Zhongliang Fu

Yaoyao Zhu, Xiuding Cai, Xueyao Wang et al.

Data augmentation is a crucial regularization technique for deep neural networks, particularly in medical image classification. Mainstream data augmentation (DA) methods are usually applied at the image level. Due to the specificity and diversity of medical imaging, expertise is often required to design effective DA strategies, and improper augmentation operations can degrade model performance. Although automatic augmentation methods exist, they are computationally intensive. Semantic data augmentation can implemented by translating features in feature space. However, over-translation may violate the image label. To address these issues, we propose \emph{Bayesian Random Semantic Data Augmentation} (BSDA), a computationally efficient and handcraft-free feature-level DA method. BSDA uses variational Bayesian to estimate the distribution of the augmentable magnitudes, and then a sample from this distribution is added to the original features to perform semantic data augmentation. We performed experiments on nine 2D and five 3D medical image datasets. Experimental results show that BSDA outperforms current DA methods. Additionally, BSDA can be easily assembled into CNNs or Transformers as a plug-and-play module, improving the network's performance. The code is available online at \url{https://github.com/YaoyaoZhu19/BSDA}.

Yaoyao Zhu, Xiuding Cai, Yingkai Wang et al.

Deep learning models excel in computer vision tasks but often fail to generalize to out-of-distribution (OOD) domains. Invariant Risk Minimization (IRM) aims to address OOD generalization by learning domain-invariant features. However, IRM struggles with datasets exhibiting significant diversity shifts. While data augmentation methods like Mixup and Semantic Data Augmentation (SDA) enhance diversity, they risk over-augmentation and label instability. To address these challenges, we propose a domain-shared Semantic Data Augmentation (SDA) module, a novel implementation of Variance Risk Minimization (VRM) designed to enhance dataset diversity while maintaining label consistency. We further provide a Rademacher complexity analysis, establishing a tighter generalization error bound compared to baseline methods. Extensive evaluations on OOD benchmarks, including PACS, VLCS, OfficeHome, and TerraIncognita, demonstrate consistent performance improvements over state-of-the-art domain generalization methods.

Yaoyao Zhu, Xiuding Cai, Yingkai Wang et al.

Deep learning has achieved remarkable success in medical image classification. However, its clinical application is often hindered by data heterogeneity caused by variations in scanner vendors, imaging protocols, and operators. Approaches such as invariant risk minimization (IRM) aim to address this challenge of out-of-distribution generalization. For instance, VIRM improves upon IRM by tackling the issue of insufficient feature support overlap, demonstrating promising potential. Nonetheless, these methods face limitations in medical imaging due to the scarcity of annotated data and the inefficiency of augmentation strategies. To address these issues, we propose a novel domain-oriented direction selector to replace the random augmentation strategy used in VIRM. Our method leverages inter-domain covariance as a guider for augmentation direction, guiding data augmentation towards the target domain. This approach effectively reduces domain discrepancies and enhances generalization performance. Experiments on a multi-center diabetic retinopathy dataset demonstrate that our method outperforms state-of-the-art approaches, particularly under limited data conditions and significant domain heterogeneity.