Liqun Shan

Sai Venkatesh Chilukoti, Imran Hossen Md, Liqun Shan et al.

Based on global genomic status, the cancer tumor is classified as Microsatellite Instable (MSI) and Microsatellite Stable (MSS). Immunotherapy is used to diagnose MSI, whereas radiation and chemotherapy are used for MSS. Therefore, it is significant to classify a gastro-intestinal (GI) cancer tumor into MSI vs. MSS to provide appropriate treatment. The existing literature showed that deep learning could directly predict the class of GI cancer tumors from histological images. However, deep learning (DL) models are susceptible to various threats, including membership inference attacks, model extraction attacks, etc. These attacks render the use of DL models impractical in real-world scenarios. To make the DL models useful and maintain privacy, we integrate differential privacy (DP) with DL. In particular, this paper aims to predict the state of GI cancer while preserving the privacy of sensitive data. We fine-tuned the Normalizer Free Net (NF-Net) model. We obtained an accuracy of 88.98\% without DP to predict (GI) cancer status. When we fine-tuned the NF-Net using DP-AdamW and adaptive DP-AdamW, we got accuracies of 74.58% and 76.48%, respectively. Moreover, we investigate the Weighted Random Sampler (WRS) and Class weighting (CW) to solve the data imbalance. We also evaluated and analyzed the DP algorithms in different settings.

Sai Venkatesh Chilukoti, Md Imran Hossen, Liqun Shan et al.

Differentially Private Stochastic Gradient Descent (DP-SGD) has become a widely used technique for safeguarding sensitive information in deep learning applications. Unfortunately, DPSGD's per-sample gradient clipping and uniform noise addition during training can significantly degrade model utility and fairness. We observe that the latest DP-SGD-Global-Adapt's average gradient norm is the same throughout the training. Even when it is integrated with the existing linear decay noise multiplier, it has little or no advantage. Moreover, we notice that its upper clipping threshold increases exponentially towards the end of training, potentially impacting the models convergence. Other algorithms, DP-PSAC, Auto-S, DP-SGD-Global, and DP-F, have utility and fairness that are similar to or worse than DP-SGD, as demonstrated in experiments. To overcome these problems and improve utility and fairness, we developed the DP-SGD-Global-Adapt-V2-S. It has a step-decay noise multiplier and an upper clipping threshold that is also decayed step-wise. DP-SGD-Global-Adapt-V2-S with a privacy budget ($ε$) of 1 improves accuracy by 0.9795\%, 0.6786\%, and 4.0130\% in MNIST, CIFAR10, and CIFAR100, respectively. It also reduces the privacy cost gap ($π$) by 89.8332% and 60.5541% in unbalanced MNIST and Thinwall datasets, respectively. Finally, we develop mathematical expressions to compute the privacy budget using truncated concentrated differential privacy (tCDP) for DP-SGD-Global-Adapt-V2-T and DP-SGD-Global-Adapt-V2-S.

Vijay Srinivas Tida, Md Imran Hossen, Liqun Shan et al.

The optimization of the transpose convolution layer for deep learning applications is achieved with the kernel segregation mechanism. However, kernel segregation has disadvantages, such as computing extra elements to obtain the output feature map with odd dimensions while launching a thread. To mitigate this problem, we introduce a unified kernel segregation approach that limits the usage of memory and computational resources by employing one unified kernel to execute four sub-kernels. The findings reveal that the suggested approach achieves an average computational speedup of 2.03x (3.89x) when tested on specific datasets with an RTX 2070 GPU (Intel Xeon CPU). The ablation study shows an average computational speedup of 3.5x when evaluating the transpose convolution layers from well-known Generative Adversarial Networks (GANs). The implementation of the proposed method for the transpose convolution layers in the EB-GAN model demonstrates significant memory savings of up to 35 MB.

Md Imran Hossen, Sai Venkatesh Chilukoti, Liqun Shan et al.

The primary goal of this project is to develop privacy-preserving machine learning model training techniques for fNIRS data. This project will build a local model in a centralized setting with both differential privacy (DP) and certified robustness. It will also explore collaborative federated learning to train a shared model between multiple clients without sharing local fNIRS datasets. To prevent unintentional private information leakage of such clients' private datasets, we will also implement DP in the federated learning setting.