Deepak Mishra

Vandan Gorade, Azad Singh, Deepak Mishra

Learning representation from unlabeled time series data is a challenging problem. Most existing self-supervised and unsupervised approaches in the time-series domain do not capture low and high-frequency features at the same time. Further, some of these methods employ large scale models like transformers or rely on computationally expensive techniques such as contrastive learning. To tackle these problems, we propose a non-contrastive self-supervised learning approach efficiently captures low and high-frequency time-varying features in a cost-effective manner. Our method takes raw time series data as input and creates two different augmented views for two branches of the model, by randomly sampling the augmentations from same family. Following the terminology of BYOL, the two branches are called online and target network which allows bootstrapping of the latent representation. In contrast to BYOL, where a backbone encoder is followed by multilayer perceptron (MLP) heads, the proposed model contains additional temporal convolutional network (TCN) heads. As the augmented views are passed through large kernel convolution blocks of the encoder, the subsequent combination of MLP and TCN enables an effective representation of low as well as high-frequency time-varying features due to the varying receptive fields. The two modules (MLP and TCN) act in a complementary manner. We train an online network where each module learns to predict the outcome of the respective module of target network branch. To demonstrate the robustness of our model we performed extensive experiments and ablation studies on five real-world time-series datasets. Our method achieved state-of-art performance on all five real-world datasets.

Aiman Farooq, Deepak Mishra, Santanu Chaudhury

Survival prediction is a crucial task associated with cancer diagnosis and treatment planning. This paper presents a novel approach to survival prediction by harnessing comprehensive information from CT and PET scans, along with associated Genomic data. Current methods rely on either a single modality or the integration of multiple modalities for prediction without adequately addressing associations across patients or modalities. We aim to develop a robust predictive model for survival outcomes by integrating multi-modal imaging data with genetic information while accounting for associations across patients and modalities. We learn representations for each modality via a self-supervised module and harness the semantic similarities across the patients to ensure the embeddings are aligned closely. However, optimizing solely for global relevance is inadequate, as many pairs sharing similar high-level semantics, such as tumor type, are inadvertently pushed apart in the embedding space. To address this issue, we use a cross-patient module (CPM) designed to harness inter-subject correspondences. The CPM module aims to bring together embeddings from patients with similar disease characteristics. Our experimental evaluation of the dataset of Non-Small Cell Lung Cancer (NSCLC) patients demonstrates the effectiveness of our approach in predicting survival outcomes, outperforming state-of-the-art methods.

Aiman Farooq, Deepak Mishra, Santanu Chaudhury

In this study, we present a novel approach for predicting genomic information from medical imaging modalities using a transformer-based model. We aim to bridge the gap between imaging and genomics data by leveraging transformer networks, allowing for accurate genomic profile predictions from CT/MRI images. Presently most studies rely on the use of whole slide images (WSI) for the association, which are obtained via invasive methodologies. We propose using only available CT/MRI images to predict genomic sequences. Our transformer based approach is able to efficiently generate associations between multiple sequences based on CT/MRI images alone. This work paves the way for the use of non-invasive imaging modalities for precise and personalized healthcare, allowing for a better understanding of diseases and treatment.

Harini G., Aiman Farooq, Deepak Mishra

Thoracic trauma often results in rib fractures, which demand swift and accurate diagnosis for effective treatment. However, detecting these fractures on rib CT scans poses considerable challenges, involving the analysis of many image slices in sequence. Despite notable advancements in algorithms for automated fracture segmentation, the persisting challenges stem from the diverse shapes and sizes of these fractures. To address these issues, this study introduces a sophisticated deep-learning model with an auxiliary classification task designed to enhance the accuracy of rib fracture segmentation. The auxiliary classification task is crucial in distinguishing between fractured ribs and negative regions, encompassing non-fractured ribs and surrounding tissues, from the patches obtained from CT scans. By leveraging this auxiliary task, the model aims to improve feature representation at the bottleneck layer by highlighting the regions of interest. Experimental results on the RibFrac dataset demonstrate significant improvement in segmentation performance.

Aiman Farooq, Utkarsh Sharma, Deepak Mishra

Accurate survival prediction in head and neck cancer (HNC) is essential for guiding clinical decision-making and optimizing treatment strategies. Traditional models, such as Cox proportional hazards, have been widely used but are limited in their ability to handle complex multi-modal data. This paper proposes a deep learning-based approach leveraging CT and PET imaging modalities to predict survival outcomes in HNC patients. Our method integrates feature extraction with a Convolutional Block Attention Module (CBAM) and a multi-modal data fusion layer that combines imaging data to generate a compact feature representation. The final prediction is achieved through a fully parametric discrete-time survival model, allowing for flexible hazard functions that overcome the limitations of traditional survival models. We evaluated our approach using the HECKTOR and HEAD-NECK-RADIOMICS- HN1 datasets, demonstrating its superior performance compared to conconventional statistical and machine learning models. The results indicate that our deep learning model significantly improves survival prediction accuracy, offering a robust tool for personalized treatment planning in HNC

Deepan Das, Deepak Mishra

We present an improved clustering based, unsupervised anomalous trajectory detection algorithm for crowded scenes. The proposed work is based on four major steps, namely, extraction of trajectories from crowded scene video, extraction of several features from these trajectories, independent mean-shift clustering and anomaly detection. First, the trajectories of all moving objects in a crowd are extracted using a multi feature video object tracker. These trajectories are then transformed into a set of feature spaces. Mean shift clustering is applied on these feature matrices to obtain distinct clusters, while a Shannon Entropy based anomaly detector identifies corresponding anomalies. In the final step, a voting mechanism identifies the trajectories that exhibit anomalous characteristics. The algorithm is tested on crowd scene videos from datasets. The videos represent various possible crowd scenes with different motion patterns and the method performs well to detect the expected anomalous trajectories from the scene.

Arnab Karmakar, Deepak Mishra, Anandmayee Tej

Detecting stellar clusters have always been an important research problem in Astronomy. Although images do not convey very detailed information in detecting stellar density enhancements, we attempt to understand if new machine learning techniques can reveal patterns that would assist in drawing better inferences from the available image data. This paper describes an unsupervised approach in detecting star clusters using Deep Variational Autoencoder combined with a Gaussian Mixture Model. We show that our method works significantly well in comparison with state-of-the-art detection algorithm in recognizing a variety of star clusters even in the presence of noise and distortion.

Deepak Mishra, Rajeev Ranjan, Santanu Chaudhury et al.

Image registration is a process of aligning two or more images of same objects using geometric transformation. Most of the existing approaches work on the assumption of location invariance. These approaches require object-centric images to perform matching. Further, in absence of intensity level symmetry between the corresponding points in two images, the learning based registration approaches rely on synthetic deformations, which often fail in real scenarios. To address these issues, a combination of convolutional neural networks (CNNs) to perform the desired registration is developed in this work. The complete objective is divided into three sub-objectives: object localization, segmentation and matching transformation. Object localization step establishes an initial correspondence between the images. A modified version of single shot multi-box detector is used for this purpose. The detected region is cropped to make the images object-centric. Subsequently, the objects are segmented and matched using a spatial transformer network employing thin plate spline deformation. Initial experiments on MNIST and Caltech-101 datasets show that the proposed model is able to produce accurate matching. Quantitative evaluation performed using dice coefficient (DC) and mean intersection over union (mIoU) show that proposed method results in the values of 79% and 66%, respectively for MNIST dataset and the values of 94% and 90%, respectively for Caltech-101 dataset. The proposed framework is extended to the registration of CT and US images, which is free from any data specific assumptions and has better generalization capability as compared to the existing rule-based/classical approaches.

Litu Rout, Sidhartha, Gorthi R. K. S. S. Manyam et al.

Visual Object tracking research has undergone significant improvement in the past few years. The emergence of tracking by detection approach in tracking paradigm has been quite successful in many ways. Recently, deep convolutional neural networks have been extensively used in most successful trackers. Yet, the standard approach has been based on correlation or feature selection with minimal consideration given to motion consistency. Thus, there is still a need to capture various physical constraints through motion consistency which will improve accuracy, robustness and more importantly rotation adaptiveness. Therefore, one of the major aspects of this paper is to investigate the outcome of rotation adaptiveness in visual object tracking. Among other key contributions, the paper also includes various consistencies that turn out to be extremely effective in numerous challenging sequences than the current state-of-the-art.

Agrima Seth, Deepak Mishra

This is a comparative study of the traditional 3D computer graphics technique of geometric modelling and image-based rendering techniques that were surveyed and implemented.We have discussed the classifications and representative methods of both the techniques. The study has shown that there is a strong continuum between both the techniques and a hybrid of the two is most suitable for further implementations.This hybridisation study is underway to create models of real life situations and provide disaster management training.