Raymond Xiong

Raymond Xiong, Furong Jia, Lionel Wong et al.

Patients are increasingly using large language models (LLMs) to seek answers to their healthcare-related questions. However, benchmarking efforts in LLMs for question answering often focus on medical exam questions, which differ significantly in style and content from the questions patients actually raise in real life. To bridge this gap, we sourced data from Google's People Also Ask feature by querying the top 200 prescribed medications in the United States, curating a dataset of medical questions people commonly ask. A considerable portion of the collected questions contains incorrect assumptions and dangerous intentions. We demonstrate that the emergence of these corrupted questions is not uniformly random and depends heavily on the degree of incorrectness in the history of questions that led to their appearance. Current LLMs that perform strongly on other benchmarks struggle to identify incorrect assumptions in everyday questions.

Lionel Wong, Ayman Ali, Raymond Xiong et al. · mit

Patients have long sought health information online, and increasingly, they are turning to generative AI to answer their health-related queries. Given the high stakes of the medical domain, techniques like retrieval-augmented generation and citation grounding have been widely promoted as methods to reduce hallucinations and improve the accuracy of AI-generated responses and have been widely adopted into search engines. This paper argues that even when these methods produce literally accurate content drawn from source documents sans hallucinations, they can still be highly misleading. Patients may derive significantly different interpretations from AI-generated outputs than they would from reading the original source material, let alone consulting a knowledgeable clinician. Through a large-scale query analysis on topics including disputed diagnoses and procedure safety, we support our argument with quantitative and qualitative evidence of the suboptimal answers resulting from current systems. In particular, we highlight how these models tend to decontextualize facts, omit critical relevant sources, and reinforce patient misconceptions or biases. We propose a series of recommendations -- such as the incorporation of communication pragmatics and enhanced comprehension of source documents -- that could help mitigate these issues and extend beyond the medical domain.