Zhonghao Liu

Zhonghao Liu, Yahao Ding, Yinchao Yang et al.

Integrated sensing, communication, and computation (ISCC) provides a promising framework for indoor human-centric applications. In these applications, short-term human pose prediction facilitates continuous human tracking and resource allocation in advance. In this paper, we propose a Cramer-Rao bound (CRB) guided resource allocation framework for indoor mmWave ISCC systems to minimize the human pose prediction error under communication, latency, and energy constraints. We characterize the impact of sensing power on range-estimation uncertainty and point-cloud perturbation based on the CRB. To capture the impact of computation resources on prediction performance, we adopt an adaptive-depth Mamba-based pose prediction model, where lightweight prediction heads are attached after every layer to enable inference with different model depths. With this unified sensing-computation modeling, we establish a quantitative relationship among sensing power, model depth, and prediction error. Furthermore, we formulate a joint resource allocation problem to minimize the pose prediction error. To solve this problem efficiently, we develop an alternating optimization (AO)-based algorithm, where closed-form solutions are derived for the sensing power and model depth update steps. Simulation results show that the proposed scheme significantly reduces pose prediction error compared with baseline methods, validating its effectiveness for resource-constrained indoor human-centric ISCC systems.

Zhonghao Liu, Yinchao Yang, Yahao Ding et al.

This paper investigates a multi-user indoor integrated sensing and communication (ISAC) system operating in the terahertz (THz) band, designed for adaptive communication based on gesture recognition. Leveraging gesture tracking through an extended Kalman filter (EKF), the access point (AP) dynamically adjusts resource allocation in response to detected gesture variations, thereby improving sensing accuracy. Based on the gesture recognition results, the AP further updates the communication quality requirements of different users, enabling efficient resource allocation. To this end, an adaptive joint optimization algorithm for power allocation and beamforming is developed to maximize the overall sensing signal-to-interference-plus-noise ratio (SINR) while satisfying the gesture-dependent communication quality of service (QoS) constraints. Simulation results demonstrate that the proposed method effectively responds to gesture dynamics, achieving superior sensing accuracy and communication performance compared with conventional single-variable optimization baselines.

Zhonghao Liu, Hanxue Gu, Qihang Li et al.

Reliable measurement of glenoid bone loss is essential for operative planning in shoulder instability, but current manual and semi-automated methods are time-consuming and often subject to interreader variability. We developed and validated a fully automated deep learning pipeline for measuring glenoid bone loss on three-dimensional computed tomography (CT) scans using a linear-based, en-face view, best-circle method. Shoulder CT images of 91 patients (average age, 40 years; range, 14-89 years; 65 men) were retrospectively collected along with manual labels including glenoid segmentation, landmarks, and bone loss measurements. The multi-stage algorithm has three main stages: (1) segmentation, where we developed a U-Net to automatically segment the glenoid and humerus; (2) anatomical landmark detection, where a second network predicts glenoid rim points; and (3) geometric fitting, where we applied principal component analysis (PCA), projection, and circle fitting to compute the percentage of bone loss. The automated measurements showed strong agreement with consensus readings and exceeded surgeon-to-surgeon consistency (intraclass correlation coefficient (ICC) 0.84 vs 0.78), including in low- and high-bone-loss subgroups (ICC 0.71 vs 0.63 and 0.83 vs 0.21, respectively; P < 0.001). For classifying patients into low, medium, and high bone-loss categories, the pipeline achieved a recall of 0.714 for low and 0.857 for high severity, with no low cases misclassified as high or vice versa. These results suggest that our method is a time-efficient and clinically reliable tool for preoperative planning in shoulder instability and for screening patients with substantial glenoid bone loss. Code and dataset are available at https://github.com/Edenliu1/Auto-Glenoid-Measurement-DL-Pipeline.

Roy Colglazier, Jisoo Lee, Haoyu Dong et al.

The quantity and quality of muscles are increasingly recognized as important predictors of health outcomes. While MRI offers a valuable modality for such assessments, obtaining precise quantitative measurements of musculature remains challenging. This study aimed to develop a publicly available model for muscle segmentation in MRIs and demonstrate its applicability across various anatomical locations and imaging sequences. A total of 362 MRIs from 160 patients at a single tertiary center (Duke University Health System, 2016-2020) were included, with 316 MRIs from 114 patients used for model development. The model was tested on two separate sets: one with 28 MRIs representing common sequence types, achieving an average Dice Similarity Coefficient (DSC) of 88.45%, and another with 18 MRIs featuring less frequent sequences and abnormalities such as muscular atrophy, hardware, and significant noise, achieving 86.21% DSC. These results demonstrate the feasibility of a fully automated deep learning algorithm for segmenting muscles on MRI across diverse settings. The public release of this model enables consistent, reproducible research into the relationship between musculature and health.

Yuxin Cui, Guiying Zhang, Zhonghao Liu et al.

This paper addresses the task of nuclei segmentation in high-resolution histopathological images. We propose an auto- matic end-to-end deep neural network algorithm for segmenta- tion of individual nuclei. A nucleus-boundary model is introduced to predict nuclei and their boundaries simultaneously using a fully convolutional neural network. Given a color normalized image, the model directly outputs an estimated nuclei map and a boundary map. A simple, fast and parameter-free post-processing procedure is performed on the estimated nuclei map to produce the final segmented nuclei. An overlapped patch extraction and assembling method is also designed for seamless prediction of nuclei in large whole-slide images. We also show the effectiveness of data augmentation methods for nuclei segmentation task. Our experiments showed our method outperforms prior state-of-the- art methods. Moreover, it is efficient that one 1000X1000 image can be segmented in less than 5 seconds. This makes it possible to precisely segment the whole-slide image in acceptable time