Ricardo J. Araújo

R. J. Araújo, J. S. Cardoso, H. P. Oliveira

Blood vessel segmentation is one of the most studied topics in computer vision, due to its relevance in daily clinical practice. Despite the evolution the field has been facing, especially after the dawn of deep learning, important challenges are still not solved. One of them concerns the consistency of the topological properties of the vascular trees, given that the best performing methodologies do not directly penalize mistakes such as broken segments and end up producing predictions with disconnected trees. This is particularly relevant in graph-like structures, such as blood vessel trees, given that it puts at risk the characterization steps that follow the segmentation task. In this paper, we propose a similarity index which captures the topological consistency of the predicted segmentations having as reference the ground truth. We also design a novel loss function based on the morphological closing operator and show how it allows to learn deep neural network models which produce more topologically coherent masks. Our experiments target well known retinal benchmarks and a coronary angiogram database.

Ricardo J. Araújo, Vera Garrido, Catarina A. Baraças et al.

The deep inferior epigastric artery perforator (DIEAP) flap is the most common free flap used for breast reconstruction after a mastectomy. It makes use of the skin and fat of the lower abdomen to build a new breast mound either at the same time of the mastectomy or in a second surgery. This operation requires preoperative imaging studies to evaluate the branches - the perforators - that irrigate the tissue that will be used to reconstruct the breast mound. These branches will support tissue viability after the microsurgical ligation of the inferior epigastric vessels to the receptor vessels in the thorax. Usually through a Computed Tomography Angiography (CTA), each perforator, diameter and direction is manually identified by the imaging team, who will subsequently draw a map for the identification of the best vascular support for the reconstruction. In the current work we propose a semi-automatic methodology that aims at reducing the time and subjectivity inherent to the manual annotation. In 21 CTAs from patients proposed for breast reconstruction with DIEAP flaps, the subcutaneous region of each perforator was extracted, by means of a tracking procedure, whereas the intramuscular portion was detected through a minimum cost approach. Both were subsequently compared with the radiologist manual annotation. Results showed that the semi-automatic procedure was able to correctly detect the course of the DIEAPs with a minimum error (average error of 0.64 mm and 0.50 mm regarding the extraction of subcutaneous and intramuscular paths, respectively). The objective methodology is a promising tool in the automatic detection of perforators in CTA and can contribute to spare human resources and reduce subjectivity in the aforementioned task.