James Kinross

Kaizhe Jin, Adrian Rubio-Solis, Ravi Naik et al.

The operating room (OR) is a dynamic and complex environment consisting of a multidisciplinary team working together in a high take environment to provide safe and efficient patient care. Additionally, surgeons are frequently exposed to multiple psycho-organisational stressors that may cause negative repercussions on their immediate technical performance and long-term health. Many factors can therefore contribute to increasing the Cognitive Workload (CWL) such as temporal pressures, unfamiliar anatomy or distractions in the OR. In this paper, a cascade of two machine learning approaches is suggested for the multimodal recognition of CWL in four different surgical task conditions. Firstly, a model based on the concept of transfer learning is used to identify if a surgeon is experiencing any CWL. Secondly, a Convolutional Neural Network (CNN) uses this information to identify different degrees of CWL associated to each surgical task. The suggested multimodal approach considers adjacent signals from electroencephalogram (EEG), functional near-infrared spectroscopy (fNIRS) and eye pupil diameter. The concatenation of signals allows complex correlations in terms of time (temporal) and channel location (spatial). Data collection was performed by a Multi-sensing AI Environment for Surgical Task & Role Optimisation platform (MAESTRO) developed at the Hamlyn Centre, Imperial College London. To compare the performance of the proposed methodology, a number of state-of-art machine learning techniques have been implemented. The tests show that the proposed model has a precision of 93%.

Antonio Rago, Bence Palfi, Purin Sukpanichnant et al.

AI-driven tools for healthcare are widely acknowledged as potentially beneficial to health practitioners and patients, e.g. the QCancer regression tool for cancer risk prediction. However, for these tools to be trusted, they need to be supplemented with explanations. We examine how explanations' content and format affect user comprehension and trust when explaining QCancer's predictions. Regarding content, we deploy the SHAP and Occlusion-1 explanation methods. Regarding format, we present SHAP explanations, conventionally, as charts (SC) and Occlusion-1 explanations as charts (OC) as well as text (OT), to which their simpler nature lends itself. We conduct experiments with two sets of stakeholders: the general public (representing patients) and medical students (representing healthcare practitioners). Our experiments showed higher subjective comprehension and trust for Occlusion-1 over SHAP explanations based on content. However, when controlling for format, only OT outperformed SC, suggesting this trend is driven by preferences for text. Other findings corroborated that explanation format, rather than content, is often the critical factor.

Lihu Chen, Shuojie Fu, Gabriel Freedman et al.

A significant and growing number of published scientific articles is found to involve fraudulent practices, posing a serious threat to the credibility and safety of research in fields such as medicine. We propose Pub-Guard-LLM, the first large language model-based system tailored to fraud detection of biomedical scientific articles. We provide three application modes for deploying Pub-Guard-LLM: vanilla reasoning, retrieval-augmented generation, and multi-agent debate. Each mode allows for textual explanations of predictions. To assess the performance of our system, we introduce an open-source benchmark, PubMed Retraction, comprising over 11K real-world biomedical articles, including metadata and retraction labels. We show that, across all modes, Pub-Guard-LLM consistently surpasses the performance of various baselines and provides more reliable explanations, namely explanations which are deemed more relevant and coherent than those generated by the baselines when evaluated by multiple assessment methods. By enhancing both detection performance and explainability in scientific fraud detection, Pub-Guard-LLM contributes to safeguarding research integrity with a novel, effective, open-source tool.