James Wingate

Dimitrios Kollias, Anastasios Arsenos, James Wingate et al.

This paper presents a new approach for effective segmentation of images that can be integrated into any model and methodology; the paradigm that we choose is classification of medical images (3-D chest CT scans) for Covid-19 detection. Our approach includes a combination of vision-language models that segment the CT scans, which are then fed to a deep neural architecture, named RACNet, for Covid-19 detection. In particular, a novel framework, named SAM2CLIP2SAM, is introduced for segmentation that leverages the strengths of both Segment Anything Model (SAM) and Contrastive Language-Image Pre-Training (CLIP) to accurately segment the right and left lungs in CT scans, subsequently feeding these segmented outputs into RACNet for classification of COVID-19 and non-COVID-19 cases. At first, SAM produces multiple part-based segmentation masks for each slice in the CT scan; then CLIP selects only the masks that are associated with the regions of interest (ROIs), i.e., the right and left lungs; finally SAM is given these ROIs as prompts and generates the final segmentation mask for the lungs. Experiments are presented across two Covid-19 annotated databases which illustrate the improved performance obtained when our method has been used for segmentation of the CT scans.

D. Kollias, N. Bouas, Y. Vlaxos et al.

The paper presents a novel deep learning approach, which extracts latent information from trained Deep Neural Networks (DNNs) and derives concise representations that are analyzed in an effective, unified way for prediction purposes. It is well known that DNNs are capable of analyzing complex data; however, they lack transparency in their decision making, in the sense that it is not straightforward to justify their prediction, or to visualize the features on which the decision was based. Moreover, they generally require large amounts of data in order to learn and become able to adapt to different environments. This makes their use difficult in healthcare, where trust and personalization are key issues. Transparency combined with high prediction accuracy are the targeted goals of the proposed approach. It includes both supervised DNN training and unsupervised learning of latent variables extracted from the trained DNNs. Domain Adaptation from multiple sources is also presented as an extension, where the extracted latent variable representations are used to generate predictions in other, non-annotated, environments. Successful application is illustrated through a large experimental study in various fields: prediction of Parkinson's disease from MRI and DaTScans; prediction of COVID-19 and pneumonia from CT scans and X-rays; optical character verification in retail food packaging.

James Wingate, Ilianna Kollia, Luc Bidaut et al.

The paper presents a novel approach, based on deep learning, for diagnosis of Parkinson's disease through medical imaging. The approach includes analysis and use of the knowledge extracted by Deep Convolutional and Recurrent Neural Networks (DNNs) when trained with medical images, such as Magnetic Resonance Images and DaTscans. Internal representations of the trained DNNs constitute the extracted knowledge which is used in a transfer learning and domain adaptation manner, so as to create a unified framework for prediction of Parkinson's across different medical environments. A large experimental study is presented illustrating the ability of the proposed approach to effectively predict Parkinson's, using different medical image sets from real environments.