Hongyu Hu

Tiancheng Lin, Zhimiao Yu, Hongyu Hu et al.

Multi-instance learning (MIL) is an effective paradigm for whole-slide pathological images (WSIs) classification to handle the gigapixel resolution and slide-level label. Prevailing MIL methods primarily focus on improving the feature extractor and aggregator. However, one deficiency of these methods is that the bag contextual prior may trick the model into capturing spurious correlations between bags and labels. This deficiency is a confounder that limits the performance of existing MIL methods. In this paper, we propose a novel scheme, Interventional Bag Multi-Instance Learning (IBMIL), to achieve deconfounded bag-level prediction. Unlike traditional likelihood-based strategies, the proposed scheme is based on the backdoor adjustment to achieve the interventional training, thus is capable of suppressing the bias caused by the bag contextual prior. Note that the principle of IBMIL is orthogonal to existing bag MIL methods. Therefore, IBMIL is able to bring consistent performance boosting to existing schemes, achieving new state-of-the-art performance. Code is available at https://github.com/HHHedo/IBMIL.

Hongyu Hu, Jiyuan Zhang, Minyi Zhao et al.

Nowadays, the research on Large Vision-Language Models (LVLMs) has been significantly promoted thanks to the success of Large Language Models (LLM). Nevertheless, these Vision-Language Models (VLMs) are suffering from the drawback of hallucination -- due to insufficient understanding of vision and language modalities, VLMs may generate incorrect perception information when doing downstream applications, for example, captioning a non-existent entity. To address the hallucination phenomenon, on the one hand, we introduce a Contrastive Instruction Evaluation Method (CIEM), which is an automatic pipeline that leverages an annotated image-text dataset coupled with an LLM to generate factual/contrastive question-answer pairs for the evaluation of the hallucination of VLMs. On the other hand, based on CIEM, we further propose a new instruction tuning method called CIT (the abbreviation of Contrastive Instruction Tuning) to alleviate the hallucination of VLMs by automatically producing high-quality factual/contrastive question-answer pairs and corresponding justifications for model tuning. Through extensive experiments on CIEM and CIT, we pinpoint the hallucination issues commonly present in existing VLMs, the disability of the current instruction-tuning dataset to handle the hallucination phenomenon and the superiority of CIT-tuned VLMs over both CIEM and public datasets.

Yunwen Huang, Hongyu Hu, Ying Zhu et al.

Deep learning based Computer Aided Diagnosis (CAD) systems have been developed to treat breast ultrasound. Most of them focus on a single ultrasound imaging modality, either using representative static images or the dynamic video of a real-time scan. In fact, these two image modalities are complementary for lesion diagnosis. Dynamic videos provide detailed three-dimensional information about the lesion, while static images capture the typical sections of the lesion. In this work, we propose a multi-modality breast tumor diagnosis model to imitate the diagnosing process of radiologists, which learns the features of both static images and dynamic video and explores the potential relationship between the two modalities. Considering that static images are carefully selected by professional radiologists, we propose to aggregate dynamic video features under the guidance of domain knowledge from static images before fusing multi-modality features. Our work is validated on a breast ultrasound dataset composed of 897 sets of ultrasound images and videos. Experimental results show that our model boosts the performance of Benign/Malignant classification, achieving 90.0% in AUC and 81.7% in accuracy.

Hongyu Hu, Tiancheng Lin, Jie Wang et al.

Large-scale vision-language models (VLMs), e.g., CLIP, learn broad visual concepts from tedious training data, showing superb generalization ability. Amount of prompt learning methods have been proposed to efficiently adapt the VLMs to downstream tasks with only a few training samples. We introduce a novel method to improve the prompt learning of vision-language models by incorporating pre-trained large language models (LLMs), called Dual-Aligned Prompt Tuning (DuAl-PT). Learnable prompts, like CoOp, implicitly model the context through end-to-end training, which are difficult to control and interpret. While explicit context descriptions generated by LLMs, like GPT-3, can be directly used for zero-shot classification, such prompts are overly relying on LLMs and still underexplored in few-shot domains. With DuAl-PT, we propose to learn more context-aware prompts, benefiting from both explicit and implicit context modeling. To achieve this, we introduce a pre-trained LLM to generate context descriptions, and we encourage the prompts to learn from the LLM's knowledge by alignment, as well as the alignment between prompts and local image features. Empirically, DuAl-PT achieves superior performance on 11 downstream datasets on few-shot recognition and base-to-new generalization. Hopefully, DuAl-PT can serve as a strong baseline. Code will be available.