Shuchang Xu

h-index11
2papers
459citations

2 Papers

3.7CVSep 30, 2024
SurgPETL: Parameter-Efficient Image-to-Surgical-Video Transfer Learning for Surgical Phase Recognition

Shu Yang, Zhiyuan Cai, Luyang Luo et al.

Capitalizing on image-level pre-trained models for various downstream tasks has recently emerged with promising performance. However, the paradigm of "image pre-training followed by video fine-tuning" for high-dimensional video data inevitably poses significant performance bottlenecks. Furthermore, in the medical domain, many surgical video tasks encounter additional challenges posed by the limited availability of video data and the necessity for comprehensive spatial-temporal modeling. Recently, Parameter-Efficient Image-to-Video Transfer Learning has emerged as an efficient and effective paradigm for video action recognition tasks, which employs image-level pre-trained models with promising feature transferability and involves cross-modality temporal modeling with minimal fine-tuning. Nevertheless, the effectiveness and generalizability of this paradigm within intricate surgical domain remain unexplored. In this paper, we delve into a novel problem of efficiently adapting image-level pre-trained models to specialize in fine-grained surgical phase recognition, termed as Parameter-Efficient Image-to-Surgical-Video Transfer Learning. Firstly, we develop a parameter-efficient transfer learning benchmark SurgPETL for surgical phase recognition, and conduct extensive experiments with three advanced methods based on ViTs of two distinct scales pre-trained on five large-scale natural and medical datasets. Then, we introduce the Spatial-Temporal Adaptation module, integrating a standard spatial adapter with a novel temporal adapter to capture detailed spatial features and establish connections across temporal sequences for robust spatial-temporal modeling. Extensive experiments on three challenging datasets spanning various surgical procedures demonstrate the effectiveness of SurgPETL with STA.

4.1LGApr 3, 2025
SCMPPI: Supervised Contrastive Multimodal Framework for Predicting Protein-Protein Interactions

Shengrui XU, Tianchi Lu, Zikun Wang et al.

Protein-protein interaction (PPI) prediction plays a pivotal role in deciphering cellular functions and disease mechanisms. To address the limitations of traditional experimental methods and existing computational approaches in cross-modal feature fusion and false-negative suppression, we propose SCMPPI-a novel supervised contrastive multimodal framework. By effectively integrating sequence-based features (AAC, DPC, ESMC-CKSAAP) with network topology (Node2Vec embeddings) and incorporating an enhanced contrastive learning strategy with negative sample filtering, SCMPPI achieves superior prediction performance. Extensive experiments on eight benchmark datasets demonstrate its state-of-the-art accuracy(98.13%) and AUC(99.69%), along with excellent cross-species generalization (AUC>99%). Successful applications in CD9 networks, Wnt pathway analysis, and cancer-specific networks further highlight its potential for disease target discovery, establishing SCMPPI as a powerful tool for multimodal biological data analysis.