Selin Aslan

Selin Aslan, Eric de Sturler, Misha E. Kilmer

In partial differential equations-based (PDE-based) inverse problems with many measurements, many large-scale discretized PDEs must be solved for each evaluation of the misfit or objective function. In the nonlinear case, evaluating the Jacobian requires solving an additional set of systems. This leads to a tremendous computational cost, and this is by far the dominant cost for these problems. Several authors have proposed randomization and stochastic programming techniques to drastically reduce the number of system solves by estimating the objective function using only a few appropriately chosen random linear combinations of the sources. While some have reported good solution quality at a greatly reduced cost, for our problem of interest, diffuse optical tomography, the approach often does not lead to sufficiently accurate solutions. We propose two improvements. First, to efficiently exploit Newton-type methods, we modify the stochastic estimates to include random linear combinations of detectors, drastically reducing the number of adjoint solves. Second, after solving to a modest tolerance, we compute a few simultaneous sources and detectors that maximize the Frobenius norm of the sampled Jacobian to improve the rate of convergence and obtain more accurate solutions. We complement these optimized simultaneous sources and detectors by random simultaneous sources and detectors constrained to a complementary subspace. Our approach leads to solutions of the same quality as obtained using all sources and detectors but at a greatly reduced computational cost, as the number of large-scale linear systems to be solved is significantly reduced.

Selin Aslan, Tristan van Leeuwen, Allard Mosk et al.

In phase retrieval and similar inverse problems, the stability of solutions across different noise levels is crucial for applications. One approach to promote it is using signal priors in a form of a generative model as a regularization, at the expense of introducing a bias in the reconstruction. In this paper, we explore and compare the reconstruction properties of classical and generative inverse problem formulations. We propose a new unified reconstruction approach that mitigates overfitting to the generative model for varying noise levels.

Soumendu Majee, Selin Aslan, Doga Gursoy et al.

In many computed tomography (CT) imaging applications, it is important to rapidly collect data from an object that is moving or changing with time. Tomographic acquisition is generally assumed to be step-and-shoot, where the object is rotated to each desired angle, and a view is taken. However, step-and-shoot acquisition is slow and can waste photons, so in practice fly-scanning is done where the object is continuously rotated while collecting data. However, this can result in motion-blurred views and consequently reconstructions with severe motion artifacts. In this paper, we introduce CodEx, a modular framework for joint de-blurring and tomographic reconstruction that can effectively invert the motion blur introduced in sparse view fly-scanning. The method is a synergistic combination of a novel acquisition method with a novel non-convex Bayesian reconstruction algorithm. CodEx works by encoding the acquisition with a known binary code that the reconstruction algorithm then inverts. Using a well chosen binary code to encode the measurements can improve the accuracy of the inversion process. The CodEx reconstruction method uses the alternating direction method of multipliers (ADMM) to split the inverse problem into iterative deblurring and reconstruction sub-problems, making reconstruction practical to implement. We present reconstruction results on both simulated and binned experimental data to demonstrate the effectiveness of our method.