Massimiliano Del Bene

Yin Lin, Domenico Aquino, Alberto Redaelli et al.

Touchless interaction with medical images is becoming increasingly important in the surgical field, where sterility and continuity of the operational workflow are essential requirements. This work presents a vision-based system for intraoperative navigation of medical images through hand gestures acquired using a single RGB camera. Unlike many existing solutions, the system does not require additional hardware or user-specific training. Hand tracking is performed in real time using MediaPipe Hands, which provides a 2.5D estimation of hand landmarks. Simple and intuitive gestures are then mapped into translation, rotation, and zoom commands, enabling continuous and natural interaction with the image viewer. The system architecture is independent from the visualization software and, for implementation simplicity, in this study it was integrated with PyVista. Performance was evaluated through frame-level logging and quantitative analysis of latency, stability, and interaction robustness metrics. Experimental results highlight real-time behavior, with reduced latencies and stable control, in line with the requirements of fluid interaction. The system demonstrates the feasibility of a low-cost touchless solution for intraoperative access to medical images, laying the groundwork for future clinical evaluations.

Santiago Cepeda, Olga Esteban-Sinovas, Roberto Romero et al.

Intraoperative ultrasound (ioUS) is a valuable tool in brain tumor surgery due to its versatility, affordability, and seamless integration into the surgical workflow. However, its adoption remains limited, primarily because of the challenges associated with image interpretation and the steep learning curve required for effective use. This study aimed to enhance the interpretability of ioUS images by developing a real-time brain tumor detection system deployable in the operating room. We collected 2D ioUS images from the Brain Tumor Intraoperative Database (BraTioUS) and the public ReMIND dataset, annotated with expert-refined tumor labels. Using the YOLO11 architecture and its variants, we trained object detection models to identify brain tumors. The dataset included 1,732 images from 192 patients, divided into training, validation, and test sets. Data augmentation expanded the training set to 11,570 images. In the test dataset, YOLO11s achieved the best balance of precision and computational efficiency, with a mAP@50 of 0.95, mAP@50-95 of 0.65, and a processing speed of 34.16 frames per second. The proposed solution was prospectively validated in a cohort of 15 consecutively operated patients diagnosed with brain tumors. Neurosurgeons confirmed its seamless integration into the surgical workflow, with real-time predictions accurately delineating tumor regions. These findings highlight the potential of real-time object detection algorithms to enhance ioUS-guided brain tumor surgery, addressing key challenges in interpretation and providing a foundation for future development of computer vision-based tools for neuro-oncological surgery.