Thomas Lai

h-index3
2papers
20citations

2 Papers

9.8LGOct 18, 2023
Open-Set Multivariate Time-Series Anomaly Detection

Thomas Lai, Thi Kieu Khanh Ho, Narges Armanfard

Numerous methods for time-series anomaly detection (TSAD) have emerged in recent years, most of which are unsupervised and assume that only normal samples are available during the training phase, due to the challenge of obtaining abnormal data in real-world scenarios. Still, limited samples of abnormal data are often available, albeit they are far from representative of all possible anomalies. Supervised methods can be utilized to classify normal and seen anomalies, but they tend to overfit to the seen anomalies present during training, hence, they fail to generalize to unseen anomalies. We propose the first algorithm to address the open-set TSAD problem, called Multivariate Open-Set Time-Series Anomaly Detector (MOSAD), that leverages only a few shots of labeled anomalies during the training phase in order to achieve superior anomaly detection performance compared to both supervised and unsupervised TSAD algorithms. MOSAD is a novel multi-head TSAD framework with a shared representation space and specialized heads, including the Generative head, the Discriminative head, and the Anomaly-Aware Contrastive head. The latter produces a superior representation space for anomaly detection compared to conventional supervised contrastive learning. Extensive experiments on three real-world datasets establish MOSAD as a new state-of-the-art in the TSAD field.

10.8LGJun 21
Foundation Models for Epileptogenic Zone Identification in Drug-Resistant Epilepsy

Thi Kieu Khanh Ho, Thomas Lai, Petr Klimes et al.

Accurate identification of the epileptogenic zone (EZ) is essential for seizure freedom after resective surgery in drug-resistant epilepsy, yet seizure freedom rates remain below 50%. We developed EpiiSLM, a dual foundation model system for EZ identification with stereo-electroencephalography (sEEG), by training a signal foundation model on 104,990 minutes of sEEG recordings from the Montreal Neurological Institute & Hospital, while leveraging all recordings regardless of surgical outcome and anchoring EZ biomarker extraction on non-epileptic signals. A language foundation model then integrates sEEG-derived outputs with multimodal clinical information to produce interpretable predictions. Under leave-one-patient-out evaluation, EpiiSLM achieved 0.978 contact-level positive predictive value (PPV), outperforming the seizure onset zone(SOZ)-as-EZ baseline by 15.1% (p < 0.05), and 100% region-level accuracy; on an external dataset, EpiiSLM achieved 0.857 contact-level PPV. EpiiSLM requires only one night of interictal sleep data, suggesting potential to reduce invasive sEEG monitoring duration and improve surgical outcomes.