Abdul Rehman Khan

Zunaira Rauf, Abdul Rehman Khan, Asifullah Khan

Accurate nuclei segmentation is an essential foundation for various applications in computational pathology, including cancer diagnosis and treatment planning. Even slight variations in nuclei representations can significantly impact these downstream tasks. However, achieving accurate segmentation remains challenging due to factors like clustered nuclei, high intra-class variability in size and shape, resemblance to other cells, and color or contrast variations between nuclei and background. Despite the extensive utilization of Convolutional Neural Networks (CNNs) in medical image segmentation, they may have trouble capturing long-range dependencies crucial for accurate nuclei delineation. Transformers address this limitation but might miss essential low-level features. To overcome these limitations, we utilized CNN-Transformer-based techniques for nuclei segmentation in H&E stained histology images. In this work, we proposed two CNN-Transformer architectures, Nuclei Hybrid Vision Transformer (NucleiHVT) and Channel Boosted Nuclei Hybrid Vision Transformer (CB-NucleiHVT), that leverage the strengths of both CNNs and Transformers to effectively learn nuclei boundaries in multi-organ histology images. The first architecture, NucleiHVT is inspired by the UNet architecture and incorporates the dual attention mechanism to capture both multi-level and multi-scale context effectively. The CB-NucleiHVT network, on the other hand, utilizes the concept of channel boosting to learn diverse feature spaces, enhancing the model's ability to distinguish subtle variations in nuclei characteristics. Detailed evaluation of two medical image segmentation datasets shows that the proposed architectures outperform existing CNN-based, Transformer-based, and hybrid methods. The proposed networks demonstrated effective results both in terms of quantitative metrics, and qualitative visual assessment.

Muhammad Usman, M Husnain Shahid, Maheen Ejaz et al.

Jet tagging is an essential categorization problem in high energy physics. In recent times, Deep Learning has not only risen to the challenge of jet tagging but also significantly improved its performance. In this article, we proposed an idea of a new architecture, Particle Multi-Axis transformer (ParMAT) which is a modified version of Particle transformer (ParT). ParMAT contains local and global spatial interactions within a single unit which improves its ability to handle various input lengths. We trained our model on JETCLASS, a publicly available large dataset that contains 100M jets of 10 different classes of particles. By integrating a parallel attention mechanism and pairwise interactions of particles in the attention mechanism, ParMAT achieves robustness and higher accuracy over the ParT and ParticleNet. The scalability of the model to huge datasets and its ability to automatically extract essential features demonstrate its potential for enhancing jet tagging.