MedProbeBench: Systematic Benchmarking at Deep Evidence Integration for Expert-level Medical GuidelineJiyao Liu, Jianghan Shen, Sida Song et al.
Recent advances in deep research systems enable large language models to retrieve, synthesize, and reason over large-scale external knowledge. In medicine, developing clinical guidelines critically depends on such deep evidence integration. However, existing benchmarks fail to evaluate this capability in realistic workflows requiring multi-step evidence integration and expert-level judgment. To address this gap, we introduce MedProbeBench, the first benchmark leveraging high-quality clinical guidelines as expert-level references. Medical guidelines, with their rigorous standards in neutrality and verifiability, represent the pinnacle of medical expertise and pose substantial challenges for deep research agents. For evaluation, we propose MedProbe-Eval, a comprehensive evaluation framework featuring: (1) Holistic Rubrics with 1,200+ task-adaptive rubric criteria for comprehensive quality assessment, and (2) Fine-grained Evidence Verification for rigorous validation of evidence precision, grounded in 5,130+ atomic claims. Evaluation of 17 LLMs and deep research agents reveals critical gaps in evidence integration and guideline generation, underscoring the substantial distance between current capabilities and expert-level clinical guideline development. Project: https://github.com/uni-medical/MedProbeBench
CuSearch: Curriculum Rollout Sampling via Search Depth for Agentic RAGJianghan Shen, Siqi Luo, Xinyu Cheng et al.
Reinforcement Learning with Verifiable Rewards (RLVR) has emerged as a promising paradigm for training agentic retrieval-augmented generation (RAG) systems from outcome-only supervision. Most existing methods optimize policies from uniformly sampled rollouts, implicitly treating all trajectories as equally informative. However, trajectories differ substantially in search depth and are therefore not equally informative: deeper-search trajectories contain more retrieval decision points and provide denser direct supervision for the retrieval sub-policy. Moreover, this heterogeneity grows over training as the within-batch depth distribution shifts toward higher values, yet uniform rollout sampling remains blind to this shift. To address this, we propose CuSearch, a curriculum rollout sampling framework built on Search-Depth Greedy Allocation (SDGA), a batch-level operator that reallocates a fixed update budget toward deeper-search trajectories. SDGA-Auto always targets the deepest available trajectories in the current batch, yielding an implicit training-aligned curriculum as the depth distribution shifts upward. SDGA-Phase explicitly advances the curriculum threshold as deeper trajectories become sufficiently abundant. Experiments across model types and retrieval frameworks show that CuSearch consistently improves performance, achieving up to 11.8 exact-match points over standard GRPO on ZeroSearch. These results establish per-trajectory search depth as a reliable, annotation-free proxy for retrieval supervision density in RLVR-based agentic RAG training. The code is available at https://github.com/MrToser/CuSearch.
23.5AIMay 16
Sketch Then Paint: Hierarchical Reinforcement Learning for Diffusion Multi-Modal Large Language ModelsSiqi Luo, Jianghan Shen, Yi Xin et al.
Diffusion Multi-Modal Large Language Models (dMLLMs) are powerful for image generation, but optimizing them through reinforcement learning (RL) remains a major challenge. One primary difficulty is that a single image can be generated through many different unmasking sequences, which makes calculating importance ratios often intractable. Additionally, existing methods tend to ignore the hierarchical generation process of dMLLMs, where early tokens define the global layout and later tokens focus on local details. By assigning uniform rewards to all tokens, these current methods fail to reflect the actual contribution of each token to the final image. To address these issues, we propose Hierarchical Token GRPO (HT-GRPO), which integrates this hierarchy directly into the policy optimization process. Our approach features a Sketch-Then-Paint training scheme that organizes updates into three distinct stages: global, structure, and refinement. We also use a prompt-conditioned estimator to calculate importance ratios starting from a fully masked state. Furthermore, we introduce a Hierarchical Credit Assignment mechanism that prioritizes key structural tokens to ensure accurate reward propagation. Experiments using two popular dMLLM backbones, MMaDA and Lumina-DiMOO, demonstrate that HT-GRPO achieves substantial gains on the GenEval and DPG benchmarks. Evaluations across six additional metrics confirm significant improvements in image quality, aesthetics, and human preference.
26.9AIJun 15
A First-Principles Derivation of LLM Policy Optimization: From Expected Reward to GRPO and Its Structural ExtensionsJianghan Shen, Siqi Luo, Yue Li et al.
Policy gradient algorithms for language models optimize the same objective $J(θ) = \mathbb{E}*{τ\sim p*θ(τ)}[R(τ)]$, which has exactly two factors: the trajectory probability $p_θ(τ)$ and the reward $R(τ)$. Every method from REINFORCE to PPO to GRPO and their descendants modifies one or both factors to address a specific failure in the preceding formulation. Existing surveys organize these methods by domain or chronology, which obscures the rationale behind each design choice and the precise location of its intervention within the gradient estimator. This survey revisits the landscape of LLM policy optimization from $J(θ)$ on first principles and uses the trajectory side, induced by $p_θ(τ)$, and the reward side, induced by $R(τ)$, as the two axes along which methods are located. It covers the path from REINFORCE and PPO to GRPO, as well as post-GRPO variants, Agentic RL, and GRPO-OPD. The resulting framework is unified, diagnostic, and extensible: it analyzes methods from a shared objective, identifies which side each method modifies and why, and applies the same trajectory and reward axes across these settings. Across these settings, the framework also exposes compound failures that no single-side fix resolves and that therefore require joint design of the trajectory side and the reward side. The boundary cases and coupled failures identified by this map mark where existing solutions run out and provide a principled starting point for designing the next generation of LLM policy optimization algorithms.
21.1CVMar 8
MedQ-Deg: A Multidimensional Benchmark for Evaluating MLLMs Across Medical Image Quality DegradationsJiyao Liu, Junzhi Ning, Chenglong Ma et al.
Despite impressive performance on standard benchmarks, multimodal large language models (MLLMs) face critical challenges in real-world clinical environments where medical images inevitably suffer various quality degradations. Existing benchmarks exhibit two key limitations: (1) absence of large-scale, multidimensional assessment across medical image quality gradients and (2) no systematic confidence calibration analysis. To address these gaps, we present MedQ-Deg, a comprehensive benchmark for evaluating medical MLLMs under image quality degradations. MedQ-Deg provides multi-dimensional evaluation spanning 18 distinct degradation types, 30 fine-grained capability dimensions, and 7 imaging modalities, with 24,894 question-answer pairs. Each degradation is implemented at 3 severity degrees, calibrated by expert radiologists. We further introduce Calibration Shift metric, which quantifies the gap between a model's perceived confidence and actual performance to assess metacognitive reliability under degradation. Our comprehensive evaluation of 40 mainstream MLLMs reveals several critical findings: (1) overall model performance degrades systematically as degradation severity increases, (2) models universally exhibit the AI Dunning-Kruger Effect, maintaining inappropriately high confidence despite severe accuracy collapse, and (3) models display markedly differentiated behavioral patterns across capability dimensions, imaging modalities, and degradation types. We hope MedQ-Deg drives progress toward medical MLLMs that are robust and trustworthy in real clinical practice.