Andrew J. Bulpitt

Mohammed M. Alghamdi, He Wang, Andrew J. Bulpitt et al.

We propose a novel method for generating high-resolution videos of talking-heads from speech audio and a single 'identity' image. Our method is based on a convolutional neural network model that incorporates a pre-trained StyleGAN generator. We model each frame as a point in the latent space of StyleGAN so that a video corresponds to a trajectory through the latent space. Training the network is in two stages. The first stage is to model trajectories in the latent space conditioned on speech utterances. To do this, we use an existing encoder to invert the generator, mapping from each video frame into the latent space. We train a recurrent neural network to map from speech utterances to displacements in the latent space of the image generator. These displacements are relative to the back-projection into the latent space of an identity image chosen from the individuals depicted in the training dataset. In the second stage, we improve the visual quality of the generated videos by tuning the image generator on a single image or a short video of any chosen identity. We evaluate our model on standard measures (PSNR, SSIM, FID and LMD) and show that it significantly outperforms recent state-of-the-art methods on one of two commonly used datasets and gives comparable performance on the other. Finally, we report on ablation experiments that validate the components of the model. The code and videos from experiments can be found at https://mohammedalghamdi.github.io/talking-heads-acm-mm

Rebecca S Stone, Nishant Ravikumar, Andrew J Bulpitt et al.

Deep neural networks are highly susceptible to learning biases in visual data. While various methods have been proposed to mitigate such bias, the majority require explicit knowledge of the biases present in the training data in order to mitigate. We argue the relevance of exploring methods which are completely ignorant of the presence of any bias, but are capable of identifying and mitigating them. Furthermore, we propose using Bayesian neural networks with a predictive uncertainty-weighted loss function to dynamically identify potential bias in individual training samples and to weight them during training. We find a positive correlation between samples subject to bias and higher epistemic uncertainties. Finally, we show the method has potential to mitigate visual bias on a bias benchmark dataset and on a real-world face detection problem, and we consider the merits and weaknesses of our approach.

Pedro Esteban Chavarrias Solano, Andrew Bulpitt, Venkataraman Subramanian et al.

Colonoscopy screening is the gold standard procedure for assessing abnormalities in the colon and rectum, such as ulcers and cancerous polyps. Measuring the abnormal mucosal area and its 3D reconstruction can help quantify the surveyed area and objectively evaluate disease burden. However, due to the complex topology of these organs and variable physical conditions, for example, lighting, large homogeneous texture, and image modality estimating distance from the camera aka depth) is highly challenging. Moreover, most colonoscopic video acquisition is monocular, making the depth estimation a non-trivial problem. While methods in computer vision for depth estimation have been proposed and advanced on natural scene datasets, the efficacy of these techniques has not been widely quantified on colonoscopy datasets. As the colonic mucosa has several low-texture regions that are not well pronounced, learning representations from an auxiliary task can improve salient feature extraction, allowing estimation of accurate camera depths. In this work, we propose to develop a novel multi-task learning (MTL) approach with a shared encoder and two decoders, namely a surface normal decoder and a depth estimator decoder. Our depth estimator incorporates attention mechanisms to enhance global context awareness. We leverage the surface normal prediction to improve geometric feature extraction. Also, we apply a cross-task consistency loss among the two geometrically related tasks, surface normal and camera depth. We demonstrate an improvement of 14.17% on relative error and 10.4% improvement on $δ_{1}$ accuracy over the most accurate baseline state-of-the-art BTS approach. All experiments are conducted on a recently released C3VD dataset; thus, we provide a first benchmark of state-of-the-art methods.

Rebecca S. Stone, Pedro E. Chavarrias-Solano, Andrew J. Bulpitt et al.

While several previous studies have devised methods for segmentation of polyps, most of these methods are not rigorously assessed on multi-center datasets. Variability due to appearance of polyps from one center to another, difference in endoscopic instrument grades, and acquisition quality result in methods with good performance on in-distribution test data, and poor performance on out-of-distribution or underrepresented samples. Unfair models have serious implications and pose a critical challenge to clinical applications. We adapt an implicit bias mitigation method which leverages Bayesian predictive uncertainties during training to encourage the model to focus on underrepresented sample regions. We demonstrate the potential of this approach to improve generalisability without sacrificing state-of-the-art performance on a challenging multi-center polyp segmentation dataset (PolypGen) with different centers and image modalities.

Rebecca S Stone, Nishant Ravikumar, Andrew J Bulpitt et al.

The fairness of a deep neural network is strongly affected by dataset bias and spurious correlations, both of which are usually present in modern feature-rich and complex visual datasets. Due to the difficulty and variability of the task, no single de-biasing method has been universally successful. In particular, implicit methods not requiring explicit knowledge of bias variables are especially relevant for real-world applications. We propose a novel implicit mitigation method using a Bayesian neural network, allowing us to leverage the relationship between epistemic uncertainties and the presence of bias or spurious correlations in a sample. Our proposed posterior estimate sharpening procedure encourages the network to focus on core features that do not contribute to high uncertainties. Experimental results on three benchmark datasets demonstrate that Bayesian networks with sharpened posterior estimates perform comparably to prior existing methods and show potential worthy of further exploration.

Edward Ellis, Andrew Bulpitt, Nasim Parsa et al.

Ultrasound (US) imaging is clinically invaluable due to its noninvasive and safe nature. However, interpreting US images is challenging, requires significant expertise, and time, and is often prone to errors. Deep learning offers assistive solutions such as segmentation. Supervised methods rely on large, high-quality, and consistently labeled datasets, which are challenging to curate. Moreover, these methods tend to underperform on out-of-distribution data, limiting their clinical utility. Self-supervised learning (SSL) has emerged as a promising alternative, leveraging unlabeled data to enhance model performance and generalisability. We introduce a contrastive SSL approach tailored for B-mode US images, incorporating a novel Relation Contrastive Loss (RCL). RCL encourages learning of distinct features by differentiating positive and negative sample pairs through a learnable metric. Additionally, we propose spatial and frequency-based augmentation strategies for the representation learning on US images. Our approach significantly outperforms traditional supervised segmentation methods across three public breast US datasets, particularly in data-limited scenarios. Notable improvements on the Dice similarity metric include a 4% increase on 20% and 50% of the BUSI dataset, nearly 6% and 9% improvements on 20% and 50% of the BrEaST dataset, and 6.4% and 3.7% improvements on 20% and 50% of the UDIAT dataset, respectively. Furthermore, we demonstrate superior generalisability on the out-of-distribution UDIAT dataset with performance boosts of 20.6% and 13.6% compared to the supervised baseline using 20% and 50% of the BUSI and BrEaST training data, respectively. Our research highlights that domain-inspired SSL can improve US segmentation, especially under data-limited conditions.

Edward Ellis, Robert Mendel, Andrew Bulpitt et al.

Acquiring and annotating large datasets in ultrasound imaging is challenging due to low contrast, high noise, and susceptibility to artefacts. This process requires significant time and clinical expertise. Self-supervised learning (SSL) offers a promising solution by leveraging unlabelled data to learn useful representations, enabling improved segmentation performance when annotated data is limited. Recent state-of-the-art developments in SSL for video data include V-JEPA, a framework solely based on feature prediction, avoiding pixel level reconstruction or negative samples. We hypothesise that V-JEPA is well-suited to ultrasound imaging, as it is less sensitive to noisy pixel-level detail while effectively leveraging temporal information. To the best of our knowledge, this is the first study to adopt V-JEPA for ultrasound video data. Similar to other patch-based masking SSL techniques such as VideoMAE, V-JEPA is well-suited to ViT-based models. However, ViTs can underperform on small medical datasets due to lack of inductive biases, limited spatial locality and absence of hierarchical feature learning. To improve locality understanding, we propose a novel 3D localisation auxiliary task to improve locality in ViT representations during V-JEPA pre-training. Our results show V-JEPA with our auxiliary task improves segmentation performance significantly across various frozen encoder configurations, with gains up to 3.4\% using 100\% and up to 8.35\% using only 10\% of the training data.

Deshan Gong, Zhanxing Zhu, Andrew J. Bulpitt et al.

Differentiable physics modeling combines physics models with gradient-based learning to provide model explicability and data efficiency. It has been used to learn dynamics, solve inverse problems and facilitate design, and is at its inception of impact. Current successes have concentrated on general physics models such as rigid bodies, deformable sheets, etc., assuming relatively simple structures and forces. Their granularity is intrinsically coarse and therefore incapable of modelling complex physical phenomena. Fine-grained models are still to be developed to incorporate sophisticated material structures and force interactions with gradient-based learning. Following this motivation, we propose a new differentiable fabrics model for composite materials such as cloths, where we dive into the granularity of yarns and model individual yarn physics and yarn-to-yarn interactions. To this end, we propose several differentiable forces, whose counterparts in empirical physics are indifferentiable, to facilitate gradient-based learning. These forces, albeit applied to cloths, are ubiquitous in various physical systems. Through comprehensive evaluation and comparison, we demonstrate our model's explicability in learning meaningful physical parameters, versatility in incorporating complex physical structures and heterogeneous materials, data-efficiency in learning, and high-fidelity in capturing subtle dynamics.