Shuhui Cai

Xiwei Deng, Xianchun He, Jianfeng Bao et al.

CT report generation (CTRG) aims to automatically generate diagnostic reports for 3D volumes, relieving clinicians' workload and improving patient care. Despite clinical value, existing works fail to effectively incorporate diagnostic information from multiple anatomical views and lack related clinical expertise essential for accurate and reliable diagnosis. To resolve these limitations, we propose a novel Multi-view perception Knowledge-enhanced TansfoRmer (MvKeTR) to mimic the diagnostic workflow of clinicians. Just as radiologists first examine CT scans from multiple planes, a Multi-View Perception Aggregator (MVPA) with view-aware attention is proposed to synthesize diagnostic information from multiple anatomical views effectively. Then, inspired by how radiologists further refer to relevant clinical records to guide diagnostic decision-making, a Cross-Modal Knowledge Enhancer (CMKE) is devised to retrieve the most similar reports based on the query volume to incorporate domain knowledge into the diagnosis procedure. Furthermore, instead of traditional MLPs, we employ Kolmogorov-Arnold Networks (KANs) as the fundamental building blocks of both modules, which exhibit superior parameter efficiency and reduced spectral bias to better capture high-frequency components critical for CT interpretation while mitigating overfitting. Extensive experiments on the public CTRG-Chest-548 K dataset demonstrate that our method outpaces prior state-of-the-art (SOTA) models across almost all metrics. The code is available at https://github.com/xiweideng/MvKeTR.

Linyu Fan, Che Wang, Ming Ye et al.

Data-centric artificial intelligence (AI) has remarkably advanced medical imaging, with emerging methods using synthetic data to address data scarcity while introducing synthetic-to-real gaps. Unsupervised domain adaptation (UDA) shows promise in ground truth-scarce tasks, but its application in reconstruction remains underexplored. Although multiple overlapping-echo detachment (MOLED) achieves ultra-fast multi-parametric reconstruction, extending its application to various clinical scenarios, the quality suffers from deficiency in mitigating the domain gap, difficulty in maintaining structural integrity, and inadequacy in ensuring mapping accuracy. To resolve these issues, we proposed frequency-aware perturbation and selection (FPS), comprising Wasserstein distance-modulated frequency-aware perturbation (WDFP) and hierarchical frequency-aware selection network (HFSNet), which integrates frequency-aware adaptive selection (FAS), compact FAS (cFAS) and feature-aware architecture integration (FAI). Specifically, perturbation activates domain-invariant feature learning within uncertainty, while selection refines optimal solutions within perturbation, establishing a robust and closed-loop learning pathway. Extensive experiments on synthetic data, along with diverse real clinical cases from 5 healthy volunteers, 94 ischemic stroke patients, and 46 meningioma patients, demonstrate the superiority and clinical applicability of FPS. Furthermore, FPS is applied to diffusion tensor imaging (DTI), underscoring its versatility and potential for broader medical applications. The code is available at https://github.com/flyannie/FPS.

Congbo Cai, Yiqing Zeng, Chao Wang et al.

Purpose: An end-to-end deep convolutional neural network (CNN) based on deep residual network (ResNet) was proposed to efficiently reconstruct reliable T2 mapping from single-shot OverLapping-Echo Detachment (OLED) planar imaging. Methods: The training dataset was obtained from simulations carried out on SPROM software developed by our group. The relationship between the original OLED image containing two echo signals and the corresponded T2 mapping was learned by ResNet training. After the ResNet was trained, it was applied to reconstruct the T2 mapping from simulation and in vivo human brain data. Results: Though the ResNet was trained entirely on simulated data, the trained network was generalized well to real human brain data. The results from simulation and in vivo human brain experiments show that the proposed method significantly outperformed the echo-detachment-based method. Reliable T2 mapping was achieved within tens of milliseconds after the network had been trained while the echo-detachment-based OLED reconstruction method took minutes. Conclusion: The proposed method will greatly facilitate real-time dynamic and quantitative MR imaging via OLED sequence, and ResNet has the potential to reconstruct images from complex MRI sequence efficiently.