Ana Kenney

Abhineet Agarwal, Ana M. Kenney, Yan Shuo Tan et al. · berkeley

Random forests (RFs) are among the most popular supervised learning algorithms due to their nonlinear flexibility and ease-of-use. However, as black box models, they can only be interpreted via algorithmically-defined feature importance methods, such as Mean Decrease in Impurity (MDI), which have been observed to be highly unstable and have ambiguous scientific meaning. Furthermore, they can perform poorly in the presence of smooth or additive structure. To address this, we reinterpret decision trees and MDI as linear regression and $R^2$ values, respectively, with respect to engineered features associated with the tree's decision splits. This allows us to combine the respective strengths of RFs and generalized linear models in a framework called RF+, which also yields an improved feature importance method we call MDI+. Through extensive data-inspired simulations and real-world datasets, we show that RF+ improves prediction accuracy over RFs and that MDI+ outperforms popular feature importance measures in identifying signal features, often yielding more than a 10% improvement over its closest competitor. In case studies on drug response prediction and breast cancer subtyping, we further show that MDI+ extracts well-established genes with significantly greater stability compared to existing feature importance measures.

Jordan Awan, Ana Kenney, Matthew Reimherr et al.

The exponential mechanism is a fundamental tool of Differential Privacy (DP) due to its strong privacy guarantees and flexibility. We study its extension to settings with summaries based on infinite dimensional outputs such as with functional data analysis, shape analysis, and nonparametric statistics. We show that one can design the mechanism with respect to a specific base measure over the output space, such as a Guassian process. We provide a positive result that establishes a Central Limit Theorem for the exponential mechanism quite broadly. We also provide an apparent negative result, showing that the magnitude of the noise introduced for privacy is asymptotically non-negligible relative to the statistical estimation error. We develop an \ep-DP mechanism for functional principal component analysis, applicable in separable Hilbert spaces. We demonstrate its performance via simulations and applications to two datasets.