Xi Lu

Zhe Li, Ronghui Xu, Jilin Hu et al.

Significant wave height (SWH) is a vital metric in marine science, and accurate SWH estimation is crucial for various applications, e.g., marine energy development, fishery, early warning systems for potential risks, etc. Traditional SWH estimation methods that are based on numerical models and physical theories are hindered by computational inefficiencies. Recently, machine learning has emerged as an appealing alternative to improve accuracy and reduce computational time. However, due to limited observational technology and high costs, the scarcity of real-world data restricts the potential of machine learning models. To overcome these limitations, we propose an ocean SWH estimation framework, namely Orca. Specifically, Orca enhances the limited spatio-temporal reasoning abilities of classic LLMs with a novel spatiotemporal aware encoding module. By segmenting the limited buoy observational data temporally, encoding the buoys' locations spatially, and designing prompt templates, Orca capitalizes on the robust generalization ability of LLMs to estimate significant wave height effectively with limited data. Experimental results on the Gulf of Mexico demonstrate that Orca achieves state-of-the-art performance in SWH estimation.

Jiangwei Mo, Xi Lu, Hanlin Wu

High-resolution remote sensing images (RSIs) are crucial for Earth observation applications, yet acquiring them is often limited by sensor constraints and costs. In recent years, generative super-resolution (SR) methods, particularly diffusion models, have made significant progress. However, they typically require slow iterative inference with 40--1000 steps and exhibit limited flexibility in continuous-scale SR settings. To address these issues, we propose FlowGS, a generative reconstruction framework for arbitrary-scale SR of RSIs. FlowGS models the high-frequency detail representations between high- and low-resolution images and learns a continuous probability flow from noise to detail priors via flow matching (FM) constrained by shortcut consistency, thereby reducing generative complexity and improving inference efficiency. Additionally, we employ 2D Gaussian splatting to construct a continuous feature field, thereby enabling flexible reconstruction at arbitrary query locations. Experimental results show that FlowGS delivers competitive perceptual quality compared with existing methods in both continuous-scale and fixed-scale SR settings, with substantially improved inference efficiency.

Xi Lu, Di Hu, An T. Nguyen et al.

Patient-controlled data-sharing systems are increasingly promoted as a way to empower patients with greater autonomy over their health data. Yet it remains unclear how different stakeholders, especially patients and health system leaders, perceive the benefits and challenges of enabling granular control over the sharing of de-identified medical data for research. To address this gap, we developed a high-fidelity prototype of a patient-controlled, web-based consent platform and conducted a two-phase mixed-methods study:semi-structured interviews with 16 health system leaders and a survey with 523 patient participants. While both groups appreciated the potential of such a platform to enhance transparency and autonomy, their views diverged in meaningful ways. Leaders viewed transparency and granular control through the lens of informed consent and institutional ethics, whereas patients interpreted these factors as safeguards against potential risks and uncertainties. Our findings underscore critical tensions such as individual control and research integrity. We offer design implications for building trustworthy, context-aware systems that support flexible granularity, provide ongoing benefit-centered transparency, and adapt to diverse literacy and privacy needs.

Junhao Cheng, Baiqiao Yin, Kaixin Cai et al.

Recent advances in diffusion models can generate high-quality and stunning images from text. However, multi-turn image generation, which is of high demand in real-world scenarios, still faces challenges in maintaining semantic consistency between images and texts, as well as contextual consistency of the same subject across multiple interactive turns. To address this issue, we introduce TheaterGen, a training-free framework that integrates large language models (LLMs) and text-to-image (T2I) models to provide the capability of multi-turn image generation. Within this framework, LLMs, acting as a "Screenwriter", engage in multi-turn interaction, generating and managing a standardized prompt book that encompasses prompts and layout designs for each character in the target image. Based on these, Theatergen generate a list of character images and extract guidance information, akin to the "Rehearsal". Subsequently, through incorporating the prompt book and guidance information into the reverse denoising process of T2I diffusion models, Theatergen generate the final image, as conducting the "Final Performance". With the effective management of prompt books and character images, TheaterGen significantly improves semantic and contextual consistency in synthesized images. Furthermore, we introduce a dedicated benchmark, CMIGBench (Consistent Multi-turn Image Generation Benchmark) with 8000 multi-turn instructions. Different from previous multi-turn benchmarks, CMIGBench does not define characters in advance. Both the tasks of story generation and multi-turn editing are included on CMIGBench for comprehensive evaluation. Extensive experimental results show that TheaterGen outperforms state-of-the-art methods significantly. It raises the performance bar of the cutting-edge Mini DALLE 3 model by 21% in average character-character similarity and 19% in average text-image similarity.

Junhao Cheng, Wei-Ting Chen, Xi Lu et al.

Generative diffusion models trained on large-scale datasets have achieved remarkable progress in image synthesis. In favor of their ability to supplement missing details and generate aesthetically pleasing contents, recent works have applied them to image deblurring via training an adapter on blurry-sharp image pairs to provide structural conditions for restoration. However, acquiring substantial amounts of realistic paired data is challenging and costly in real-world scenarios. On the other hand, relying solely on synthetic data often results in overfitting, leading to unsatisfactory performance when confronted with unseen blur patterns. To tackle this issue, we propose UID-Diff, a generative-diffusion-based model designed to enhance deblurring performance on unknown domains by decoupling structural features and blur patterns through joint training on three specially designed tasks. We employ two Q-Formers as structural features and blur patterns extractors separately. The features extracted by them will be used for the supervised deblurring task on synthetic data and the unsupervised blur-transfer task by leveraging unpaired blurred images from the target domain simultaneously. We further introduce a reconstruction task to make the structural features and blur patterns complementary. This blur-decoupled learning process enhances the generalization capabilities of UID-Diff when encountering unknown blur patterns. Experiments on real-world datasets demonstrate that UID-Diff outperforms existing state-of-the-art methods in blur removal and structural preservation in various challenging scenarios.

Shiyue Zhang, Zheng Chong, Xi Lu et al.

Building on the success of diffusion models, significant advancements have been made in multimodal image generation tasks. Among these, human image generation has emerged as a promising technique, offering the potential to revolutionize the fashion design process. However, existing methods often focus solely on text-to-image or image reference-based human generation, which fails to satisfy the increasingly sophisticated demands. To address the limitations of flexibility and precision in human generation, we introduce ComposeAnyone, a controllable layout-to-human generation method with decoupled multimodal conditions. Specifically, our method allows decoupled control of any part in hand-drawn human layouts using text or reference images, seamlessly integrating them during the generation process. The hand-drawn layout, which utilizes color-blocked geometric shapes such as ellipses and rectangles, can be easily drawn, offering a more flexible and accessible way to define spatial layouts. Additionally, we introduce the ComposeHuman dataset, which provides decoupled text and reference image annotations for different components of each human image, enabling broader applications in human image generation tasks. Extensive experiments on multiple datasets demonstrate that ComposeAnyone generates human images with better alignment to given layouts, text descriptions, and reference images, showcasing its multi-task capability and controllability.

Junhao Cheng, Xi Lu, Hanhui Li et al.

As cutting-edge Text-to-Image (T2I) generation models already excel at producing remarkable single images, an even more challenging task, i.e., multi-turn interactive image generation begins to attract the attention of related research communities. This task requires models to interact with users over multiple turns to generate a coherent sequence of images. However, since users may switch subjects frequently, current efforts struggle to maintain subject consistency while generating diverse images. To address this issue, we introduce a training-free multi-agent framework called AutoStudio. AutoStudio employs three agents based on large language models (LLMs) to handle interactions, along with a stable diffusion (SD) based agent for generating high-quality images. Specifically, AutoStudio consists of (i) a subject manager to interpret interaction dialogues and manage the context of each subject, (ii) a layout generator to generate fine-grained bounding boxes to control subject locations, (iii) a supervisor to provide suggestions for layout refinements, and (iv) a drawer to complete image generation. Furthermore, we introduce a Parallel-UNet to replace the original UNet in the drawer, which employs two parallel cross-attention modules for exploiting subject-aware features. We also introduce a subject-initialized generation method to better preserve small subjects. Our AutoStudio hereby can generate a sequence of multi-subject images interactively and consistently. Extensive experiments on the public CMIGBench benchmark and human evaluations show that AutoStudio maintains multi-subject consistency across multiple turns well, and it also raises the state-of-the-art performance by 13.65% in average Frechet Inception Distance and 2.83% in average character-character similarity.

Jinjiang Guo, Qi Liu, Han Guo et al.

Robust and efficient interpretation of QSAR methods is quite useful to validate AI prediction rationales with subjective opinion (chemist or biologist expertise), understand sophisticated chemical or biological process mechanisms, and provide heuristic ideas for structure optimization in pharmaceutical industry. For this purpose, we construct a multi-layer self-attention based Graph Neural Network framework, namely Ligandformer, for predicting compound property with interpretation. Ligandformer integrates attention maps on compound structure from different network blocks. The integrated attention map reflects the machine's local interest on compound structure, and indicates the relationship between predicted compound property and its structure. This work mainly contributes to three aspects: 1. Ligandformer directly opens the black-box of deep learning methods, providing local prediction rationales on chemical structures. 2. Ligandformer gives robust prediction in different experimental rounds, overcoming the ubiquitous prediction instability of deep learning methods. 3. Ligandformer can be generalized to predict different chemical or biological properties with high performance. Furthermore, Ligandformer can simultaneously output specific property score and visible attention map on structure, which can support researchers to investigate chemical or biological property and optimize structure efficiently. Our framework outperforms over counterparts in terms of accuracy, robustness and generalization, and can be applied in complex system study.