Zhaoxiang Ye

Sunyi Zheng, Xiaonan Cui, Yuxuan Sun et al.

Accurate image classification and retrieval are of importance for clinical diagnosis and treatment decision-making. The recent contrastive language-image pretraining (CLIP) model has shown remarkable proficiency in understanding natural images. Drawing inspiration from CLIP, PathCLIP is specifically designed for pathology image analysis, utilizing over 200,000 image and text pairs in training. While the performance the PathCLIP is impressive, its robustness under a wide range of image corruptions remains unknown. Therefore, we conduct an extensive evaluation to analyze the performance of PathCLIP on various corrupted images from the datasets of Osteosarcoma and WSSS4LUAD. In our experiments, we introduce seven corruption types including brightness, contrast, Gaussian blur, resolution, saturation, hue, and markup at four severity levels. Through experiments, we find that PathCLIP is relatively robustness to image corruptions and surpasses OpenAI-CLIP and PLIP in zero-shot classification. Among the seven corruptions, blur and resolution can cause server performance degradation of the PathCLIP. This indicates that ensuring the quality of images is crucial before conducting a clinical test. Additionally, we assess the robustness of PathCLIP in the task of image-image retrieval, revealing that PathCLIP performs less effectively than PLIP on Osteosarcoma but performs better on WSSS4LUAD under diverse corruptions. Overall, PathCLIP presents impressive zero-shot classification and retrieval performance for pathology images, but appropriate care needs to be taken when using it. We hope this study provides a qualitative impression of PathCLIP and helps understand its differences from other CLIP models.

Zaijun Ye, Chen-Song Zhang, Wansheng Wang

Neural operators have emerged as powerful tools for learning solution operators of partial differential equations. However, in time-dependent problems, standard training strategies such as teacher forcing introduce a mismatch between training and inference, leading to compounding errors in long-term autoregressive predictions. To address this issue, we propose Recurrent Neural Operators (RNOs)-a novel framework that integrates recurrent training into neural operator architectures. Instead of conditioning each training step on ground-truth inputs, RNOs recursively apply the operator to their own predictions over a temporal window, effectively simulating inference-time dynamics during training. This alignment mitigates exposure bias and enhances robustness to error accumulation. Theoretically, we show that recurrent training can reduce the worst-case exponential error growth typical of teacher forcing to linear growth. Empirically, we demonstrate that recurrently trained Multigrid Neural Operators significantly outperform their teacher-forced counterparts in long-term accuracy and stability on standard benchmarks. Our results underscore the importance of aligning training with inference dynamics for robust temporal generalization in neural operator learning.

Lu Xu, Yuwei Zhang, Ying Liu et al.

Low-dose CT has been a key diagnostic imaging modality to reduce the potential risk of radiation overdose to patient health. Despite recent advances, CNN-based approaches typically apply filters in a spatially invariant way and adopt similar pixel-level losses, which treat all regions of the CT image equally and can be inefficient when fine-grained structures coexist with non-uniformly distributed noises. To address this issue, we propose a Structure-preserving Kernel Prediction Network (StructKPN) that combines the kernel prediction network with a structure-aware loss function that utilizes the pixel gradient statistics and guides the model towards spatially-variant filters that enhance noise removal, prevent over-smoothing and preserve detailed structures for different regions in CT imaging. Extensive experiments demonstrated that our approach achieved superior performance on both synthetic and non-synthetic datasets, and better preserves structures that are highly desired in clinical screening and low-dose protocol optimization.