2.0IVJan 23, 2020
A One-Shot Learning Framework for Assessment of Fibrillar Collagen from Second Harmonic Generation Images of an Infarcted MyocardiumQun Liu, Supratik Mukhopadhyay, Maria Ximena Bastidas Rodriguez et al.
Myocardial infarction (MI) is a scientific term that refers to heart attack. In this study, we infer highly relevant second harmonic generation (SHG) cues from collagen fibers exhibiting highly non-centrosymmetric assembly together with two-photon excited cellular autofluorescence in infarcted mouse heart to quantitatively probe fibrosis, especially targeted at an early stage after MI. We present a robust one-shot machine learning algorithm that enables determination of 2D assembly of collagen with high spatial resolution along with its structural arrangement in heart tissues post-MI with spectral specificity and sensitivity. Detection, evaluation, and precise quantification of fibrosis extent at early stage would guide one to develop treatment therapies that may prevent further progression and determine heart transplant needs for patient survival.
3.8CVDec 6, 2016
Core Sampling Framework for Pixel ClassificationManohar Karki, Robert DiBiano, Saikat Basu et al.
The intermediate map responses of a Convolutional Neural Network (CNN) contain information about an image that can be used to extract contextual knowledge about it. In this paper, we present a core sampling framework that is able to use these activation maps from several layers as features to another neural network using transfer learning to provide an understanding of an input image. Our framework creates a representation that combines features from the test data and the contextual knowledge gained from the responses of a pretrained network, processes it and feeds it to a separate Deep Belief Network. We use this representation to extract more information from an image at the pixel level, hence gaining understanding of the whole image. We experimentally demonstrate the usefulness of our framework using a pretrained VGG-16 model to perform segmentation on the BAERI dataset of Synthetic Aperture Radar(SAR) imagery and the CAMVID dataset.