Quan Chen

Hamed Hooshangnejad, Xue Feng, Gaofeng Huang et al.

Lung cancer is a devastating disease with the highest mortality rate among cancer types. Over 60% of non-small cell lung cancer (NSCLC) patients, which accounts for 87% of diagnoses, require radiation therapy. Rapid treatment initiation significantly increases the patient's survival rate and reduces the mortality rate. Accurate tumor segmentation is a critical step in the diagnosis and treatment of NSCLC. Manual segmentation is time and labor-consuming and causes delays in treatment initiation. Although many lung nodule detection methods, including deep learning-based models, have been proposed, there is still a long-standing problem of high false positives (FPs) with most of these methods. Here, we developed an electronic health record (EHR) guided lung tumor auto-segmentation called EXACT-Net (EHR-enhanced eXACtitude in Tumor segmentation), where the extracted information from EHRs using a pre-trained large language model (LLM), was used to remove the FPs and keep the TP nodules only. The auto-segmentation model was trained on NSCLC patients' computed tomography (CT), and the pre-trained LLM was used with the zero-shot learning approach. Our approach resulted in a 250% boost in successful nodule detection using the data from ten NSCLC patients treated in our institution.

Bo Wang, Quan Chen, Min Zhou et al.

Feature matters for salient object detection. Existing methods mainly focus on designing a sophisticated structure to incorporate multi-level features and filter out cluttered features. We present Progressive Feature Polishing Network (PFPN), a simple yet effective framework to progressively polish the multi-level features to be more accurate and representative. By employing multiple Feature Polishing Modules (FPMs) in a recurrent manner, our approach is able to detect salient objects with fine details without any post-processing. A FPM parallelly updates the features of each level by directly incorporating all higher level context information. Moreover, it can keep the dimensions and hierarchical structures of the feature maps, which makes it flexible to be integrated with any CNN-based models. Empirical experiments show that our results are monotonically getting better with increasing number of FPMs. Without bells and whistles, PFPN outperforms the state-of-the-art methods significantly on five benchmark datasets under various evaluation metrics.

Liang Shen, Zihan Yue, Quan Chen et al.

Rain removal from a single image is a challenge which has been studied for a long time. In this paper, a novel convolutional neural network based on wavelet and dark channel is proposed. On one hand, we think that rain streaks correspond to high frequency component of the image. Therefore, haar wavelet transform is a good choice to separate the rain streaks and background to some extent. More specifically, the LL subband of a rain image is more inclined to express the background information, while LH, HL, HH subband tend to represent the rain streaks and the edges. On the other hand, the accumulation of rain streaks from long distance makes the rain image look like haze veil. We extract dark channel of rain image as a feature map in network. By increasing this mapping between the dark channel of input and output images, we achieve haze removal in an indirect way. All of the parameters are optimized by back-propagation. Experiments on both synthetic and real- world datasets reveal that our method outperforms other state-of- the-art methods from a qualitative and quantitative perspective.