Zabir Al Nazi

Zabir Al Nazi, Wei Peng

The deployment of large language models (LLMs) within the healthcare sector has sparked both enthusiasm and apprehension. These models exhibit the remarkable capability to provide proficient responses to free-text queries, demonstrating a nuanced understanding of professional medical knowledge. This comprehensive survey delves into the functionalities of existing LLMs designed for healthcare applications, elucidating the trajectory of their development, starting from traditional Pretrained Language Models (PLMs) to the present state of LLMs in healthcare sector. First, we explore the potential of LLMs to amplify the efficiency and effectiveness of diverse healthcare applications, particularly focusing on clinical language understanding tasks. These tasks encompass a wide spectrum, ranging from named entity recognition and relation extraction to natural language inference, multi-modal medical applications, document classification, and question-answering. Additionally, we conduct an extensive comparison of the most recent state-of-the-art LLMs in the healthcare domain, while also assessing the utilization of various open-source LLMs and highlighting their significance in healthcare applications. Furthermore, we present the essential performance metrics employed to evaluate LLMs in the biomedical domain, shedding light on their effectiveness and limitations. Finally, we summarize the prominent challenges and constraints faced by large language models in the healthcare sector, offering a holistic perspective on their potential benefits and shortcomings. This review provides a comprehensive exploration of the current landscape of LLMs in healthcare, addressing their role in transforming medical applications and the areas that warrant further research and development.

Zabir Al Nazi, Shubhashis Roy Dipta, Sudipta Kar

Chain-of-Thought (CoT) prompting is widely adopted for mathematical problem solving, including in low-resource languages, yet its behavior under irrelevant context remains underexplored. To systematically study this challenge, we introduce DISTRACTMATH-BN, a Bangla benchmark that augments MGSM and MSVAMP with semantically coherent but computationally irrelevant information. Evaluating seven models ranging from 3B to 12B parameters, we observe substantial performance degradation under distractors: standard models drop by up to 41 points, while reasoning-specialized models decline by 14 to 20 points despite consuming five times more tokens. We propose †DAGGER, which reformulates mathematical problem solving as executable computational graph generation with explicit modeling of distractor nodes. Fine-tuning Gemma-3 models using supervised fine-tuning followed by Group Relative Policy Optimization achieves comparable weighted accuracy on augmented benchmarks while using 89 percent fewer tokens than reasoning models. Importantly, this robustness emerges without explicit training on distractor-augmented examples. Our results suggest that enforcing structured intermediate representations improves robustness and inference efficiency in mathematical reasoning compared to free-form approaches, particularly in noisy, low-resource settings.

Zabir Al Nazi, GM Shahariar, Md. Abrar Hossain et al.

Theory of Mind (ToM) - the ability to attribute beliefs and intents to others - is fundamental for social intelligence, yet Vision-Language Model (VLM) evaluations remain largely Western-centric. In this work, we introduce CulturalToM-VQA, a benchmark of 5,095 visually situated ToM probes across diverse cultural contexts, rituals, and social norms. Constructed through a frontier proprietary MLLM, human-verified pipeline, the dataset spans a taxonomy of six ToM tasks and four complexity levels. We benchmark 10 VLMs (2023-2025) and observe a significant performance leap: while earlier models struggle, frontier models achieve high accuracy (>93%). However, significant limitations persist: models struggle with false belief reasoning (19-83% accuracy) and show high regional variance (20-30% gaps). Crucially, we find that SOTA models exhibit social desirability bias - systematically favoring semantically positive answer choices over negative ones. Ablation experiments reveal that some frontier models rely heavily on parametric social priors, frequently defaulting to safety-aligned predictions. Furthermore, while Chain-of-Thought prompting aids older models, it yields minimal gains for newer ones. Overall, our work provides a testbed for cross-cultural social reasoning, underscoring that despite architectural gains, achieving robust, visually grounded understanding remains an open challenge.

Zabir Al Nazi, Sayed Mohammed Tasmimul Huda

Speech synthesis is one of the challenging tasks to automate by deep learning, also being a low-resource language there are very few attempts at Bangla speech synthesis. Most of the existing works can't work with anything other than simple Bangla characters script, very short sentences, etc. This work attempts to solve these problems by introducing Byakta, the first-ever open-source deep learning-based bilingual (Bangla and English) text to a speech synthesis system. A speech recognition model-based automated scoring metric was also proposed to evaluate the performance of a TTS model. We also introduce a test benchmark dataset for Bangla speech synthesis models for evaluating speech quality. The TTS is available at https://github.com/zabir-nabil/bangla-tts

Zabir Al Nazi, Fazla Rabbi Mashrur, Md Amirul Islam et al.

Idiopathic pulmonary fibrosis (IPF) is a restrictive interstitial lung disease that causes lung function decline by lung tissue scarring. Although lung function decline is assessed by the forced vital capacity (FVC), determining the accurate progression of IPF remains a challenge. To address this challenge, we proposed Fibro-CoSANet, a novel end-to-end multi-modal learning-based approach, to predict the FVC decline. Fibro-CoSANet utilized CT images and demographic information in convolutional neural network frameworks with a stacked attention layer. Extensive experiments on the OSIC Pulmonary Fibrosis Progression Dataset demonstrated the superiority of our proposed Fibro-CoSANet by achieving the new state-of-the-art modified Laplace Log-Likelihood score of -6.68. This network may benefit research areas concerned with designing networks to improve the prognostic accuracy of IPF. The source-code for Fibro-CoSANet is available at: \url{https://github.com/zabir-nabil/Fibro-CoSANet}.

Zabir Al Nazi, Vagelis Hristidis, Aaron Lawson McLean et al.

Effective Question Answering (QA) on large biomedical document collections requires effective document retrieval techniques. The latter remains a challenging task due to the domain-specific vocabulary and semantic ambiguity in user queries. We propose BMQExpander, a novel ontology-aware query expansion pipeline that combines medical knowledge - definitions and relationships - from the UMLS Metathesaurus with the generative capabilities of large language models (LLMs) to enhance retrieval effectiveness. We implemented several state-of-the-art baselines, including sparse and dense retrievers, query expansion methods, and biomedical-specific solutions. We show that BMQExpander has superior retrieval performance on three popular biomedical Information Retrieval (IR) benchmarks: NFCorpus, TREC-COVID, and SciFact - with improvements of up to 22.1% in NDCG@10 over sparse baselines and up to 6.5% over the strongest baseline. Further, BMQExpander generalizes robustly under query perturbation settings, in contrast to supervised baselines, achieving up to 15.7% improvement over the strongest baseline. As a side contribution, we publish our paraphrased benchmarks. Finally, our qualitative analysis shows that BMQExpander has fewer hallucinations compared to other LLM-based query expansion baselines.