Yue Su

Xin Sun, Yue Su, Yifan Mo et al.

Building trustworthy AI systems for mental health support is a shared priority across stakeholders from multiple disciplines. However, "trustworthy" remains loosely defined and inconsistently operationalized. AI research often focuses on technical criteria (e.g., robustness, explainability, and safety), while therapeutic practitioners emphasize therapeutic fidelity (e.g., appropriateness, empathy, and long-term user outcomes). To bridge the fragmented landscape, we propose a three-layer trust framework, covering human-oriented, AI-oriented, and interaction-oriented trust, integrating the viewpoints of key stakeholders (e.g., practitioners, researchers, regulators). Using this framework, we systematically review existing AI-driven research in mental health domain and examine evaluation practices for ``trustworthy'' ranging from automatic metrics to clinically validated approaches. We highlight critical gaps between what NLP currently measures and what real-world mental health contexts require, and outline a research agenda for building socio-technically aligned and genuinely trustworthy AI for mental health support.

Boqin Yuan, Yue Su, Kun Yao

Memory-augmented LLM agents store and retrieve information from prior interactions, yet the relative importance of how memories are written versus how they are retrieved remains unclear. We introduce a diagnostic framework that analyzes how performance differences manifest across write strategies, retrieval methods, and memory utilization behavior, and apply it to a 3x3 study crossing three write strategies (raw chunks, Mem0-style fact extraction, MemGPT-style summarization) with three retrieval methods (cosine, BM25, hybrid reranking). On LoCoMo, retrieval method is the dominant factor: average accuracy spans 20 points across retrieval methods (57.1% to 77.2%) but only 3-8 points across write strategies. Raw chunked storage, which requires zero LLM calls, matches or outperforms expensive lossy alternatives, suggesting that current memory pipelines may discard useful context that downstream retrieval mechanisms fail to compensate for. Failure analysis shows that performance breakdowns most often manifest at the retrieval stage rather than at utilization. We argue that, under current retrieval practices, improving retrieval quality yields larger gains than increasing write-time sophistication. Code is publicly available at https://github.com/boqiny/memory-probe.

Chubin Zhang, Jianan Wang, Zifeng Gao et al.

Generalist Vision-Language-Action models are currently hindered by the scarcity of robotic data compared to the abundance of human video demonstrations. Existing Latent Action Models attempt to leverage video data but often suffer from visual entanglement, capturing noise rather than manipulation skills. To address this, we propose Contrastive Latent Action Pretraining (CLAP), a framework that aligns the visual latent space from videos with a proprioceptive latent space from robot trajectories. By employing contrastive learning, CLAP maps video transitions onto a quantized, physically executable codebook. Building on this representation, we introduce a dual-formulation VLA framework offering both CLAP-NTP, an autoregressive model excelling at instruction following and object generalization, and CLAP-RF, a Rectified Flow-based policy designed for high-frequency, precise manipulation. Furthermore, we propose a Knowledge Matching (KM) regularization strategy to mitigate catastrophic forgetting during fine-tuning. Extensive experiments demonstrate that CLAP significantly outperforms strong baselines, enabling the effective transfer of skills from human videos to robotic execution. Project page: https://lin-shan.com/CLAP/.

Yue Su, Sijin Chen, Haixin Shi et al.

Leveraging future observation modeling to facilitate action generation presents a promising avenue for enhancing the capabilities of Vision-Language-Action (VLA) models. However, existing approaches struggle to strike a balance between maintaining efficient, predictable future representations and preserving sufficient fine-grained information to guide precise action generation. To address this limitation, we propose WoG (World Guidance), a framework that maps future observations into compact conditions by injecting them into the action inference pipeline. The VLA is then trained to simultaneously predict these compressed conditions alongside future actions, thereby achieving effective world modeling within the condition space for action inference. We demonstrate that modeling and predicting this condition space not only facilitates fine-grained action generation but also exhibits superior generalization capabilities. Moreover, it learns effectively from substantial human manipulation videos. Extensive experiments across both simulation and real-world environments validate that our method significantly outperforms existing methods based on future prediction. Project page is available at: https://selen-suyue.github.io/WoGNet/

Kunlun Zhu, Jiaxun Zhang, Ziheng Qi et al.

Recent advancements in large language model (LLM) agents have significantly accelerated scientific discovery automation, yet concurrently raised critical ethical and safety concerns. To systematically address these challenges, we introduce \textbf{SafeScientist}, an innovative AI scientist framework explicitly designed to enhance safety and ethical responsibility in AI-driven scientific exploration. SafeScientist proactively refuses ethically inappropriate or high-risk tasks and rigorously emphasizes safety throughout the research process. To achieve comprehensive safety oversight, we integrate multiple defensive mechanisms, including prompt monitoring, agent-collaboration monitoring, tool-use monitoring, and an ethical reviewer component. Complementing SafeScientist, we propose \textbf{SciSafetyBench}, a novel benchmark specifically designed to evaluate AI safety in scientific contexts, comprising 240 high-risk scientific tasks across 6 domains, alongside 30 specially designed scientific tools and 120 tool-related risk tasks. Extensive experiments demonstrate that SafeScientist significantly improves safety performance by 35\% compared to traditional AI scientist frameworks, without compromising scientific output quality. Additionally, we rigorously validate the robustness of our safety pipeline against diverse adversarial attack methods, further confirming the effectiveness of our integrated approach. The code and data will be available at https://github.com/ulab-uiuc/SafeScientist. \textcolor{red}{Warning: this paper contains example data that may be offensive or harmful.}

Kuan Zhang, Dongchen Liu, Qiyue Zhao et al.

The real world unfolds along a single set of physics laws, yet human intelligence demonstrates a remarkable capacity to generalize experiences from this singular physical existence into a multiverse of games, each governed by entirely different rules, aesthetics, physics, and objectives. This omni-reality adaptability is a hallmark of general intelligence. As Artificial Intelligence progresses towards Artificial General Intelligence, the multiverse of games has evolved from mere entertainment into the ultimate ground for training and evaluating AGI. The pursuit of this generality has unfolded across four eras: from environment-specific symbolic and reinforcement learning agents, to current large foundation models acting as generalist players, and toward a future creator stage where agent both creates new game worlds and continually evolves within them. We trace the full lifecycle of a generalist game player along four interdependent pillars: Dataset, Model, Harness, and Benchmark. Every advance across these pillars can be read as an attempt to break one of five fundamental trade-offs that currently bound the whole system. Building on this end-to-end view, we chart a five-level roadmap, progressing from single-game mastery to the ultimate creator stage in which the agent simultaneously creates and evolves within theoretical game multiverse. Taken together, our work offers a unified lens onto a rapidly shifting field,and a principled path toward the omnipotent generalist agent capable of seamlessly mastering any challenge within the multiverse of games, thereby paving the way for AGI.

Qingyu Meng, Min Chen, Dingming Liu et al.

Large language models (LLMs) can generate fluent dialogue, but prior works lack situational grounding, dynamic strategy control, and evaluation aligned with clinical standards in motivational interviewing (MI). We introduce StoryMI, a multi-LLM agent framework for controllable MI dialogue generation, where questionnaire-based client profiles are expanded into situational stories that provide narrative context for the dialogue. Therapist and client agents generate MI-coded utterances guided by MI codes selected by the interaction agent, while an interaction agent dynamically coordinates exchanges to control MI strategies during a multi-turn conversation. We propose a two-level evaluation protocol: lexical metrics and MI-specific measures of macro-level counseling strategies, alongside LLM-as-judge and human expert assessments. We construct a dataset of 6K simulated MI dialogues grounded in 1K questionnaire-story pairs, covering 12 MI codes and 13 symptom domains, and benchmark six open- and closed-source LLMs. Our results show that situational grounding and macro-level control can improve MI adherence and clinical plausibility, demonstrating the effectiveness of a structured multi-agent workflow for psychotherapy dialogue generation. We provide code and data for reproducibility.

Maximilian Schiffer, Heiko Hoppe, Yue Su et al.

Combinatorial optimization augmented machine learning (COAML) has recently emerged as a powerful paradigm for integrating predictive models with combinatorial decision-making. By embedding combinatorial optimization oracles into learning pipelines, COAML enables the construction of policies that are both data-driven and feasibility-preserving, bridging the traditions of machine learning, operations research, and stochastic optimization. This paper provides a comprehensive overview of the state of the art in COAML. We introduce a unifying framework for COAML pipelines, describe their methodological building blocks, and formalize their connection to empirical cost minimization. We then develop a taxonomy of problem settings based on the form of uncertainty and decision structure. Using this taxonomy, we review algorithmic approaches for static and dynamic problems, survey applications across domains such as scheduling, vehicle routing, stochastic programming, and reinforcement learning, and synthesize methodological contributions in terms of empirical cost minimization, imitation learning, and reinforcement learning. Finally, we identify key research frontiers. This survey aims to serve both as a tutorial introduction to the field and as a roadmap for future research at the interface of combinatorial optimization and machine learning.

Boqin Yuan, Renchu Song, Yue Su et al.

Skill-distillation pipelines learn reusable rules from LLM agent trajectories, but they lack a key signal: how much each step costs. Without per-step cost, a pipeline cannot distinguish adding a missing step to fix a bug from removing an expensive step that never affected the outcome. We introduce ClawTrace, an agent tracing platform that records every LLM call, tool use, and sub-agent spawn during an agent session and compiles each session into a TraceCard: a compact YAML summary with per-step USD cost, token counts, and redundancy flags. Built on ClawTrace, CostCraft is a distillation pipeline that reads TraceCards and produces three types of skill patches. Preserve patches keep behaviors that led to success. Prune patches remove expensive steps that did not matter, each backed by a counterfactual argument against a named high-cost step. Repair patches fix failures grounded in oracle evidence. Ablations on 30 held-out SpreadsheetBench tasks show that both cost attribution and prune patches independently reduce quality regressions. When the same skill is applied to 30 unrelated SkillsBench tasks, an unexpected asymmetry emerges: prune rules transferred across benchmarks and cut median cost by 32%, while preserve rules, trained on benchmark-specific conventions, caused regressions on new task types. We release ClawTrace and TraceCards as open infrastructure for cost-aware agent research.

Yue Su, Xinyu Zhan, Hongjie Fang et al.

Mainstream visuomotor policies predominantly rely on generative models for holistic action prediction, while current autoregressive policies, predicting the next token or chunk, have shown suboptimal results. This motivates a search for more effective learning methods to unleash the potential of autoregressive policies for robotic manipulation. This paper introduces a bidirectionally expanded learning approach, termed Dense Policy, to establish a new paradigm for autoregressive policies in action prediction. It employs a lightweight encoder-only architecture to iteratively unfold the action sequence from an initial single frame into the target sequence in a coarse-to-fine manner with logarithmic-time inference. Extensive experiments validate that our dense policy has superior autoregressive learning capabilities and can surpass existing holistic generative policies. Our policy, example data, and training code will be publicly available upon publication. Project page: https: //selen-suyue.github.io/DspNet/.

Mingke Xiao, Yue Su, Liang Yu et al.

The deployment of neural networks in vehicle platforms and wearable Artificial Intelligence-of-Things (AIOT) scenarios has become a research area that has attracted much attention. With the continuous evolution of deep learning technology, many image classification models are committed to improving recognition accuracy, but this is often accompanied by problems such as large model resource usage, complex structure, and high power consumption, which makes it challenging to deploy on resource-constrained platforms. Herein, we propose an ultra-lightweight binary neural network (BNN) model designed for hardware deployment, and conduct image classification research based on the German Traffic Sign Recognition Benchmark (GTSRB) dataset. In addition, we also verify it on the Chinese Traffic Sign (CTS) and Belgian Traffic Sign (BTS) datasets. The proposed model shows excellent recognition performance with an accuracy of up to 97.64%, making it one of the best performing BNN models in the GTSRB dataset. Compared with the full-precision model, the accuracy loss is controlled within 1%, and the parameter storage overhead of the model is only 10% of that of the full-precision model. More importantly, our network model only relies on logical operations and low-bit width fixed-point addition and subtraction operations during the inference phase, which greatly simplifies the design complexity of the processing element (PE). Our research shows the great potential of BNN in the hardware deployment of computer vision models, especially in the field of computer vision tasks related to autonomous driving.

Albert Tang, Yifan Mo, Jie Li et al.

The double empathy problem frames communication difficulties between neurodivergent and neurotypical individuals as arising from mutual misunderstanding, yet most interventions focus on autistic individuals. We present NeuroWise, a multi-agent LLM-based coaching system that supports neurotypical users through stress visualization, interpretation of internal experiences, and contextual guidance. In a between-subjects study (N=30), NeuroWise was rated as helpful by all participants and showed a significant condition-time effect on deficit-based attributions (p=0.02): NeuroWise users reduced deficit framing, while baseline users shifted toward blaming autistic "deficits" after difficult interactions. NeuroWise users also completed conversations more efficiently (37% fewer turns, p=0.03). These findings suggest that AI-based interpretation can support attributional change by helping users recognize communication challenges as mutual.

Srivathsan Badrinarayanan, Yue Su, Janghoon Ock et al.

Protein mutations can have profound effects on biological function, making accurate prediction of property changes critical for drug discovery, protein engineering, and precision medicine. Current approaches rely on fine-tuning protein-specific transformers for individual datasets, but struggle with cross-dataset generalization due to heterogeneous experimental conditions and limited target domain data. We introduce two key innovations: (1) the first application of Model-Agnostic Meta-Learning (MAML) to protein mutation property prediction, and (2) a novel mutation encoding strategy using separator tokens to directly incorporate mutations into sequence context. We build upon transformer architectures integrating them with MAML to enable rapid adaptation to new tasks through minimal gradient steps rather than learning dataset-specific patterns. Our mutation encoding addresses the critical limitation where standard transformers treat mutation positions as unknown tokens, significantly degrading performance. Evaluation across three diverse protein mutation datasets (functional fitness, thermal stability, and solubility) demonstrates significant advantages over traditional fine-tuning. In cross-task evaluation, our meta-learning approach achieves 29% better accuracy for functional fitness with 65% less training time, and 94% better accuracy for solubility with 55% faster training. The framework maintains consistent training efficiency regardless of dataset size, making it particularly valuable for industrial applications and early-stage protein design where experimental data is limited. This work establishes a systematic application of meta-learning to protein mutation analysis and introduces an effective mutation encoding strategy, offering transformative methodology for cross-domain generalization in protein engineering.

Yue Su, Hao Li, Maoguo Gong

Visible-infrared pedestrian Re-identification (VI-ReID) aims to match pedestrian images captured by infrared cameras and visible cameras. However, VI-ReID, like other traditional cross-modal image matching tasks, poses significant challenges due to its human-centered nature. This is evidenced by the shortcomings of existing methods, which struggle to extract common features across modalities, while losing valuable information when bridging the gap between them in the implicit feature space, potentially compromising security. To address this vulnerability, this paper introduces the first physical adversarial attack against VI-ReID models. Our method, termed Edge-Attack, specifically tests the models' ability to leverage deep-level implicit features by focusing on edge information, the most salient explicit feature differentiating individuals across modalities. Edge-Attack utilizes a novel two-step approach. First, a multi-level edge feature extractor is trained in a self-supervised manner to capture discriminative edge representations for each individual. Second, a generative model based on Vision Transformer Generative Adversarial Networks (ViTGAN) is employed to generate adversarial patches conditioned on the extracted edge features. By applying these patches to pedestrian clothing, we create realistic, physically-realizable adversarial samples. This black-box, self-supervised approach ensures the generalizability of our attack against various VI-ReID models. Extensive experiments on SYSU-MM01 and RegDB datasets, including real-world deployments, demonstrate the effectiveness of Edge- Attack in significantly degrading the performance of state-of-the-art VI-ReID methods.