AI model using only fasting blood glucose to predict IR in non-diabetic populations. Data from the NHANES (1999-2020) and CHARLS (2015) studies were used for model training and validation. Input features included age, gender, height, weight, blood pressure, waist circumference, and fasting blood glucose. The CatBoost algorithm achieved AUC values of 0.8596 (HOMA-IR) and 0.7777 (TyG index) in NHANES, with an external AUC of 0.7442 for TyG. For METS-IR prediction, the model achieved AUC values of 0.9731 (internal) and 0.9591 (external), with RMSE values of 3.2643 (internal) and 3.057 (external). SHAP analysis highlighted waist circumference as a key predictor of IR. This AI model offers a minimally invasive and effective tool for IR prediction, supporting early diabetes and cardiovascular disease prevention.

Zheng Gong, Zhuo Deng, Run Gan et al.

The retinal fundus images are utilized extensively in the diagnosis, and their quality can directly affect the diagnosis results. However, due to the insufficient dataset and algorithm application, current fundus image quality assessment (FIQA) methods are not powerful enough to meet ophthalmologists` demands. In this paper, we address the limitations of datasets and algorithms in FIQA. First, we establish a new FIQA dataset, Fundus Quality Score(FQS), which includes 2246 fundus images with two labels: a continuous Mean Opinion Score varying from 0 to 100 and a three-level quality label. Then, we propose a FIQA Transformer-based Hypernetwork (FTHNet) to solve these tasks with regression results rather than classification results in conventional FIQA works. The FTHNet is optimized for the FIQA tasks with extensive experiments. Results on our FQS dataset show that the FTHNet can give quality scores for fundus images with PLCC of 0.9423 and SRCC of 0.9488, significantly outperforming other methods with fewer parameters and less computation complexity.We successfully build a dataset and model addressing the problems of current FIQA methods. Furthermore, the model deployment experiments demonstrate its potential in automatic medical image quality control. All experiments are carried out with 10-fold cross-validation to ensure the significance of the results.

Jing Liang, Zhuo Deng, Zheming Zhou et al.

We present a novel end-to-end algorithm (PoCo) for the indoor RGB-D place recognition task, aimed at identifying the most likely match for a given query frame within a reference database. The task presents inherent challenges attributed to the constrained field of view and limited range of perception sensors. We propose a new network architecture, which generalizes the recent Context of Clusters (CoCs) to extract global descriptors directly from the noisy point clouds through end-to-end learning. Moreover, we develop the architecture by integrating both color and geometric modalities into the point features to enhance the global descriptor representation. We conducted evaluations on public datasets ScanNet-PR and ARKit with 807 and 5047 scenarios, respectively. PoCo achieves SOTA performance: on ScanNet-PR, we achieve R@1 of 64.63%, a 5.7% improvement from the best-published result CGis (61.12%); on Arkit, we achieve R@1 of 45.12%, a 13.3% improvement from the best-published result CGis (39.82%). In addition, PoCo shows higher efficiency than CGis in inference time (1.75X-faster), and we demonstrate the effectiveness of PoCo in recognizing places within a real-world laboratory environment.

Zheng Gong, Zhuo Deng, Weihao Gao et al.

Cataract is one of the most common blinding eye diseases and can be treated by surgery. However, because cataract patients may also suffer from other blinding eye diseases, ophthalmologists must diagnose them before surgery. The cloudy lens of cataract patients forms a hazy degeneration in the fundus images, making it challenging to observe the patient's fundus vessels, which brings difficulties to the diagnosis process. To address this issue, this paper establishes a new cataract image restoration method named Catintell. It contains a cataract image synthesizing model, Catintell-Syn, and a restoration model, Catintell-Res. Catintell-Syn uses GAN architecture with fully unsupervised data to generate paired cataract-like images with realistic style and texture rather than the conventional Gaussian degradation algorithm. Meanwhile, Catintell-Res is an image restoration network that can improve the quality of real cataract fundus images using the knowledge learned from synthetic cataract images. Extensive experiments show that Catintell-Res outperforms other cataract image restoration methods in PSNR with 39.03 and SSIM with 0.9476. Furthermore, the universal restoration ability that Catintell-Res gained from unpaired cataract images can process cataract images from various datasets. We hope the models can help ophthalmologists identify other blinding eye diseases of cataract patients and inspire more medical image restoration methods in the future.

Chenyan Wu, Yukun Chen, Jiajia Luo et al.

Body orientation estimation provides crucial visual cues in many applications, including robotics and autonomous driving. It is particularly desirable when 3-D pose estimation is difficult to infer due to poor image resolution, occlusion or indistinguishable body parts. We present COCO-MEBOW (Monocular Estimation of Body Orientation in the Wild), a new large-scale dataset for orientation estimation from a single in-the-wild image. The body-orientation labels for around 130K human bodies within 55K images from the COCO dataset have been collected using an efficient and high-precision annotation pipeline. We also validated the benefits of the dataset. First, we show that our dataset can substantially improve the performance and the robustness of a human body orientation estimation model, the development of which was previously limited by the scale and diversity of the available training data. Additionally, we present a novel triple-source solution for 3-D human pose estimation, where 3-D pose labels, 2-D pose labels, and our body-orientation labels are all used in joint training. Our model significantly outperforms state-of-the-art dual-source solutions for monocular 3-D human pose estimation, where training only uses 3-D pose labels and 2-D pose labels. This substantiates an important advantage of MEBOW for 3-D human pose estimation, which is particularly appealing because the per-instance labeling cost for body orientations is far less than that for 3-D poses. The work demonstrates high potential of MEBOW in addressing real-world challenges involving understanding human behaviors. Further information of this work is available at https://chenyanwu.github.io/MEBOW/.