Xiaoqing Liu

Chaoqi Chen, Jiongcheng Li, Xiaoguang Han et al.

Domain generalization (DG) aims to improve the generalization performance for an unseen target domain by using the knowledge of multiple seen source domains. Mainstream DG methods typically assume that the domain label of each source sample is known a priori, which is challenged to be satisfied in many real-world applications. In this paper, we study a practical problem of compound DG, which relaxes the discrete domain assumption to the mixed source domains setting. On the other hand, current DG algorithms prioritize the focus on semantic invariance across domains (one-vs-one), while paying less attention to the holistic semantic structure (many-vs-many). Such holistic semantic structure, referred to as meta-knowledge here, is crucial for learning generalizable representations. To this end, we present Compound Domain Generalization via Meta-Knowledge Encoding (COMEN), a general approach to automatically discover and model latent domains in two steps. Firstly, we introduce Style-induced Domain-specific Normalization (SDNorm) to re-normalize the multi-modal underlying distributions, thereby dividing the mixture of source domains into latent clusters. Secondly, we harness the prototype representations, the centroids of classes, to perform relational modeling in the embedding space with two parallel and complementary modules, which explicitly encode the semantic structure for the out-of-distribution generalization. Experiments on four standard DG benchmarks reveal that COMEN exceeds the state-of-the-art performance without the need of domain supervision.

Xiaoqing Liu, Kengo Araki, Shota Harada et al.

The domain shift in pathological segmentation is an important problem, where a network trained by a source domain (collected at a specific hospital) does not work well in the target domain (from different hospitals) due to the different image features. Due to the problems of class imbalance and different class prior of pathology, typical unsupervised domain adaptation methods do not work well by aligning the distribution of source domain and target domain. In this paper, we propose a cluster entropy for selecting an effective whole slide image (WSI) that is used for semi-supervised domain adaptation. This approach can measure how the image features of the WSI cover the entire distribution of the target domain by calculating the entropy of each cluster and can significantly improve the performance of domain adaptation. Our approach achieved competitive results against the prior arts on datasets collected from two hospitals.

Xiaoqing Liu, Kenji Ono, Ryoma Bise

The development of medical image segmentation using deep learning can significantly support doctors' diagnoses. Deep learning needs large amounts of data for training, which also requires data augmentation to extend diversity for preventing overfitting. However, the existing methods for data augmentation of medical image segmentation are mainly based on models which need to update parameters and cost extra computing resources. We proposed data augmentation methods designed to train a high accuracy deep learning network for medical image segmentation. The proposed data augmentation approaches are called KeepMask and KeepMix, which can create medical images by better identifying the boundary of the organ with no more parameters. Our methods achieved better performance and obtained more precise boundaries for medical image segmentation on datasets. The dice coefficient of our methods achieved 94.15% (3.04% higher than baseline) on CHAOS and 74.70% (5.25% higher than baseline) on MSD spleen with Unet.

Zhitao Zhu, Xili Wang, Shizhe Wu et al.

High-quality data is scarce in large language model (LLM) training, yet how to schedule its use jointly with training dynamics lacks theoretical guidance. We extend functional scaling laws by incorporating a data-quality dimension, and solve the joint data-quality and batch-size scheduling problem in asymptotic closed form. The solution reveals two regimes and a dual role of high-quality data. In the noise-limited regime, high-quality data should be used as a signal amplifier: lowering the batch size converts cleaner data into more signal without amplifying noise. In the signal-limited regime, it should be used as a noise suppressor: late placement reduces terminal noise without sacrificing signal accumulation. Existing curriculum-style pipelines primarily exploit the second role by placing cleaner data late, but miss the first role because conventional decay schedules reduce update intensity exactly when high-quality data becomes available. Guided by this, we propose Drop-Stable-Rampup for LLM midtraining: upon the quality transition, drop the batch size, hold it stable to accumulate signal, then ramp up to suppress terminal noise. On a 15B Mixture-of-Experts model midtrained on 108B tokens, Drop-Stable-Rampup improves average accuracy over Warmup-Stable-Decay (WSD) by +1.70 and over Cosine-decay by +2.98, with particularly large gains on mathematical reasoning benchmarks such as GSM8K (+4.23) and MATH (+2.80).

Meituan LongCat Team, Bayan, Bei Li et al.

We introduce LongCat-Flash, a 560-billion-parameter Mixture-of-Experts (MoE) language model designed for both computational efficiency and advanced agentic capabilities. Stemming from the need for scalable efficiency, LongCat-Flash adopts two novel designs: (a) Zero-computation Experts, which enables dynamic computational budget allocation and activates 18.6B-31.3B (27B on average) per token depending on contextual demands, optimizing resource usage. (b) Shortcut-connected MoE, which enlarges the computation-communication overlap window, demonstrating notable gains in inference efficiency and throughput compared to models of a comparable scale. We develop a comprehensive scaling framework for large models that combines hyperparameter transfer, model-growth initialization, a multi-pronged stability suite, and deterministic computation to achieve stable and reproducible training. Notably, leveraging the synergy among scalable architectural design and infrastructure efforts, we complete model training on more than 20 trillion tokens within 30 days, while achieving over 100 tokens per second (TPS) for inference at a cost of \$0.70 per million output tokens. To cultivate LongCat-Flash towards agentic intelligence, we conduct a large-scale pre-training on optimized mixtures, followed by targeted mid- and post-training on reasoning, code, and instructions, with further augmentation from synthetic data and tool use tasks. Comprehensive evaluations demonstrate that, as a non-thinking foundation model, LongCat-Flash delivers highly competitive performance among other leading models, with exceptional strengths in agentic tasks. The model checkpoint of LongCat-Flash is open-sourced to foster community research. LongCat Chat: https://longcat.ai Hugging Face: https://huggingface.co/meituan-longcat GitHub: https://github.com/meituan-longcat

Yifan Li, Arravind Subramanian, Xiaoqing Liu et al.

A central challenge in computational catalysis is the identification of low-energy and chemically plausible adsorption configurations, as these directly affect adsorption energies, reaction pathways, and catalytic performance. Existing approaches generally rely on enumerating candidate adsorption sites followed by iterative refinement through density functional theory calculations or machine-learning-based relaxations. However, such workflows remain computationally expensive and are difficult to scale to complex surfaces or multi-adsorbate systems. Here, we introduce Meta-LegNet, a graph learning framework that combines SE(3)-equivariant atom-level message passing with voxel-based multiscale aggregation and cross-domain meta-learning to learn transferable representations of local adsorption environments across diverse catalyst--adsorbate systems. Rather than following a conventional regression-only paradigm, Meta-LegNet encodes local chemical environments using invariant radial features and equivariant directional information, and further incorporates broader structural context through coordinate-frame voxel pooling, assignment-based upsampling, and gated feature fusion. The resulting local-global decomposition produces atom-resolved attribution maps, which are processed to identify adsorption-relevant local environments in an interpretable manner. Based on the learned representations, we further construct an adsorption-environment database and develop a template-matching strategy to propose likely adsorption sites on previously unexplored surfaces without exhaustive site enumeration. Overall, our results suggest that learning transferable adsorption environments provides an accurate, interpretable, and practical route for accelerating catalyst screening.

Changshang Xue, Xiande Zhong, Xiaoqing Liu

In recent years, a significant number of high-quality pretrained models have emerged, greatly impacting Natural Language Understanding (NLU), Natural Language Generation (NLG), and Text Representation tasks. Traditionally, these models are pretrained on custom domain corpora and finetuned for specific tasks, resulting in high costs related to GPU usage and labor. Unfortunately, recent trends in language modeling have shifted towards enhancing performance through scaling, further exacerbating the associated costs. Introducing GUR: a pretraining framework that combines language modeling and contrastive learning objectives in a single training step. We select similar text pairs based on their Longest Common Substring (LCS) from raw unlabeled documents and train the model using masked language modeling and unsupervised contrastive learning. The resulting model, GUR, achieves impressive results without any labeled training data, outperforming all other pretrained baselines as a retriever at the recall benchmark in a zero-shot setting. Additionally, GUR maintains its language modeling ability, as demonstrated in our ablation experiment. Our code is available at \url{https://github.com/laohur/GUR}.

Yuehan Jin, Xiaoqing Liu, Yiyuan Yang et al.

Multimodal emotion recognition analyzes emotions by combining data from multiple sources. However, real-world noise or sensor failures often cause missing or corrupted data, creating the Incomplete Multimodal Emotion Recognition (IMER) challenge. In this paper, we propose Robust Hybrid Diffusion Recovery (RoHyDR), a novel framework that performs missing-modality recovery at unimodal, multimodal, feature, and semantic levels. For unimodal representation recovery of missing modalities, RoHyDR exploits a diffusion-based generator to generate distribution-consistent and semantically aligned representations from Gaussian noise, using available modalities as conditioning. For multimodal fusion recovery, we introduce adversarial learning to produce a realistic fused multimodal representation and recover missing semantic content. We further propose a multi-stage optimization strategy that enhances training stability and efficiency. In contrast to previous work, the hybrid diffusion and adversarial learning-based recovery mechanism in RoHyDR allows recovery of missing information in both unimodal representation and multimodal fusion, at both feature and semantic levels, effectively mitigating performance degradation caused by suboptimal optimization. Comprehensive experiments conducted on two widely used multimodal emotion recognition benchmarks demonstrate that our proposed method outperforms state-of-the-art IMER methods, achieving robust recognition performance under various missing-modality scenarios. Our code will be made publicly available upon acceptance.

Jie Lian, Jingyu Liu, Shu Zhang et al.

Instance level detection and segmentation of thoracic diseases or abnormalities are crucial for automatic diagnosis in chest X-ray images. Leveraging on constant structure and disease relations extracted from domain knowledge, we propose a structure-aware relation network (SAR-Net) extending Mask R-CNN. The SAR-Net consists of three relation modules: 1. the anatomical structure relation module encoding spatial relations between diseases and anatomical parts. 2. the contextual relation module aggregating clues based on query-key pair of disease RoI and lung fields. 3. the disease relation module propagating co-occurrence and causal relations into disease proposals. Towards making a practical system, we also provide ChestX-Det, a chest X-Ray dataset with instance-level annotations (boxes and masks). ChestX-Det is a subset of the public dataset NIH ChestX-ray14. It contains ~3500 images of 13 common disease categories labeled by three board-certified radiologists. We evaluate our SAR-Net on it and another dataset DR-Private. Experimental results show that it can enhance the strong baseline of Mask R-CNN with significant improvements. The ChestX-Det is released at https://github.com/Deepwise-AILab/ChestX-Det-Dataset.

Meng Lou, Hanning Ying, Xiaoqing Liu et al.

Automated classification of liver lesions in multi-phase CT and MR scans is of clinical significance but challenging. This study proposes a novel Siamese Dual-Resolution Transformer (SDR-Former) framework, specifically designed for liver lesion classification in 3D multi-phase CT and MR imaging with varying phase counts. The proposed SDR-Former utilizes a streamlined Siamese Neural Network (SNN) to process multi-phase imaging inputs, possessing robust feature representations while maintaining computational efficiency. The weight-sharing feature of the SNN is further enriched by a hybrid Dual-Resolution Transformer (DR-Former), comprising a 3D Convolutional Neural Network (CNN) and a tailored 3D Transformer for processing high- and low-resolution images, respectively. This hybrid sub-architecture excels in capturing detailed local features and understanding global contextual information, thereby, boosting the SNN's feature extraction capabilities. Additionally, a novel Adaptive Phase Selection Module (APSM) is introduced, promoting phase-specific intercommunication and dynamically adjusting each phase's influence on the diagnostic outcome. The proposed SDR-Former framework has been validated through comprehensive experiments on two clinical datasets: a three-phase CT dataset and an eight-phase MR dataset. The experimental results affirm the efficacy of the proposed framework. To support the scientific community, we are releasing our extensive multi-phase MR dataset for liver lesion analysis to the public. This pioneering dataset, being the first publicly available multi-phase MR dataset in this field, also underpins the MICCAI LLD-MMRI Challenge. The dataset is accessible at:https://bit.ly/3IyYlgN.

Yueyang Wang, Jiawei Fu, Baolong Bi et al.

SWE-bench has emerged as the premier benchmark for evaluating Large Language Models on complex software engineering tasks. While these capabilities are fundamentally acquired during the mid-training phase and subsequently elicited during Supervised Fine-Tuning (SFT), there remains a critical deficit in metrics capable of guiding mid-training effectively. Standard metrics such as Perplexity (PPL) are compromised by the "Long-Context Tax" and exhibit weak correlation with downstream SWE performance. In this paper, we bridge this gap by first introducing a rigorous data filtering strategy. Crucially, we propose the Entropy Compression Hypothesis, redefining intelligence not by scalar Top-1 compression, but by the capacity to structure uncertainty into Entropy-Compressed States of low orders ("reasonable hesitation"). Grounded in this fine-grained entropy analysis, we formulate a novel metric, HE-SNR (High-Entropy Signal-to-Noise Ratio). Validated on industrial-scale Mixture-of-Experts (MoE) models across varying context windows (32K/128K), our approach demonstrates superior robustness and predictive power. This work provides both the theoretical foundation and practical tools for optimizing the latent potential of LLMs in complex engineering domains.

Xiaoqing Liu, Jitai Han, Hua Yan et al.

Placental abruption is a severe complication during pregnancy, and its early accurate diagnosis is crucial for ensuring maternal and fetal safety. Traditional ultrasound diagnostic methods heavily rely on physician experience, leading to issues such as subjective bias and diagnostic inconsistencies. This paper proposes an improved model, EH-YOLOv11n (Enhanced Hemorrhage-YOLOv11n), based on small-sample learning, aiming to achieve automatic detection of hematoma features in placental ultrasound images. The model enhances performance through multidimensional optimization: it integrates wavelet convolution and coordinate convolution to strengthen frequency and spatial feature extraction; incorporates a cascaded group attention mechanism to suppress ultrasound artifacts and occlusion interference, thereby improving bounding box localization accuracy. Experimental results demonstrate a detection accuracy of 78%, representing a 2.5% improvement over YOLOv11n and a 13.7% increase over YOLOv8. The model exhibits significant superiority in precision-recall curves, confidence scores, and occlusion scenarios. Combining high accuracy with real-time processing, this model provides a reliable solution for computer-aided diagnosis of placental abruption, holding significant clinical application value.

Zhaocheng Liu, Zhiwen Yu, Xiaoqing Liu

The heterogeneity of multimodal data leads to inconsistencies and imbalance, allowing a dominant modality to steer gradient updates. Existing solutions mainly focus on optimization- or data-based strategies but rarely exploit the information inherent in multimodal imbalance or conduct its quantitative analysis. To address this gap, we propose a novel quantitative analysis framework for Multimodal Imbalance and design a sample-level adaptive loss function. We define the Modality Gap as the Softmax score difference between modalities for the correct class and model its distribution using a bimodal Gaussian Mixture Model(GMM), representing balanced and imbalanced samples. Using Bayes' theorem, we estimate each sample's posterior probability of belonging to these two groups. Based on this, our adaptive loss (1) minimizes the overall Modality Gap, (2) aligns imbalanced samples with balanced ones, and (3) adaptively penalizes each according to its imbalance degree. A two-stage training strategy-warm-up and adaptive phases,yields state-of-the-art performance on CREMA-D (80.65%), AVE (70.40%), and KineticSound (72.42%). Fine-tuning with high-quality samples identified by the GMM further improves results, highlighting their value for effective multimodal fusion.

Gang Yu, Zhongzhi Yu, Yemin Shi et al.

Respiratory diseases, including asthma, bronchitis, pneumonia, and upper respiratory tract infection (RTI), are among the most common diseases in clinics. The similarities among the symptoms of these diseases precludes prompt diagnosis upon the patients' arrival. In pediatrics, the patients' limited ability in expressing their situation makes precise diagnosis even harder. This becomes worse in primary hospitals, where the lack of medical imaging devices and the doctors' limited experience further increase the difficulty of distinguishing among similar diseases. In this paper, a pediatric fine-grained diagnosis-assistant system is proposed to provide prompt and precise diagnosis using solely clinical notes upon admission, which would assist clinicians without changing the diagnostic process. The proposed system consists of two stages: a test result structuralization stage and a disease identification stage. The first stage structuralizes test results by extracting relevant numerical values from clinical notes, and the disease identification stage provides a diagnosis based on text-form clinical notes and the structured data obtained from the first stage. A novel deep learning algorithm was developed for the disease identification stage, where techniques including adaptive feature infusion and multi-modal attentive fusion were introduced to fuse structured and text data together. Clinical notes from over 12000 patients with respiratory diseases were used to train a deep learning model, and clinical notes from a non-overlapping set of about 1800 patients were used to evaluate the performance of the trained model. The average precisions (AP) for pneumonia, RTI, bronchitis and asthma are 0.878, 0.857, 0.714, and 0.825, respectively, achieving a mean AP (mAP) of 0.819.

Huangxing Lin, Yihong Zhuang, Yue Huang et al.

The effectiveness of existing denoising algorithms typically relies on accurate pre-defined noise statistics or plenty of paired data, which limits their practicality. In this work, we focus on denoising in the more common case where noise statistics and paired data are unavailable. Considering that denoising CNNs require supervision, we develop a new \textbf{adaptive noise imitation (ADANI)} algorithm that can synthesize noisy data from naturally noisy images. To produce realistic noise, a noise generator takes unpaired noisy/clean images as input, where the noisy image is a guide for noise generation. By imposing explicit constraints on the type, level and gradient of noise, the output noise of ADANI will be similar to the guided noise, while keeping the original clean background of the image. Coupling the noisy data output from ADANI with the corresponding ground-truth, a denoising CNN is then trained in a fully-supervised manner. Experiments show that the noisy data produced by ADANI are visually and statistically similar to real ones so that the denoising CNN in our method is competitive to other networks trained with external paired data.

Zhanwei Xu, Yukun Cao, Cheng Jin et al.

Segmentation of infected areas in chest CT volumes is of great significance for further diagnosis and treatment of COVID-19 patients. Due to the complex shapes and varied appearances of lesions, a large number of voxel-level labeled samples are generally required to train a lesion segmentation network, which is a main bottleneck for developing deep learning based medical image segmentation algorithms. In this paper, we propose a weakly-supervised lesion segmentation framework by embedding the Generative Adversarial training process into the Segmentation Network, which is called GASNet. GASNet is optimized to segment the lesion areas of a COVID-19 CT by the segmenter, and to replace the abnormal appearance with a generated normal appearance by the generator, so that the restored CT volumes are indistinguishable from healthy CT volumes by the discriminator. GASNet is supervised by chest CT volumes of many healthy and COVID-19 subjects without voxel-level annotations. Experiments on three public databases show that when using as few as one voxel-level labeled sample, the performance of GASNet is comparable to fully-supervised segmentation algorithms trained on dozens of voxel-level labeled samples.

Xiaoqing Liu, Yinyin Peng, Jie Wang et al.

Facebook is the online social networks (OSNs) platform with the largest number of users in the world today, information protection based on Facebook social network platform have important practical significance. Since the information users share on social networks is often based on images, this paper proposes a more secure image encryption algorithm based on Facebook social network platform to ensure the loss of information as much as possible. When the sender encrypts the image for uploading, it can first resist the third party's attack on the encrypted image and prevent the image data from leaking, simultaneously processed by some unknown processing such as compression and filtering of the image on the Facebook platform, the receiver can still decrypt the corresponding image data.

Huai Chen, Yuxiao Qi, Yong Yin et al.

Segmentation of nasopharyngeal carcinoma (NPC) from Magnetic Resonance Images (MRI) is a crucial prerequisite for NPC radiotherapy. However, manually segmenting of NPC is time-consuming and labor-intensive. Additionally, single-modality MRI generally cannot provide enough information for its accurate delineation. Therefore, a multi-modality MRI fusion network (MMFNet) based on three modalities of MRI (T1, T2 and contrast-enhanced T1) is proposed to complete accurate segmentation of NPC. The backbone of MMFNet is designed as a multi-encoder-based network, consisting of several encoders to capture modality-specific features and one single decoder to fuse them and obtain high-level features for NPC segmentation. A fusion block is presented to effectively fuse features from multi-modality MRI. It firstly recalibrates low-level features captured from modality-specific encoders to highlight both informative features and regions of interest, then fuses weighted features by a residual fusion block to keep balance between fused ones and high-level features from decoder. Moreover, a training strategy named self-transfer, which utilizes pre-trained modality-specific encoders to initialize multi-encoder-based network, is proposed to make full mining of information from different modalities of MRI. The proposed method based on multi-modality MRI can effectively segment NPC and its advantages are validated by extensive experiments.