Farzana Rahman

Megha Hegde, Jean-Christophe Nebel, Farzana Rahman

Interpreting the effects of variants within the human genome and proteome is essential for analysing disease risk, predicting medication response, and developing personalised health interventions. Due to the intrinsic similarities between the structure of natural languages and genetic sequences, natural language processing techniques have demonstrated great applicability in computational variant effect prediction. In particular, the advent of the Transformer has led to significant advancements in the field. However, Transformer-based models are not without their limitations, and a number of extensions and alternatives have been developed to improve results and enhance computational efficiency. This review explores the use of language models for computational variant effect prediction over the past decade, analysing the main architectures, and identifying key trends and future directions.

Mohammad Billah, Farzana Rahman, Arash Maskooki et al.

Connected vehicle and driver's assistance applications are greatly facilitated by Enhanced Digital Maps (EDMs) that represent roadway features (e.g., lane edges or centerlines, stop bars). Due to the large number of signalized intersections and miles of roadway, manual development of EDMs on a global basis is not feasible. Mobile Terrestrial Laser Scanning (MTLS) is the preferred data acquisition method to provide data for automated EDM development. Such systems provide an MTLS trajectory and a point cloud for the roadway environment. The challenge is to automatically convert these data into an EDM. This article presents a new processing and feature extraction method, experimental demonstration providing SAE-J2735 map messages for eleven example intersections, and a discussion of the results that points out remaining challenges and suggests directions for future research.