Jianwen Luo

Shangqing Tong, Hengrong Lan, Liming Nie et al.

Photoacoustic tomography (PAT) is a newly emerged imaging modality which enables both high optical contrast and acoustic depth of penetration. Reconstructing images of photoacoustic tomography from limited amount of senser data is among one of the major challenges in photoacoustic imaging. Previous works based on deep learning were trained in supervised fashion, which directly map the input partially known sensor data to the ground truth reconstructed from full field of view. Recently, score-based generative models played an increasingly significant role in generative modeling. Leveraging this probabilistic model, we proposed Rotation Consistency Constrained Score-based Generative Model (RCC-SGM), which recovers the PAT images by iterative sampling between Langevin dynamics and a constraint term utilizing the rotation consistency between the images and the measurements. Our proposed method can generalize to different measurement processes (32.29 PSNR with 16 measurements under random sampling, whereas 28.50 for supervised counterpart), while supervised methods need to train on specific inverse mappings.

Hengrong Lan, Zhiqiang Li, Qiong He et al.

Image reconstruction from radio-frequency data is pivotal in ultrafast plane wave ultrasound imaging. Unlike the conventional delay-and-sum (DAS) technique, which relies on somewhat imprecise assumptions, deep learning-based methods perform image reconstruction by training on paired data, leading to a notable enhancement in image quality. Nevertheless, these strategies often exhibit limited generalization capabilities. Recently, denoising diffusion models have become the preferred paradigm for image reconstruction tasks. However, their reliance on an iterative sampling procedure results in prolonged generation time. In this paper, we propose a novel sampling framework that concurrently enforces data consistency of ultrasound signals and data-driven priors. By leveraging the advanced diffusion model, the generation of high-quality images is substantially expedited. Experimental evaluations on an in-vivo dataset indicate that our approach with a single plane wave surpasses DAS with spatial coherent compounding of 75 plane waves.

Zhiqiang Li, Hengrong Lan, Lijie Huang et al.

Reconstruction of ultrasound (US) images from radio-frequency data can be conceptualized as a linear inverse problem. Traditional deep learning approaches, which aim to improve the quality of US images by directly learning priors, often encounter challenges in generalization. Recently, diffusion-based generative models have received significant attention within the research community due to their robust performance in image reconstruction tasks. However, a limitation of these models is their inherent low speed in generating image samples from pure Gaussian noise progressively. In this study, we exploit the inherent similarity between the US images reconstructed from a single plane wave (PW) and PW compounding PWC). We hypothesize that a single PW can take a shortcut to reach the diffusion trajectory of PWC, removing the need to begin with Gaussian noise. By employing an advanced diffusion model, we demonstrate its effectiveness in US image reconstruction, achieving a substantial reduction in sampling steps. In-vivo experimental results indicate that our approach can reduce sampling steps by 60%, while preserving comparable performance metrics with the conventional diffusion model.

Yueheng Zhou, Ming Liu, Chaoyang Song et al.

The quadruped robot is a versatile mobile platform with potential ability for high payload carrying. However, most of the existing quadruped robots aim at high maneuverability, highly dynamic and agile locomotion. In spite of this, payload carrying is still an indispensable ability for the quadruped robots. Design of a quadruped robot with high payload capacity is yet deeply explored. In this study, a 50 kg electrically-actuated quadruped robot, Kirin, is presented to leverage the payload carrying capability. Kirin is an characterized with prismatic quasi-direct-drive (QDD) leg. This mechanism greatly augments the payload carrying capability. This study presents several design principles for the payload-carrying-oriented quadruped robots, including the mechanical design, actuator parameters selection, and locomotion control method. The theoretical analysis implies that the lifting task tends to be a bottleneck for the existing robots with the articulated knee joints. By using prismatic QDD leg, the payload carrying capability of Kirin is enhanced greatly. To demonstrate Kirin's payload carrying capability, in preliminary experiment, up to 125 kg payload lifting in static stance and 50 kg payload carrying in dynamic trotting are tested. Whole body compliance with payload carrying is also demonstrated.

Yuanyuan Wang, Yao Zhang, Qiong He et al.

This paper proposes a semi-automatic system based on quantitative characterization of the specific image patterns in lung ultrasound (LUS) images, in order to assess the lung conditions of patients with COVID-19 pneumonia, as well as to differentiate between the severe / and no-severe cases. Specifically, four parameters are extracted from each LUS image, namely the thickness (TPL) and roughness (RPL) of the pleural line, and the accumulated with (AWBL) and acoustic coefficient (ACBL) of B lines. 27 patients are enrolled in this study, which are grouped into 13 moderate patients, 7 severe patients and 7 critical patients. Furthermore, the severe and critical patients are regarded as the severe cases, and the moderate patients are regarded as the non-severe cases. Biomarkers among different groups are compared. Each single biomarker and a classifier with all the biomarkers as input are utilized for the binary diagnosis of severe case and non-severe case, respectively. The classifier achieves the best classification performance among all the compared methods (area under the receiver operating characteristics curve = 0.93, sensitivity = 0.93, specificity = 0.85). The proposed image analysis system could be potentially applied to the grading and prognosis evaluation of patients with COVID-19 pneumonia.

Jianwen Luo, Sicong Liu, Chengyu Lin et al.

Supernumerary Robotics Device (SRD) is an ideal solution to provide robotic assistance in overhead manual manipulation. Since two arms are occupied for the overhead task, it is desired to have additional arms to assist us in achieving other subtasks such as supporting the far end of a long plate and pushing it upward to fit in the ceiling. In this study, a method that maps human muscle force to SRD for overhead task assistance is proposed. Our methodology is to utilize redundant DoFs such as the idle muscles in the leg to control the supporting force of the SRD. A sEMG device is worn on the operator's shank where muscle signals are measured, parsed, and transmitted to SRD for control. In the control aspect, we adopted stiffness control in the task space based on torque control at the joint level. We are motivated by the fact that humans can achieve daily manipulation merely through simple inherent compliance property in joint driven by muscles. We explore to estimate the force of some particular muscles in humans and control the SRD to imitate the behaviors of muscle and output supporting forces to accomplish the subtasks such as overhead supporting. The sEMG signals detected from human muscles are extracted, filtered, rectified, and parsed to estimate the muscle force. We use this force information as the intent of the operator for proper overhead supporting force. As one of the well-known compliance control methods, stiffness control is easy to achieve using a few of straightforward parameters such as stiffness and equilibrium point. Through tuning the stiffness and equilibrium point, the supporting force of SRD in task space can be easily controlled. The muscle force estimated by sEMG is mapped to the desired force in the task space of the SRD. The desired force is transferred into stiffness or equilibrium point to output the corresponding supporting force.

Bingchen Jin, Yueheng Zhou, Ye Zhao et al.

Quadruped robots manifest great potential to traverse rough terrains with payload. Numerous traditional control methods for legged dynamic locomotion are model-based and exhibit high sensitivity to model uncertainties and payload variations. Therefore, high-performance model parameter estimation becomes indispensable. However, the inertia parameters of payload are usually unknown and dynamically changing when the quadruped robot is deployed in versatile tasks. To address this problem, online identification of the inertia parameters and the Center of Mass (CoM) position of the payload for the quadruped robots draw an increasing interest. This study presents an adaptive controller based on the online payload identification for the high payload capacity (the ratio between payload and robot's self-weight) quadruped locomotion. We name it as Adaptive Controller for Quadruped Locomotion (ACQL), which consists of a recursive update law and a control law. ACQL estimates the external forces and torques induced by the payload online. The estimation is incorporated in inverse-dynamics-based Quadratic Programming (QP) to realize a trotting gait. As such, the tracking accuracy of the robot's CoM and orientation trajectories are improved. The proposed method, ACQL, is verified in a real quadruped robot platform. Experiments prove the estimation efficacy for the payload weighing from 20 $kg$ to 75 $kg$ and loaded at different locations of the robot's torso.

Tri Vu, Anthony DiSpirito, Daiwei Li et al.

Photoacoustic microscopy (PAM) is an emerging imaging method combining light and sound. However, limited by the laser's repetition rate, state-of-the-art high-speed PAM technology often sacrifices spatial sampling density (i.e., undersampling) for increased imaging speed over a large field-of-view. Deep learning (DL) methods have recently been used to improve sparsely sampled PAM images; however, these methods often require time-consuming pre-training and large training dataset with ground truth. Here, we propose the use of deep image prior (DIP) to improve the image quality of undersampled PAM images. Unlike other DL approaches, DIP requires neither pre-training nor fully-sampled ground truth, enabling its flexible and fast implementation on various imaging targets. Our results have demonstrated substantial improvement in PAM images with as few as 1.4$\%$ of the fully sampled pixels on high-speed PAM. Our approach outperforms interpolation, is competitive with pre-trained supervised DL method, and is readily translated to other high-speed, undersampling imaging modalities.

Anthony DiSpirito, Daiwei Li, Tri Vu et al.

One primary technical challenge in photoacoustic microscopy (PAM) is the necessary compromise between spatial resolution and imaging speed. In this study, we propose a novel application of deep learning principles to reconstruct undersampled PAM images and transcend the trade-off between spatial resolution and imaging speed. We compared various convolutional neural network (CNN) architectures, and selected a fully dense U-net (FD U-net) model that produced the best results. To mimic various undersampling conditions in practice, we artificially downsampled fully-sampled PAM images of mouse brain vasculature at different ratios. This allowed us to not only definitively establish the ground truth, but also train and test our deep learning model at various imaging conditions. Our results and numerical analysis have collectively demonstrated the robust performance of our model to reconstruct PAM images with as few as 2% of the original pixels, which may effectively shorten the imaging time without substantially sacrificing the image quality.

Oren Solomon, Regev Cohen, Yi Zhang et al.

Contrast enhanced ultrasound is a radiation-free imaging modality which uses encapsulated gas microbubbles for improved visualization of the vascular bed deep within the tissue. It has recently been used to enable imaging with unprecedented subwavelength spatial resolution by relying on super-resolution techniques. A typical preprocessing step in super-resolution ultrasound is to separate the microbubble signal from the cluttering tissue signal. This step has a crucial impact on the final image quality. Here, we propose a new approach to clutter removal based on robust principle component analysis (PCA) and deep learning. We begin by modeling the acquired contrast enhanced ultrasound signal as a combination of a low rank and sparse components. This model is used in robust PCA and was previously suggested in the context of ultrasound Doppler processing and dynamic magnetic resonance imaging. We then illustrate that an iterative algorithm based on this model exhibits improved separation of microbubble signal from the tissue signal over commonly practiced methods. Next, we apply the concept of deep unfolding to suggest a deep network architecture tailored to our clutter filtering problem which exhibits improved convergence speed and accuracy with respect to its iterative counterpart. We compare the performance of the suggested deep network on both simulations and in-vivo rat brain scans, with a commonly practiced deep-network architecture and the fast iterative shrinkage algorithm, and show that our architecture exhibits better image quality and contrast.