Melika Emami

Golara Ahmadi Azar, Qin Hu, Melika Emami et al.

Hand gesture recognition (HGR) has gained significant attention due to the increasing use of AI-powered human-computer interfaces that can interpret the deep spatiotemporal dynamics of biosignals from the peripheral nervous system, such as surface electromyography (sEMG). These interfaces have a range of applications, including the control of extended reality, agile prosthetics, and exoskeletons. However, the natural variability of sEMG among individuals has led researchers to focus on subject-specific solutions. Deep learning methods, which often have complex structures, are particularly data-hungry and can be time-consuming to train, making them less practical for subject-specific applications. In this paper, we propose and develop a generalizable, sequential decoder of transient high-density sEMG (HD-sEMG) that achieves 73% average accuracy on 65 gestures for partially-observed subjects through subject-embedded transfer learning, leveraging pre-knowledge of HGR acquired during pre-training. The use of transient HD-sEMG before gesture stabilization allows us to predict gestures with the ultimate goal of counterbalancing system control delays. The results show that the proposed generalized models significantly outperform subject-specific approaches, especially when the training data is limited, and there is a significant number of gesture classes. By building on pre-knowledge and incorporating a multiplicative subject-embedded structure, our method comparatively achieves more than 13% average accuracy across partially observed subjects with minimal data availability. This work highlights the potential of HD-sEMG and demonstrates the benefits of modeling common patterns across users to reduce the need for large amounts of data for new users, enhancing practicality.

Masoud Monajatipoor, Jiaxin Yang, Joel Stremmel et al.

Large Language Models (LLMs) demonstrate remarkable versatility in various NLP tasks but encounter distinct challenges in biomedical due to the complexities of language and data scarcity. This paper investigates LLMs application in the biomedical domain by exploring strategies to enhance their performance for the NER task. Our study reveals the importance of meticulously designed prompts in the biomedical. Strategic selection of in-context examples yields a marked improvement, offering ~15-20\% increase in F1 score across all benchmark datasets for biomedical few-shot NER. Additionally, our results indicate that integrating external biomedical knowledge via prompting strategies can enhance the proficiency of general-purpose LLMs to meet the specialized needs of biomedical NER. Leveraging a medical knowledge base, our proposed method, DiRAG, inspired by Retrieval-Augmented Generation (RAG), can boost the zero-shot F1 score of LLMs for biomedical NER. Code is released at \url{https://github.com/masoud-monajati/LLM_Bio_NER}

Ekaterina Redekop, Zichen Wang, Rushikesh Kulkarni et al.

Longitudinal data in electronic health records (EHRs) represent an individual`s clinical history through a sequence of codified concepts, including diagnoses, procedures, medications, and laboratory tests. Generative pre-trained transformers (GPT) can leverage this data to predict future events. While fine-tuning of these models can enhance task-specific performance, it becomes costly when applied to many clinical prediction tasks. In contrast, a pretrained foundation model can be used in zero-shot forecasting setting, offering a scalable alternative to fine-tuning separate models for each outcome. This study presents the first comprehensive analysis of zero-shot forecasting with GPT-based foundational models in EHRs, introducing a novel pipeline that formulates medical concept prediction as a generative modeling task. Unlike supervised approaches requiring extensive labeled data, our method enables the model to forecast a next medical event purely from a pretraining knowledge. We evaluate performance across multiple time horizons and clinical categories, demonstrating model`s ability to capture latent temporal dependencies and complex patient trajectories without task supervision. Model performance for predicting the next medical concept was evaluated using precision and recall metrics, achieving an average top1 precision of 0.614 and recall of 0.524. For 12 major diagnostic conditions, the model demonstrated strong zero-shot performance, achieving high true positive rates while maintaining low false positives. We demonstrate the power of a foundational EHR GPT model in capturing diverse phenotypes and enabling robust, zero-shot forecasting of clinical outcomes. This capability enhances the versatility of predictive healthcare models and reduces the need for task-specific training, enabling more scalable applications in clinical settings.

Golara Ahmadi Azar, Melika Emami, Alyson Fletcher et al.

Embeddings are a basic initial feature extraction step in many machine learning models, particularly in natural language processing. An embedding attempts to map data tokens to a low-dimensional space where similar tokens are mapped to vectors that are close to one another by some metric in the embedding space. A basic question is how well can such embedding be learned? To study this problem, we consider a simple probability model for discrete data where there is some "true" but unknown embedding where the correlation of random variables is related to the similarity of the embeddings. Under this model, it is shown that the embeddings can be learned by a variant of low-rank approximate message passing (AMP) method. The AMP approach enables precise predictions of the accuracy of the estimation in certain high-dimensional limits. In particular, the methodology provides insight on the relations of key parameters such as the number of samples per value, the frequency of the terms, and the strength of the embedding correlation on the probability distribution. Our theoretical findings are validated by simulations on both synthetic data and real text data.