Aggelos K. Katsaggelos

Amil Dravid, Florian Schiffers, Boqing Gong et al.

Despite the surge of deep learning in the past decade, some users are skeptical to deploy these models in practice due to their black-box nature. Specifically, in the medical space where there are severe potential repercussions, we need to develop methods to gain confidence in the models' decisions. To this end, we propose a novel medical imaging generative adversarial framework, medXGAN (medical eXplanation GAN), to visually explain what a medical classifier focuses on in its binary predictions. By encoding domain knowledge of medical images, we are able to disentangle anatomical structure and pathology, leading to fine-grained visualization through latent interpolation. Furthermore, we optimize the latent space such that interpolation explains how the features contribute to the classifier's output. Our method outperforms baselines such as Gradient-Weighted Class Activation Mapping (Grad-CAM) and Integrated Gradients in localization and explanatory ability. Additionally, a combination of the medXGAN with Integrated Gradients can yield explanations more robust to noise. The code is available at: https://avdravid.github.io/medXGAN_page/.

S. Derin Babacan, Martin Luessi, Rafael Molina et al.

Recovery of low-rank matrices has recently seen significant activity in many areas of science and engineering, motivated by recent theoretical results for exact reconstruction guarantees and interesting practical applications. A number of methods have been developed for this recovery problem. However, a principled method for choosing the unknown target rank is generally not provided. In this paper, we present novel recovery algorithms for estimating low-rank matrices in matrix completion and robust principal component analysis based on sparse Bayesian learning (SBL) principles. Starting from a matrix factorization formulation and enforcing the low-rank constraint in the estimates as a sparsity constraint, we develop an approach that is very effective in determining the correct rank while providing high recovery performance. We provide connections with existing methods in other similar problems and empirical results and comparisons with current state-of-the-art methods that illustrate the effectiveness of this approach.

Tom Liu, Hui Lin, Aggelos K. Katsaggelos et al.

Coronary angiography remains the gold standard for diagnosis of coronary artery disease, the most common cause of death worldwide. While this procedure is performed more than 2 million times annually, there remain few methods for fast and accurate automated measurement of disease and localization of coronary anatomy. Here, we present our solution to the Automatic Region-based Coronary Artery Disease diagnostics using X-ray angiography images (ARCADE) challenge held at MICCAI 2023. For the artery segmentation task, our three-stage approach combines preprocessing and feature selection by classical computer vision to enhance vessel contrast, followed by an ensemble model based on YOLOv8 to propose possible vessel candidates by generating a vessel map. A final segmentation is based on a logic-based approach to reconstruct the coronary tree in a graph-based sorting method. Our entry to the ARCADE challenge placed 3rd overall. Using the official metric for evaluation, we achieved an F1 score of 0.422 and 0.4289 on the validation and hold-out sets respectively.

Semih Barutcu, Doğa Gürsoy, Aggelos K. Katsaggelos

Ptychography is a well-established coherent diffraction imaging technique that enables non-invasive imaging of samples at a nanometer scale. It has been extensively used in various areas such as the defense industry or materials science. One major limitation of ptychography is the long data acquisition time due to mechanical scanning of the sample; therefore, approaches to reduce the scan points are highly desired. However, reconstructions with less number of scan points lead to imaging artifacts and significant distortions, hindering a quantitative evaluation of the results. To address this bottleneck, we propose a generative model combining deep image priors with deep generative priors. The self-training approach optimizes the deep generative neural network to create a solution for a given dataset. We complement our approach with a prior acquired from a previously trained discriminator network to avoid a possible divergence from the desired output caused by the noise in the measurements. We also suggest using the total variation as a complementary before combat artifacts due to measurement noise. We analyze our approach with numerical experiments through different probe overlap percentages and varying noise levels. We also demonstrate improved reconstruction accuracy compared to the state-of-the-art method and discuss the advantages and disadvantages of our approach.

Jiaqi Guo, Santiago Lopez-Tapia, Wing Shun Li et al.

Computed tomography is a widely used imaging modality with applications ranging from medical imaging to material analysis. One major challenge arises from the lack of scanning information at certain angles, resulting in distortion or artifacts in the reconstructed images. This is referred to as the Limited Angle Computed Tomography (LACT) reconstruction problem. To address this problem, we propose the use of Residual Null-Space Diffusion Stochastic Differential Equations (RN-SDEs), which are a variant of diffusion models that characterize the diffusion process with mean-reverting (MR) stochastic differential equations. To demonstrate the generalizability of RN-SDEs, we conducted experiments with two different LACT datasets, ChromSTEM and C4KC-KiTS. Through extensive experiments, we demonstrate that by leveraging learned MR-SDEs as a prior and emphasizing data consistency using Range-Null Space Decomposition (RNSD) based rectification, we can recover high-quality images from severely degraded ones and achieve state-of-the-art performance in most LACT tasks. Additionally, we present a quantitative comparison of RN-SDE with other networks, in terms of computational complexity and runtime efficiency, highlighting the superior effectiveness of our proposed approach.

Yunan Wu, Francisco M. Castro-Macías, Pablo Morales-Álvarez et al.

Multiple Instance Learning (MIL) has been widely applied to medical imaging diagnosis, where bag labels are known and instance labels inside bags are unknown. Traditional MIL assumes that instances in each bag are independent samples from a given distribution. However, instances are often spatially or sequentially ordered, and one would expect similar diagnostic importance for neighboring instances. To address this, in this study, we propose a smooth attention deep MIL (SA-DMIL) model. Smoothness is achieved by the introduction of first and second order constraints on the latent function encoding the attention paid to each instance in a bag. The method is applied to the detection of intracranial hemorrhage (ICH) on head CT scans. The results show that this novel SA-DMIL: (a) achieves better performance than the non-smooth attention MIL at both scan (bag) and slice (instance) levels; (b) learns spatial dependencies between slices; and (c) outperforms current state-of-the-art MIL methods on the same ICH test set.

Xinyi Wu, Haohong Wang, Aggelos K. Katsaggelos

User-generated cinematic creations are gaining popularity as our daily entertainment, yet it is a challenge to master cinematography for producing immersive contents. Many existing automatic methods focus on roughly controlling predefined shot types or movement patterns, which struggle to engage viewers with the circumstances of the actor. Real-world cinematographic rules show that directors can create immersion by comprehensively synchronizing the camera with the actor. Inspired by this strategy, we propose a deep camera control framework that enables actor-camera synchronization in three aspects, considering frame aesthetics, spatial action, and emotional status in the 3D virtual stage. Following rule-of-thirds, our framework first modifies the initial camera placement to position the actor aesthetically. This adjustment is facilitated by a self-supervised adjustor that analyzes frame composition via camera projection. We then design a GAN model that can adversarially synthesize fine-grained camera movement based on the physical action and psychological state of the actor, using an encoder-decoder generator to map kinematics and emotional variables into camera trajectories. Moreover, we incorporate a regularizer to align the generated stylistic variances with specific emotional categories and intensities. The experimental results show that our proposed method yields immersive cinematic videos of high quality, both quantitatively and qualitatively. Live examples can be found in the supplementary video.

Nicholas X. Wang, Neel V. Parpia, Aaryan D. Parikh et al.

Intuitive learning is crucial for developing deep conceptual understanding, especially in STEM education, where students often struggle with abstract and interconnected concepts. Automatic question generation has become an effective strategy for personalized and adaptive learning. However, its effectiveness is hindered by hallucinations in large language models (LLMs), which may generate factually incorrect, ambiguous, or pedagogically inconsistent questions. To address this issue, we propose a novel framework that combines causal-graph-guided Chain-of-Thought (CoT) reasoning with a multi-agent LLM architecture. This approach ensures the generation of accurate, meaningful, and curriculum-aligned questions. Causal graphs provide an explicit representation of domain knowledge, while CoT reasoning facilitates a structured, step-by-step traversal of related concepts. Dedicated LLM agents are assigned specific tasks such as graph pathfinding, reasoning, validation, and output, all working within domain constraints. A dual validation mechanism-at both the conceptual and output stages-greatly reduces hallucinations. Experimental results demonstrate up to a 70% improvement in quality compared to reference methods and yielded highly favorable outcomes in subjective evaluations.

Shamika Likhite, Santiago López-Tapia, Aggelos K. Katsaggelos

Motion blur, caused by relative movement between camera and scene during exposure, significantly degrades image quality and impairs downstream computer vision tasks such as object detection, tracking, and recognition in dynamic environments. While deep learning-based motion deblurring methods have achieved remarkable progress, existing approaches face fundamental challenges in capturing the long-range spatial dependencies inherent in motion blur patterns. Traditional convolutional methods rely on limited receptive fields and require extremely deep networks to model global spatial relationships. These limitations motivate the need for alternative approaches that incorporate physical priors to guide feature evolution during restoration. In this paper, we propose a progressive training framework that integrates physics-informed PDE dynamics into state-of-the-art restoration architectures. By leveraging advection-diffusion equations to model feature evolution, our approach naturally captures the directional flow characteristics of motion blur while enabling principled global spatial modeling. Our PDE-enhanced deblurring models achieve superior restoration quality with minimal overhead, adding only approximately 1\% to inference GMACs while providing consistent improvements in perceptual quality across multiple state-of-the-art architectures. Comprehensive experiments on standard motion deblurring benchmarks demonstrate that our physics-informed approach improves PSNR and SSIM significantly across four diverse architectures, including FFTformer, NAFNet, Restormer, and Stripformer. These results validate that incorporating mathematical physics principles through PDE-based global layers can enhance deep learning-based image restoration, establishing a promising direction for physics-informed neural network design in computer vision applications.

Zhihao Huang, Santiago Lopez-Tapia, Aggelos K. Katsaggelos

Video deblurring is a challenging task that aims to recover sharp sequences from blur and noisy observations. The image-formation model plays a crucial role in traditional model-based methods, constraining the possible solutions. However, this is only the case for some deep learning-based methods. Despite deep-learning models achieving better results, traditional model-based methods remain widely popular due to their flexibility. An increasing number of scholars combine the two to achieve better deblurring performance. This paper proposes introducing knowledge of the image-formation model into a deep learning network by using the pseudo-inverse of the blur. We use a deep network to fit the blurring and estimate pseudo-inverse. Then, we use this estimation, combined with a variational deep-learning network, to deblur the video sequence. Notably, our experimental results demonstrate that such modifications can significantly improve the performance of deep learning models for video deblurring. Furthermore, our experiments on different datasets achieved notable performance improvements, proving that our proposed method can generalize to different scenarios and cameras.

Yunan Wu, Amil Dravid, Ramsey Michael Wehbe et al.

Propose: To present DeepCOVID-Fuse, a deep learning fusion model to predict risk levels in patients with confirmed coronavirus disease 2019 (COVID-19) and to evaluate the performance of pre-trained fusion models on full or partial combination of chest x-ray (CXRs) or chest radiograph and clinical variables. Materials and Methods: The initial CXRs, clinical variables and outcomes (i.e., mortality, intubation, hospital length of stay, ICU admission) were collected from February 2020 to April 2020 with reverse-transcription polymerase chain reaction (RT-PCR) test results as the reference standard. The risk level was determined by the outcome. The fusion model was trained on 1657 patients (Age: 58.30 +/- 17.74; Female: 807) and validated on 428 patients (56.41 +/- 17.03; 190) from Northwestern Memorial HealthCare system and was tested on 439 patients (56.51 +/- 17.78; 205) from a single holdout hospital. Performance of pre-trained fusion models on full or partial modalities were compared on the test set using the DeLong test for the area under the receiver operating characteristic curve (AUC) and the McNemar test for accuracy, precision, recall and F1. Results: The accuracy of DeepCOVID-Fuse trained on CXRs and clinical variables is 0.658, with an AUC of 0.842, which significantly outperformed (p < 0.05) models trained only on CXRs with an accuracy of 0.621 and AUC of 0.807 and only on clinical variables with an accuracy of 0.440 and AUC of 0.502. The pre-trained fusion model with only CXRs as input increases accuracy to 0.632 and AUC to 0.813 and with only clinical variables as input increases accuracy to 0.539 and AUC to 0.733. Conclusion: The fusion model learns better feature representations across different modalities during training and achieves good outcome predictions even when only some of the modalities are used in testing.

Semih Barutcu, Aggelos K. Katsaggelos, Doğa Gürsoy

Ptychography is a well-studied phase imaging method that makes non-invasive imaging possible at a nanometer scale. It has developed into a mainstream technique with various applications across a range of areas such as material science or the defense industry. One major drawback of ptychography is the long data acquisition time due to the high overlap requirement between adjacent illumination areas to achieve a reasonable reconstruction. Traditional approaches with reduced overlap between scanning areas result in reconstructions with artifacts. In this paper, we propose complementing sparsely acquired or undersampled data with data sampled from a deep generative network to satisfy the oversampling requirement in ptychography. Because the deep generative network is pre-trained and its output can be computed as we collect data, the experimental data and the time to acquire the data can be reduced. We validate the method by presenting the reconstruction quality compared to the previously proposed and traditional approaches and comment on the strengths and drawbacks of the proposed approach.

Hui Lin, Florian Schiffers, Santiago López-Tapia et al.

Unsupervised domain adaptation (UDA) is essential for medical image segmentation, especially in cross-modality data scenarios. UDA aims to transfer knowledge from a labeled source domain to an unlabeled target domain, thereby reducing the dependency on extensive manual annotations. This paper presents DRL-STNet, a novel framework for cross-modality medical image segmentation that leverages generative adversarial networks (GANs), disentangled representation learning (DRL), and self-training (ST). Our method leverages DRL within a GAN to translate images from the source to the target modality. Then, the segmentation model is initially trained with these translated images and corresponding source labels and then fine-tuned iteratively using a combination of synthetic and real images with pseudo-labels and real labels. The proposed framework exhibits superior performance in abdominal organ segmentation on the FLARE challenge dataset, surpassing state-of-the-art methods by 11.4% in the Dice similarity coefficient and by 13.1% in the Normalized Surface Dice metric, achieving scores of 74.21% and 80.69%, respectively. The average running time is 41 seconds, and the area under the GPU memory-time curve is 11,292 MB. These results indicate the potential of DRL-STNet for enhancing cross-modality medical image segmentation tasks.

Ugur Demir, Debesh Jha, Zheyuan Zhang et al.

Deployments of artificial intelligence in medical diagnostics mandate not just accuracy and efficacy but also trust, emphasizing the need for explainability in machine decisions. The recent trend in automated medical image diagnostics leans towards the deployment of Transformer-based architectures, credited to their impressive capabilities. Since the self-attention feature of transformers contributes towards identifying crucial regions during the classification process, they enhance the trustability of the methods. However, the complex intricacies of these attention mechanisms may fall short of effectively pinpointing the regions of interest directly influencing AI decisions. Our research endeavors to innovate a unique attention block that underscores the correlation between 'regions' rather than 'pixels'. To address this challenge, we introduce an innovative system grounded in prototype learning, featuring an advanced self-attention mechanism that goes beyond conventional ad-hoc visual explanation techniques by offering comprehensible visual insights. A combined quantitative and qualitative methodological approach was used to demonstrate the effectiveness of the proposed method on the large-scale NIH chest X-ray dataset. Experimental results showed that our proposed method offers a promising direction for explainability, which can lead to the development of more trustable systems, which can facilitate easier and rapid adoption of such technology into routine clinics. The code is available at www.github.com/NUBagcilab/r2r_proto.

Yi Li, Yunan Wu, Aggelos K. Katsaggelos

The advancement of The Laser Interferometer Gravitational-Wave Observatory (LIGO) has significantly enhanced the feasibility and reliability of gravitational wave detection. However, LIGO's high sensitivity makes it susceptible to transient noises known as glitches, which necessitate effective differentiation from real gravitational wave signals. Traditional approaches predominantly employ fully supervised or semi-supervised algorithms for the task of glitch classification and clustering. In the future task of identifying and classifying glitches across main and auxiliary channels, it is impractical to build a dataset with manually labeled ground-truth. In addition, the patterns of glitches can vary with time, generating new glitches without manual labels. In response to this challenge, we introduce the Cross-Temporal Spectrogram Autoencoder (CTSAE), a pioneering unsupervised method for the dimensionality reduction and clustering of gravitational wave glitches. CTSAE integrates a novel four-branch autoencoder with a hybrid of Convolutional Neural Networks (CNN) and Vision Transformers (ViT). To further extract features across multi-branches, we introduce a novel multi-branch fusion method using the CLS (Class) token. Our model, trained and evaluated on the GravitySpy O3 dataset on the main channel, demonstrates superior performance in clustering tasks when compared to state-of-the-art semi-supervised learning methods. To the best of our knowledge, CTSAE represents the first unsupervised approach tailored specifically for clustering LIGO data, marking a significant step forward in the field of gravitational wave research. The code of this paper is available at https://github.com/Zod-L/CTSAE

Patrick Koller, Amil V. Dravid, Guido M. Schuster et al.

Robustness has become one of the most critical problems in machine learning (ML). The science of interpreting ML models to understand their behavior and improve their robustness is referred to as explainable artificial intelligence (XAI). One of the state-of-the-art XAI methods for computer vision problems is to generate saliency maps. A saliency map highlights the pixel space of an image that excites the ML model the most. However, this property could be misleading if spurious and salient features are present in overlapping pixel spaces. In this paper, we propose a caption-based XAI method, which integrates a standalone model to be explained into the contrastive language-image pre-training (CLIP) model using a novel network surgery approach. The resulting caption-based XAI model identifies the dominant concept that contributes the most to the models prediction. This explanation minimizes the risk of the standalone model falling for a covariate shift and contributes significantly towards developing robust ML models. Our code is available at https://github.com/patch0816/caption-driven-xai

Michael Iliadis, Haohong Wang, Rafael Molina et al.

In this paper we propose an iterative method to address the face identification problem with block occlusions. Our approach utilizes a robust representation based on two characteristics in order to model contiguous errors (e.g., block occlusion) effectively. The first fits to the errors a distribution described by a tailored loss function. The second describes the error image as having a specific structure (resulting in low-rank in comparison to image size). We will show that this joint characterization is effective for describing errors with spatial continuity. Our approach is computationally efficient due to the utilization of the Alternating Direction Method of Multipliers (ADMM). A special case of our fast iterative algorithm leads to the robust representation method which is normally used to handle non-contiguous errors (e.g., pixel corruption). Extensive results on representative face databases (in constrained and unconstrained environments) document the effectiveness of our method over existing robust representation methods with respect to both identification rates and computational time. Code is available at Github, where you can find implementations of the F-LR-IRNNLS and F-IRNNLS (fast version of the RRC) : https://github.com/miliadis/FIRC

Michael Iliadis, Leonidas Spinoulas, Aggelos K. Katsaggelos

In this work we present a deep learning framework for video compressive sensing. The proposed formulation enables recovery of video frames in a few seconds at significantly improved reconstruction quality compared to previous approaches. Our investigation starts by learning a linear mapping between video sequences and corresponding measured frames which turns out to provide promising results. We then extend the linear formulation to deep fully-connected networks and explore the performance gains using deeper architectures. Our analysis is always driven by the applicability of the proposed framework on existing compressive video architectures. Extensive simulations on several video sequences document the superiority of our approach both quantitatively and qualitatively. Finally, our analysis offers insights into understanding how dataset sizes and number of layers affect reconstruction performance while raising a few points for future investigation. Code is available at Github: https://github.com/miliadis/DeepVideoCS

Jiaqi Guo, Mingzhen Li, Haohong Wang et al.

We study generative super-resolution (SR) in real-world scenarios where content and degradations vary across domains, genres, and segments. For example, images and videos may alternate between text overlays, fast motion, smooth cartoons, and low-light faces, each benefiting from different forms of side information. Existing metadata-guided SR methods typically use a fixed conditioning design, which is suboptimal when useful cues are content dependent and transmission budgets are limited. We propose MetaSR, a Diffusion Transformer (DiT)-based framework that selects and injects task-relevant metadata to guide SR under resource constraints. Specifically, we use the DiT's own VAE and transformer backbone to fuse heterogeneous metadata, and adopt an efficient distillation strategy that enables one-step diffusion inference. Experiments across diverse content buckets and degradation regimes show that MetaSR outperforms reference solutions by up to 1.0~dB PSNR while achieving up to 50\% transmission bitrate saving at matched quality. We assess these gains under a rate--distortion optimization (RDO) framework that jointly accounts for sender-side bitrate and receiver/display quality metrics (e.g., PSNR and SSIM).

Arne Schmidt, Pablo Morales-Álvarez, Lee A. D. Cooper et al.

Active Learning (AL) has the potential to solve a major problem of digital pathology: the efficient acquisition of labeled data for machine learning algorithms. However, existing AL methods often struggle in realistic settings with artifacts, ambiguities, and class imbalances, as commonly seen in the medical field. The lack of precise uncertainty estimations leads to the acquisition of images with a low informative value. To address these challenges, we propose Focused Active Learning (FocAL), which combines a Bayesian Neural Network with Out-of-Distribution detection to estimate different uncertainties for the acquisition function. Specifically, the weighted epistemic uncertainty accounts for the class imbalance, aleatoric uncertainty for ambiguous images, and an OoD score for artifacts. We perform extensive experiments to validate our method on MNIST and the real-world Panda dataset for the classification of prostate cancer. The results confirm that other AL methods are 'distracted' by ambiguities and artifacts which harm the performance. FocAL effectively focuses on the most informative images, avoiding ambiguities and artifacts during acquisition. For both experiments, FocAL outperforms existing AL approaches, reaching a Cohen's kappa of 0.764 with only 0.69% of the labeled Panda data.

Hui Lin, Charilaos Apostolidis, Aggelos K. Katsaggelos

Differences in image quality, lighting conditions, and patient demographics pose challenges to automated glaucoma detection from color fundus photography. Brighteye, a method based on Vision Transformer, is proposed for glaucoma detection and glaucomatous feature classification. Brighteye learns long-range relationships among pixels within large fundus images using a self-attention mechanism. Prior to being input into Brighteye, the optic disc is localized using YOLOv8, and the region of interest (ROI) around the disc center is cropped to ensure alignment with clinical practice. Optic disc detection improves the sensitivity at 95% specificity from 79.20% to 85.70% for glaucoma detection and the Hamming distance from 0.2470 to 0.1250 for glaucomatous feature classification. In the developmental stage of the Justified Referral in AI Glaucoma Screening (JustRAIGS) challenge, the overall outcome secured the fifth position out of 226 entries.

Xijun Wang, Santiago López-Tapia, Aggelos K. Katsaggelos

Atmospheric turbulence, a common phenomenon in daily life, is primarily caused by the uneven heating of the Earth's surface. This phenomenon results in distorted and blurred acquired images or videos and can significantly impact downstream vision tasks, particularly those that rely on capturing clear, stable images or videos from outdoor environments, such as accurately detecting or recognizing objects. Therefore, people have proposed ways to simulate atmospheric turbulence and designed effective deep learning-based methods to remove the atmospheric turbulence effect. However, these synthesized turbulent images can not cover all the range of real-world turbulence effects. Though the models have achieved great performance for synthetic scenarios, there always exists a performance drop when applied to real-world cases. Moreover, reducing real-world turbulence is a more challenging task as there are no clean ground truth counterparts provided to the models during training. In this paper, we propose a real-world atmospheric turbulence mitigation model under a domain adaptation framework, which links the supervised simulated atmospheric turbulence correction with the unsupervised real-world atmospheric turbulence correction. We will show our proposed method enhances performance in real-world atmospheric turbulence scenarios, improving both image quality and downstream vision tasks.

Jiaqi Guo, Yunan Wu, Evangelos Kaimakamis et al.

With the advent of the COVID-19 pandemic, ultrasound imaging has emerged as a promising technique for COVID-19 detection, due to its non-invasive nature, affordability, and portability. In response, researchers have focused on developing AI-based scoring systems to provide real-time diagnostic support. However, the limited size and lack of proper annotation in publicly available ultrasound datasets pose significant challenges for training a robust AI model. This paper proposes MeDiVLAD, a novel pipeline to address the above issue for multi-level lung-ultrasound (LUS) severity scoring. In particular, we leverage self-knowledge distillation to pretrain a vision transformer (ViT) without label and aggregate frame-level features via dual-level VLAD aggregation. We show that with minimal finetuning, MeDiVLAD outperforms conventional fully-supervised methods in both frame- and video-level scoring, while offering classification reasoning with exceptional quality. This superior performance enables key applications such as the automatic identification of critical lung pathology areas and provides a robust solution for broader medical video classification tasks.

Hui Lin, Jiyang Li, Ramy Hussein et al.

Hypertension is a leading risk factor for cardiovascular diseases. Traditional blood pressure monitoring methods are cumbersome and inadequate for continuous tracking, prompting the development of PPG-based cuffless blood pressure monitoring wearables. This study leverages deep learning models, including ResNet and Transformer, to analyze wrist PPG data collected with a smartwatch for efficient hypertension risk screening, eliminating the need for handcrafted PPG features. Using the Home Blood Pressure Monitoring (HBPM) longitudinal dataset of 448 subjects and five-fold cross-validation, our model was trained on over 68k spot-check instances from 358 subjects and tested on real-world continuous recordings of 90 subjects. The compact ResNet model with 0.124M parameters performed significantly better than traditional machine learning methods, demonstrating its effectiveness in distinguishing between healthy and abnormal cases in real-world scenarios.

Francisco M. Castro-Macías, Pablo Morales-Álvarez, Yunan Wu et al.

The Multiple Instance Learning (MIL) paradigm is attracting plenty of attention in medical imaging classification, where labeled data is scarce. MIL methods cast medical images as bags of instances (e.g. patches in whole slide images, or slices in CT scans), and only bag labels are required for training. Deep MIL approaches have obtained promising results by aggregating instance-level representations via an attention mechanism to compute the bag-level prediction. These methods typically capture both local interactions among adjacent instances and global, long-range dependencies through various mechanisms. However, they treat attention values deterministically, potentially overlooking uncertainty in the contribution of individual instances. In this work we propose a novel probabilistic framework that estimates a probability distribution over the attention values, and accounts for both global and local interactions. In a comprehensive evaluation involving {\color{review} eleven} state-of-the-art baselines and three medical datasets, we show that our approach achieves top predictive performance in different metrics. Moreover, the probabilistic treatment of the attention provides uncertainty maps that are interpretable in terms of illness localization.

Jiaqi Guo, Santiago Lopez-Tapia, Aggelos K. Katsaggelos

Limited Angle Computed Tomography (LACT) often faces significant challenges due to missing angular information. Unlike previous methods that operate in the image domain, we propose a new method that focuses on sinogram inpainting. We leverage MR-SDEs, a variant of diffusion models that characterize the diffusion process with mean-reverting stochastic differential equations, to fill in missing angular data at the projection level. Furthermore, by combining distillation with constraining the output of the model using the pseudo-inverse of the inpainting matrix, the diffusion process is accelerated and done in a step, enabling efficient and accurate sinogram completion. A subsequent post-processing module back-projects the inpainted sinogram into the image domain and further refines the reconstruction, effectively suppressing artifacts while preserving critical structural details. Quantitative experimental results demonstrate that the proposed method achieves state-of-the-art performance in both perceptual and fidelity quality, offering a promising solution for LACT reconstruction in scientific and clinical applications.

Neda Tavakoli, Amir Ali Rahsepar, Brandon C. Benefield et al.

Background: Late Gadolinium Enhancement (LGE) imaging is the gold standard for assessing myocardial fibrosis and scarring, with left ventricular (LV) LGE extent predicting major adverse cardiac events (MACE). Despite its importance, routine LGE-based LV scar quantification is hindered by labor-intensive manual segmentation and inter-observer variability. Methods: We propose ScarNet, a hybrid model combining a transformer-based encoder from the Medical Segment Anything Model (MedSAM) with a convolution-based U-Net decoder, enhanced by tailored attention blocks. ScarNet was trained on 552 ischemic cardiomyopathy patients with expert segmentations of myocardial and scar boundaries and tested on 184 separate patients. Results: ScarNet achieved robust scar segmentation in 184 test patients, yielding a median Dice score of 0.912 (IQR: 0.863--0.944), significantly outperforming MedSAM (median Dice = 0.046, IQR: 0.043--0.047) and nnU-Net (median Dice = 0.638, IQR: 0.604--0.661). ScarNet demonstrated lower bias (-0.63%) and coefficient of variation (4.3%) compared to MedSAM (bias: -13.31%, CoV: 130.3%) and nnU-Net (bias: -2.46%, CoV: 20.3%). In Monte Carlo simulations with noise perturbations, ScarNet achieved significantly higher scar Dice (0.892 \pm 0.053, CoV = 5.9%) than MedSAM (0.048 \pm 0.112, CoV = 233.3%) and nnU-Net (0.615 \pm 0.537, CoV = 28.7%). Conclusion: ScarNet outperformed MedSAM and nnU-Net in accurately segmenting myocardial and scar boundaries in LGE images. The model exhibited robust performance across diverse image qualities and scar patterns.

Xijun Wang, Santiago López-Tapia, Alice Lucas et al.

Generative Adversarial Networks (GANs) have shown great performance on super-resolution problems since they can generate more visually realistic images and video frames. However, these models often introduce side effects into the outputs, such as unexpected artifacts and noises. To reduce these artifacts and enhance the perceptual quality of the results, in this paper, we propose a general method that can be effectively used in most GAN-based super-resolution (SR) models by introducing essential spatial information into the training process. We extract spatial information from the input data and incorporate it into the training loss, making the corresponding loss a spatially adaptive (SA) one. After that, we utilize it to guide the training process. We will show that the proposed approach is independent of the methods used to extract the spatial information and independent of the SR tasks and models. This method consistently guides the training process towards generating visually pleasing SR images and video frames, substantially mitigating artifacts and noise, ultimately leading to enhanced perceptual quality.

Xijun Wang, Santiago López-Tapia, Aggelos K. Katsaggelos

Atmospheric Turbulence (AT) correction is a challenging restoration task as it consists of two distortions: geometric distortion and spatially variant blur. Diffusion models have shown impressive accomplishments in photo-realistic image synthesis and beyond. In this paper, we propose a novel deep conditional diffusion model under a variational inference framework to solve the AT correction problem. We use this framework to improve performance by learning latent prior information from the input and degradation processes. We use the learned information to further condition the diffusion model. Experiments are conducted in a comprehensive synthetic AT dataset. We show that the proposed framework achieves good quantitative and qualitative results.

Xijun Wang, Aggelos K. Katsaggelos

Weakly-supervised temporal action localization aims to identify and localize the action instances in the untrimmed videos with only video-level action labels. When humans watch videos, we can adapt our abstract-level knowledge about actions in different video scenarios and detect whether some actions are occurring. In this paper, we mimic how humans do and bring a new perspective for locating and identifying multiple actions in a video. We propose a network named VQK-Net with a video-specific query-key attention modeling that learns a unique query for each action category of each input video. The learned queries not only contain the actions' knowledge features at the abstract level but also have the ability to fit this knowledge into the target video scenario, and they will be used to detect the presence of the corresponding action along the temporal dimension. To better learn these action category queries, we exploit not only the features of the current input video but also the correlation between different videos through a novel video-specific action category query learner worked with a query similarity loss. Finally, we conduct extensive experiments on three commonly used datasets (THUMOS14, ActivityNet1.2, and ActivityNet1.3) and achieve state-of-the-art performance.

Kyle Akira Rocha, Jeff J. Andrews, Christopher P. L. Berry et al.

Binary stars undergo a variety of interactions and evolutionary phases, critical for predicting and explaining observed properties. Binary population synthesis with full stellar-structure and evolution simulations are computationally expensive requiring a large number of mass-transfer sequences. The recently developed binary population synthesis code POSYDON incorporates grids of MESA binary star simulations which are then interpolated to model large-scale populations of massive binaries. The traditional method of computing a high-density rectilinear grid of simulations is not scalable for higher-dimension grids, accounting for a range of metallicities, rotation, and eccentricity. We present a new active learning algorithm, psy-cris, which uses machine learning in the data-gathering process to adaptively and iteratively select targeted simulations to run, resulting in a custom, high-performance training set. We test psy-cris on a toy problem and find the resulting training sets require fewer simulations for accurate classification and regression than either regular or randomly sampled grids. We further apply psy-cris to the target problem of building a dynamic grid of MESA simulations, and we demonstrate that, even without fine tuning, a simulation set of only $\sim 1/4$ the size of a rectilinear grid is sufficient to achieve the same classification accuracy. We anticipate further gains when algorithmic parameters are optimized for the targeted application. We find that optimizing for classification only may lead to performance losses in regression, and vice versa. Lowering the computational cost of producing grids will enable future versions of POSYDON to cover more input parameters while preserving interpolation accuracies.

Amil Dravid, Florian Schiffers, Yunan Wu et al.

Generative Adversarial Networks (GANs) have shown promise in augmenting datasets and boosting convolutional neural networks' (CNN) performance on image classification tasks. But they introduce more hyperparameters to tune as well as the need for additional time and computational power to train supplementary to the CNN. In this work, we examine the potential for Auxiliary-Classifier GANs (AC-GANs) as a 'one-stop-shop' architecture for image classification, particularly in low data regimes. Additionally, we explore modifications to the typical AC-GAN framework, changing the generator's latent space sampling scheme and employing a Wasserstein loss with gradient penalty to stabilize the simultaneous training of image synthesis and classification. Through experiments on images of varying resolutions and complexity, we demonstrate that AC-GANs show promise in image classification, achieving competitive performance with standard CNNs. These methods can be employed as an 'all-in-one' framework with particular utility in the absence of large amounts of training data.

Amil Dravid, Aggelos K. Katsaggelos

Lack of explainability in artificial intelligence, specifically deep neural networks, remains a bottleneck for implementing models in practice. Popular techniques such as Gradient-weighted Class Activation Mapping (Grad-CAM) provide a coarse map of salient features in an image, which rarely tells the whole story of what a convolutional neural network (CNN) learned. Using COVID-19 chest X-rays, we present a method for interpreting what a CNN has learned by utilizing Generative Adversarial Networks (GANs). Our GAN framework disentangles lung structure from COVID-19 features. Using this GAN, we can visualize the transition of a pair of COVID negative lungs in a chest radiograph to a COVID positive pair by interpolating in the latent space of the GAN, which provides fine-grained visualization of how the CNN responds to varying features within the lungs.

Henry H. Chopp, Srutarshi Banerjee, Oliver Cossairt et al.

In this paper, we propose EveRestNet, a convolutional neural network designed to remove blocking artifacts in videostreams using events from neuromorphic sensors. We first degrade the video frame using a quadtree structure to produce the blocking artifacts to simulate transmitting a video under a heavily constrained bandwidth. Events from the neuromorphic sensor are also simulated, but are transmitted in full. Using the distorted frames and the event stream, EveRestNet is able to improve the image quality.

Xin Yuan, David J. Brady, Aggelos K. Katsaggelos

Capturing high-dimensional (HD) data is a long-term challenge in signal processing and related fields. Snapshot compressive imaging (SCI) uses a two-dimensional (2D) detector to capture HD ($\ge3$D) data in a {\em snapshot} measurement. Via novel optical designs, the 2D detector samples the HD data in a {\em compressive} manner; following this, algorithms are employed to reconstruct the desired HD data-cube. SCI has been used in hyperspectral imaging, video, holography, tomography, focal depth imaging, polarization imaging, microscopy, \etc.~Though the hardware has been investigated for more than a decade, the theoretical guarantees have only recently been derived. Inspired by deep learning, various deep neural networks have also been developed to reconstruct the HD data-cube in spectral SCI and video SCI. This article reviews recent advances in SCI hardware, theory and algorithms, including both optimization-based and deep-learning-based algorithms. Diverse applications and the outlook of SCI are also discussed.

Merlin A. Nau, Florian Schiffers, Yunhao Li et al.

The utilization of computational photography becomes increasingly essential in the medical field. Today, imaging techniques for dermatology range from two-dimensional (2D) color imagery with a mobile device to professional clinical imaging systems measuring additional detailed three-dimensional (3D) data. The latter are commonly expensive and not accessible to a broad audience. In this work, we propose a novel system and software framework that relies only on low-cost (and even mobile) commodity devices present in every household to measure detailed 3D information of the human skin with a 3D-gradient-illumination-based method. We believe that our system has great potential for early-stage diagnosis and monitoring of skin diseases, especially in vastly populated or underdeveloped areas.

Alexis Baudron, Zihao W. Wang, Oliver Cossairt et al.

3D shape reconstruction is a primary component of augmented/virtual reality. Despite being highly advanced, existing solutions based on RGB, RGB-D and Lidar sensors are power and data intensive, which introduces challenges for deployment in edge devices. We approach 3D reconstruction with an event camera, a sensor with significantly lower power, latency and data expense while enabling high dynamic range. While previous event-based 3D reconstruction methods are primarily based on stereo vision, we cast the problem as multi-view shape from silhouette using a monocular event camera. The output from a moving event camera is a sparse point set of space-time gradients, largely sketching scene/object edges and contours. We first introduce an event-to-silhouette (E2S) neural network module to transform a stack of event frames to the corresponding silhouettes, with additional neural branches for camera pose regression. Second, we introduce E3D, which employs a 3D differentiable renderer (PyTorch3D) to enforce cross-view 3D mesh consistency and fine-tune the E2S and pose network. Lastly, we introduce a 3D-to-events simulation pipeline and apply it to publicly available object datasets and generate synthetic event/silhouette training pairs for supervised learning.

Haoyu Wei, Florian Schiffers, Tobias Würfl et al.

Computed tomography is widely used to examine internal structures in a non-destructive manner. To obtain high-quality reconstructions, one typically has to acquire a densely sampled trajectory to avoid angular undersampling. However, many scenarios require a sparse-view measurement leading to streak-artifacts if unaccounted for. Current methods do not make full use of the domain-specific information, and hence fail to provide reliable reconstructions for highly undersampled data. We present a novel framework for sparse-view tomography by decoupling the reconstruction into two steps: First, we overcome its ill-posedness using a super-resolution network, SIN, trained on the sparse projections. The intermediate result allows for a closed-form tomographic reconstruction with preserved details and highly reduced streak-artifacts. Second, a refinement network, PRN, trained on the reconstructions reduces any remaining artifacts. We further propose a light-weight variant of the perceptual-loss that enhances domain-specific information, boosting restoration accuracy. Our experiments demonstrate an improvement over current solutions by 4 dB.

Emanuel A. Azcona, Pierre Besson, Yunan Wu et al.

We propose a mesh-based technique to aid in the classification of Alzheimer's disease dementia (ADD) using mesh representations of the cortex and subcortical structures. Deep learning methods for classification tasks that utilize structural neuroimaging often require extensive learning parameters to optimize. Frequently, these approaches for automated medical diagnosis also lack visual interpretability for areas in the brain involved in making a diagnosis. This work: (a) analyzes brain shape using surface information of the cortex and subcortical structures, (b) proposes a residual learning framework for state-of-the-art graph convolutional networks which offer a significant reduction in learnable parameters, and (c) offers visual interpretability of the network via class-specific gradient information that localizes important regions of interest in our inputs. With our proposed method leveraging the use of cortical and subcortical surface information, we outperform other machine learning methods with a 96.35% testing accuracy for the ADD vs. healthy control problem. We confirm the validity of our model by observing its performance in a 25-trial Monte Carlo cross-validation. The generated visualization maps in our study show correspondences with current knowledge regarding the structural localization of pathological changes in the brain associated to dementia of the Alzheimer's type.

Arjun Punjabi, Jonas Schmid, Aggelos K. Katsaggelos

Capsule networks are a recently developed class of neural networks that potentially address some of the deficiencies with traditional convolutional neural networks. By replacing the standard scalar activations with vectors, and by connecting the artificial neurons in a new way, capsule networks aim to be the next great development for computer vision applications. However, in order to determine whether these networks truly operate differently than traditional networks, one must look at the differences in the capsule features. To this end, we perform several analyses with the purpose of elucidating capsule features and determining whether they perform as described in the initial publication. First, we perform a deep visualization analysis to visually compare capsule features and convolutional neural network features. Then, we look at the ability for capsule features to encode information across the vector components and address what changes in the capsule architecture provides the most benefit. Finally, we look at how well the capsule features are able to encode instantiation parameters of class objects via visual transformations.

Alice Lucas, Santiago Lopez-Tapia, Rafael Molina et al.

While Convolutional Neural Networks (CNNs) trained for image and video super-resolution (SR) regularly achieve new state-of-the-art performance, they also suffer from significant drawbacks. One of their limitations is their lack of robustness to unseen image formation models during training. Other limitations include the generation of artifacts and hallucinated content when training Generative Adversarial Networks (GANs) for SR. While the Deep Learning literature focuses on presenting new training schemes and settings to resolve these various issues, we show that one can avoid training and correct for SR results with a fully self-supervised fine-tuning approach. More specifically, at test time, given an image and its known image formation model, we fine-tune the parameters of the trained network and iteratively update them using a data fidelity loss. We apply our fine-tuning algorithm on multiple image and video SR CNNs and show that it can successfully correct for a sub-optimal SR solution by entirely relying on internal learning at test time. We apply our method on the problem of fine-tuning for unseen image formation models and on removal of artifacts introduced by GANs.

Pablo Morales-Álvarez, Pablo Ruiz, Scott Coughlin et al.

In the last years, crowdsourcing is transforming the way classification training sets are obtained. Instead of relying on a single expert annotator, crowdsourcing shares the labelling effort among a large number of collaborators. For instance, this is being applied to the data acquired by the laureate Laser Interferometer Gravitational Waves Observatory (LIGO), in order to detect glitches which might hinder the identification of true gravitational-waves. The crowdsourcing scenario poses new challenging difficulties, as it deals with different opinions from a heterogeneous group of annotators with unknown degrees of expertise. Probabilistic methods, such as Gaussian Processes (GP), have proven successful in modeling this setting. However, GPs do not scale well to large data sets, which hampers their broad adoption in real practice (in particular at LIGO). This has led to the recent introduction of deep learning based crowdsourcing methods, which have become the state-of-the-art. However, the accurate uncertainty quantification of GPs has been partially sacrificed. This is an important aspect for astrophysicists in LIGO, since a glitch detection system should provide very accurate probability distributions of its predictions. In this work, we leverage the most popular sparse GP approximation to develop a novel GP based crowdsourcing method that factorizes into mini-batches. This makes it able to cope with previously-prohibitive data sets. The approach, which we refer to as Scalable Variational Gaussian Processes for Crowdsourcing (SVGPCR), brings back GP-based methods to the state-of-the-art, and excels at uncertainty quantification. SVGPCR is shown to outperform deep learning based methods and previous probabilistic approaches when applied to the LIGO data. Moreover, its behavior and main properties are carefully analyzed in a controlled experiment based on the MNIST data set.

Ali Bahrami Rad, Morteza Zabihi, Zheng Zhao et al.

Objective: The aim of this study is to develop an automated classification algorithm for polysomnography (PSG) recordings to detect non-apneic and non-hypopneic arousals. Our particular focus is on detecting the respiratory effort-related arousals (RERAs) which are very subtle respiratory events that do not meet the criteria for apnea or hypopnea, and are more challenging to detect. Methods: The proposed algorithm is based on a bidirectional long short-term memory (BiLSTM) classifier and 465 multi-domain features, extracted from multimodal clinical time series. The features consist of a set of physiology-inspired features (n = 75), obtained by multiple steps of feature selection and expert analysis, and a set of physiology-agnostic features (n = 390), derived from scattering transform. Results: The proposed algorithm is validated on the 2018 PhysioNet challenge dataset. The overall performance in terms of the area under the precision-recall curve (AUPRC) is 0.50 on the hidden test dataset. This result is tied for the second-best score during the follow-up and official phases of the 2018 PhysioNet challenge. Conclusions: The results demonstrate that it is possible to automatically detect subtle non-apneic/non-hypopneic arousal events from PSG recordings. Significance: Automatic detection of subtle respiratory events such as RERAs together with other non-apneic/non-hypopneic arousals will allow detailed annotations of large PSG databases. This contributes to a better retrospective analysis of sleep data, which may also improve the quality of treatment.

Santiago López-Tapia, Alice Lucas, Rafael Molina et al.

The popularity of high and ultra-high definition displays has led to the need for methods to improve the quality of videos already obtained at much lower resolutions. Current Video Super-Resolution methods are not robust to mismatch between training and testing degradation models since they are trained against a single degradation model (usually bicubic downsampling). This causes their performance to deteriorate in real-life applications. At the same time, the use of only the Mean Squared Error during learning causes the resulting images to be too smooth. In this work we propose a new Convolutional Neural Network for video super resolution which is robust to multiple degradation models. During training, which is performed on a large dataset of scenes with slow and fast motions, it uses the pseudo-inverse image formation model as part of the network architecture in conjunction with perceptual losses, in addition to a smoothness constraint that eliminates the artifacts originating from these perceptual losses. The experimental validation shows that our approach outperforms current state-of-the-art methods and is robust to multiple degradations.

Qiqin Dai, Henry Chopp, Emeline Pouyet et al.

This paper presents an adaptive image sampling algorithm based on Deep Learning (DL). The adaptive sampling mask generation network is jointly trained with an image inpainting network. The sampling rate is controlled in the mask generation network, and a binarization strategy is investigated to make the sampling mask binary. Besides the image sampling and reconstruction application, we show that the proposed adaptive sampling algorithm is able to speed up raster scan processes such as the X-Ray fluorescence (XRF) image scanning process. Recently XRF laboratory-based systems have evolved to lightweight and portable instruments thanks to technological advancements in both X-Ray generation and detection. However, the scanning time of an XRF image is usually long due to the long exposures requires (e.g., $100 μs-1ms$ per point). We propose an XRF image inpainting approach to address the issue of long scanning time, thus speeding up the scanning process while still maintaining the possibility to reconstruct a high quality XRF image. The proposed adaptive image sampling algorithm is applied to the RGB image of the scanning target to generate the sampling mask. The XRF scanner is then driven according to the sampling mask to scan a subset of the total image pixels. Finally, we inpaint the scanned XRF image by fusing the RGB image to reconstruct the full scan XRF image. The experiments show that the proposed adaptive sampling algorithm is able to effectively sample the image and achieve a better reconstruction accuracy than that of the existing methods.

Arjun Punjabi, Adam Martersteck, Yanran Wang et al.

Automated methods for Alzheimer's disease (AD) classification have the potential for great clinical benefits and may provide insight for combating the disease. Machine learning, and more specifically deep neural networks, have been shown to have great efficacy in this domain. These algorithms often use neurological imaging data such as MRI and PET, but a comprehensive and balanced comparison of these modalities has not been performed. In order to accurately determine the relative strength of each imaging variant, this work performs a comparison study in the context of Alzheimer's dementia classification using the Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset. Furthermore, this work analyzes the benefits of using both modalities in a fusion setting and discusses how these data types may be leveraged in future AD studies using deep learning.

Alice Lucas, Santiago Lopez Tapia, Rafael Molina et al.

Video super-resolution (VSR) has become one of the most critical problems in video processing. In the deep learning literature, recent works have shown the benefits of using adversarial-based and perceptual losses to improve the performance on various image restoration tasks; however, these have yet to be applied for video super-resolution. In this work, we propose a Generative Adversarial Network(GAN)-based formulation for VSR. We introduce a new generator network optimized for the VSR problem, named VSRResNet, along with a new discriminator architecture to properly guide VSRResNet during the GAN training. We further enhance our VSR GAN formulation with two regularizers, a distance loss in feature-space and pixel-space, to obtain our final VSRResFeatGAN model. We show that pre-training our generator with the Mean-Squared-Error loss only quantitatively surpasses the current state-of-the-art VSR models. Finally, we employ the PercepDist metric (Zhang et al., 2018) to compare state-of-the-art VSR models. We show that this metric more accurately evaluates the perceptual quality of SR solutions obtained from neural networks, compared with the commonly used PSNR/SSIM metrics. Finally, we show that our proposed model, the VSRResFeatGAN model, outperforms current state-of-the-art SR models, both quantitatively and qualitatively.

Sara Bahaadini, Vahid Noroozi, Neda Rohani et al.

In this paper, benefiting from the strong ability of deep neural network in estimating non-linear functions, we propose a discriminative embedding function to be used as a feature extractor for clustering tasks. The trained embedding function transfers knowledge from the domain of a labeled set of morphologically-distinct images, known as classes, to a new domain within which new classes can potentially be isolated and identified. Our target application in this paper is the Gravity Spy Project, which is an effort to characterize transient, non-Gaussian noise present in data from the Advanced Laser Interferometer Gravitational-wave Observatory, or LIGO. Accumulating large, labeled sets of noise features and identifying of new classes of noise lead to a better understanding of their origin, which makes their removal from the data and/or detectors possible.

Linjie Yang, Yanran Wang, Xuehan Xiong et al.

Video object segmentation targets at segmenting a specific object throughout a video sequence, given only an annotated first frame. Recent deep learning based approaches find it effective by fine-tuning a general-purpose segmentation model on the annotated frame using hundreds of iterations of gradient descent. Despite the high accuracy these methods achieve, the fine-tuning process is inefficient and fail to meet the requirements of real world applications. We propose a novel approach that uses a single forward pass to adapt the segmentation model to the appearance of a specific object. Specifically, a second meta neural network named modulator is learned to manipulate the intermediate layers of the segmentation network given limited visual and spatial information of the target object. The experiments show that our approach is 70times faster than fine-tuning approaches while achieving similar accuracy.

Zihao Wang, Leonidas Spinoulas, Kuan He et al.

Compressed sensing has been discussed separately in spatial and temporal domains. Compressive holography has been introduced as a method that allows 3D tomographic reconstruction at different depths from a single 2D image. Coded exposure is a temporal compressed sensing method for high speed video acquisition. In this work, we combine compressive holography and coded exposure techniques and extend the discussion to 4D reconstruction in space and time from one coded captured image. In our prototype, digital in-line holography was used for imaging macroscopic, fast moving objects. The pixel-wise temporal modulation was implemented by a digital micromirror device. In this paper we demonstrate $10\times$ temporal super resolution with multiple depths recovery from a single image. Two examples are presented for the purpose of recording subtle vibrations and tracking small particles within 5 ms.