Manuel Serna-Aguilera

Manuel Serna-Aguilera, Khoa Luu, Nathaniel Harris et al.

The biomedical imaging world is notorious for working with small amounts of data, frustrating state-of-the-art efforts in the computer vision and deep learning worlds. With large datasets, it is easier to make progress we have seen from the natural image distribution. It is the same with microscopy videos of neuron cells moving in a culture. This problem presents several challenges as it can be difficult to grow and maintain the culture for days, and it is expensive to acquire the materials and equipment. In this work, we explore how to alleviate this data scarcity problem by synthesizing the videos. We, therefore, take the recent work of the video diffusion model to synthesize videos of cells from our training dataset. We then analyze the model's strengths and consistent shortcomings to guide us on improving video generation to be as high-quality as possible. To improve on such a task, we propose modifying the denoising function and adding motion information (dense optical flow) so that the model has more context regarding how video frames transition over time and how each pixel changes over time.

Manuel Serna-Aguilera, Xuan Bac Nguyen, Han-Seok Seo et al.

Facial expressions and actions differ among different individuals at varying degrees of intensity given responses to external stimuli, particularly among those that are neurodivergent. Such behaviors affect people in terms of overall health, communication, and sensory processing. Deep learning can be responsibly leveraged to improve productivity in addressing this task, and help medical professionals to accurately understand such behaviors. In this work, we introduce the Video ASD dataset-a dataset that contains video frame convolutional and attention map feature data-to foster further progress in the task of ASD classification. Unlike many recent studies in ASD classification with MRI data, which require expensive specialized equipment, our method utilizes a powerful but relatively affordable GPU, a standard computer setup, and a video camera for inference. Results show that our model effectively generalizes and understands key differences in the distinct movements of the children. Additionally, we test foundation models on this data to showcase how movement noise affects performance and the need for more data and more complex labels.

M. Serna-Aguilera, X. B. Nguyen, A. Singh et al.

Individuals with Autism Spectrum Disorder (ASD) often experience challenges in health, communication, and sensory processing; therefore, early diagnosis is necessary for proper treatment and care. In this work, we consider the problem of detecting or classifying ASD children to aid medical professionals in early diagnosis. We develop a deep learning model that analyzes video clips of children reacting to sensory stimuli, with the intent of capturing key differences in reactions and behavior between ASD and non-ASD participants. Unlike many recent studies in ASD classification with MRI data, which require expensive specialized equipment, our method utilizes a powerful but relatively affordable GPU, a standard computer setup, and a video camera for inference. Results show that our model effectively generalizes and understands key differences in the distinct movements of the children. It is noteworthy that our model exhibits successful classification performance despite the limited amount of data for a deep learning problem and limited temporal information available for learning, even with the motion artifacts.