Eric Sun

Rong Ma, Eric D. Sun, David Donoho et al.

Single-cell data integration can provide a comprehensive molecular view of cells, and many algorithms have been developed to remove unwanted technical or biological variations and integrate heterogeneous single-cell datasets. Despite their wide usage, existing methods suffer from several fundamental limitations. In particular, we lack a rigorous statistical test for whether two high-dimensional single-cell datasets are alignable (and therefore should even be aligned). Moreover, popular methods can substantially distort the data during alignment, making the aligned data and downstream analysis difficult to interpret. To overcome these limitations, we present a spectral manifold alignment and inference (SMAI) framework, which enables principled and interpretable alignability testing and structure-preserving integration of single-cell data with the same type of features. SMAI provides a statistical test to robustly assess the alignability between datasets to avoid misleading inference, and is justified by high-dimensional statistical theory. On a diverse range of real and simulated benchmark datasets, it outperforms commonly used alignment methods. Moreover, we show that SMAI improves various downstream analyses such as identification of differentially expressed genes and imputation of single-cell spatial transcriptomics, providing further biological insights. SMAI's interpretability also enables quantification and a deeper understanding of the sources of technical confounders in single-cell data.

Rong Ma, Eric D. Sun, James Zou

Dimension reduction and data visualization aim to project a high-dimensional dataset to a low-dimensional space while capturing the intrinsic structures in the data. It is an indispensable part of modern data science, and many dimensional reduction and visualization algorithms have been developed. However, different algorithms have their own strengths and weaknesses, making it critically important to evaluate their relative performance for a given dataset, and to leverage and combine their individual strengths. In this paper, we propose an efficient spectral method for assessing and combining multiple visualizations of a given dataset produced by diverse algorithms. The proposed method provides a quantitative measure -- the visualization eigenscore -- of the relative performance of the visualizations for preserving the structure around each data point. Then it leverages the eigenscores to obtain a consensus visualization, which has much improved { quality over the individual visualizations in capturing the underlying true data structure.} Our approach is flexible and works as a wrapper around any visualizations. We analyze multiple simulated and real-world datasets from diverse applications to demonstrate the effectiveness of the eigenscores for evaluating visualizations and the superiority of the proposed consensus visualization. Furthermore, we establish rigorous theoretical justification of our method based on a general statistical framework, yielding fundamental principles behind the empirical success of consensus visualization along with practical guidance.

Sunit Sivasankaran, Eric Sun, Jinyu Li et al.

Obtaining word timestamp information from end-to-end (E2E) ASR models remains challenging due to the lack of explicit time alignment during training. This issue is further complicated in multilingual models. Existing methods, either rely on lexicons or introduce additional tokens, leading to scalability issues and increased computational costs. In this work, we propose a new approach to estimate word boundaries without relying on lexicons. Our method leverages word embeddings from sub-word token units and a pretrained ASR model, requiring only word alignment information during training. Our proposed method can scale-up to any number of languages without incurring any additional cost. We validate our approach using a multilingual ASR model trained on five languages and demonstrate its effectiveness against a strong baseline.

Kenichi Kumatani, Robert Gmyr, Felipe Cruz Salinas et al.

The sparsely-gated Mixture of Experts (MoE) can magnify a network capacity with a little computational complexity. In this work, we investigate how multi-lingual Automatic Speech Recognition (ASR) networks can be scaled up with a simple routing algorithm in order to achieve better accuracy. More specifically, we apply the sparsely-gated MoE technique to two types of networks: Sequence-to-Sequence Transformer (S2S-T) and Transformer Transducer (T-T). We demonstrate through a set of ASR experiments on multiple language data that the MoE networks can reduce the relative word error rates by 16.3% and 4.6% with the S2S-T and T-T, respectively. Moreover, we thoroughly investigate the effect of the MoE on the T-T architecture in various conditions: streaming mode, non-streaming mode, the use of language ID and the label decoder with the MoE.

Rimita Lahiri, Kenichi Kumatani, Eric Sun et al.

Multilingual end-to-end(E2E) models have shown a great potential in the expansion of the language coverage in the realm of automatic speech recognition(ASR). In this paper, we aim to enhance the multilingual ASR performance in two ways, 1)studying the impact of feeding a one-hot vector identifying the language, 2)formulating the task with a meta-learning objective combined with self-supervised learning (SSL). We associate every language with a distinct task manifold and attempt to improve the performance by transferring knowledge across learning processes itself as compared to transferring through final model parameters. We employ this strategy on a dataset comprising of 6 languages for an in-domain ASR task, by minimizing an objective related to expected gradient path length. Experimental results reveal the best pre-training strategy resulting in 3.55% relative reduction in overall WER. A combination of LEAP and SSL yields 3.51% relative reduction in overall WER when using language ID.

Zhong Meng, Yu Wu, Naoyuki Kanda et al.

Integrating external language models (LMs) into end-to-end (E2E) models remains a challenging task for domain-adaptive speech recognition. Recently, internal language model estimation (ILME)-based LM fusion has shown significant word error rate (WER) reduction from Shallow Fusion by subtracting a weighted internal LM score from an interpolation of E2E model and external LM scores during beam search. However, on different test sets, the optimal LM interpolation weights vary over a wide range and have to be tuned extensively on well-matched validation sets. In this work, we perform LM fusion in the minimum WER (MWER) training of an E2E model to obviate the need for LM weights tuning during inference. Besides MWER training with Shallow Fusion (MWER-SF), we propose a novel MWER training with ILME (MWER-ILME) where the ILME-based fusion is conducted to generate N-best hypotheses and their posteriors. Additional gradient is induced when internal LM is engaged in MWER-ILME loss computation. During inference, LM weights pre-determined in MWER training enable robust LM integrations on test sets from different domains. Experimented with 30K-hour trained transformer transducers, MWER-ILME achieves on average 8.8% and 5.8% relative WER reductions from MWER and MWER-SF training, respectively, on 6 different test sets

Zhong Meng, Naoyuki Kanda, Yashesh Gaur et al.

The efficacy of external language model (LM) integration with existing end-to-end (E2E) automatic speech recognition (ASR) systems can be improved significantly using the internal language model estimation (ILME) method. In this method, the internal LM score is subtracted from the score obtained by interpolating the E2E score with the external LM score, during inference. To improve the ILME-based inference, we propose an internal LM training (ILMT) method to minimize an additional internal LM loss by updating only the E2E model components that affect the internal LM estimation. ILMT encourages the E2E model to form a standalone LM inside its existing components, without sacrificing ASR accuracy. After ILMT, the more modular E2E model with matched training and inference criteria enables a more thorough elimination of the source-domain internal LM, and therefore leads to a more effective integration of the target-domain external LM. Experimented with 30K-hour trained recurrent neural network transducer and attention-based encoder-decoder models, ILMT with ILME-based inference achieves up to 31.5% and 11.4% relative word error rate reductions from standard E2E training with Shallow Fusion on out-of-domain LibriSpeech and in-domain Microsoft production test sets, respectively.

Zhong Meng, Sarangarajan Parthasarathy, Eric Sun et al.

The external language models (LM) integration remains a challenging task for end-to-end (E2E) automatic speech recognition (ASR) which has no clear division between acoustic and language models. In this work, we propose an internal LM estimation (ILME) method to facilitate a more effective integration of the external LM with all pre-existing E2E models with no additional model training, including the most popular recurrent neural network transducer (RNN-T) and attention-based encoder-decoder (AED) models. Trained with audio-transcript pairs, an E2E model implicitly learns an internal LM that characterizes the training data in the source domain. With ILME, the internal LM scores of an E2E model are estimated and subtracted from the log-linear interpolation between the scores of the E2E model and the external LM. The internal LM scores are approximated as the output of an E2E model when eliminating its acoustic components. ILME can alleviate the domain mismatch between training and testing, or improve the multi-domain E2E ASR. Experimented with 30K-hour trained RNN-T and AED models, ILME achieves up to 15.5% and 6.8% relative word error rate reductions from Shallow Fusion on out-of-domain LibriSpeech and in-domain Microsoft production test sets, respectively.

Jinyu Li, Rui Zhao, Eric Sun et al.

While the community keeps promoting end-to-end models over conventional hybrid models, which usually are long short-term memory (LSTM) models trained with a cross entropy criterion followed by a sequence discriminative training criterion, we argue that such conventional hybrid models can still be significantly improved. In this paper, we detail our recent efforts to improve conventional hybrid LSTM acoustic models for high-accuracy and low-latency automatic speech recognition. To achieve high accuracy, we use a contextual layer trajectory LSTM (cltLSTM), which decouples the temporal modeling and target classification tasks, and incorporates future context frames to get more information for accurate acoustic modeling. We further improve the training strategy with sequence-level teacher-student learning. To obtain low latency, we design a two-head cltLSTM, in which one head has zero latency and the other head has a small latency, compared to an LSTM. When trained with Microsoft's 65 thousand hours of anonymized training data and evaluated with test sets with 1.8 million words, the proposed two-head cltLSTM model with the proposed training strategy yields a 28.2\% relative WER reduction over the conventional LSTM acoustic model, with a similar perceived latency.

Liang Lu, Eric Sun, Yifan Gong

We propose self-teaching networks to improve the generalization capacity of deep neural networks. The idea is to generate soft supervision labels using the output layer for training the lower layers of the network. During the network training, we seek an auxiliary loss that drives the lower layer to mimic the behavior of the output layer. The connection between the two network layers through the auxiliary loss can help the gradient flow, which works similar to the residual networks. Furthermore, the auxiliary loss also works as a regularizer, which improves the generalization capacity of the network. We evaluated the self-teaching network with deep recurrent neural networks on speech recognition tasks, where we trained the acoustic model using 30 thousand hours of data. We tested the acoustic model using data collected from 4 scenarios. We show that the self-teaching network can achieve consistent improvements and outperform existing methods such as label smoothing and confidence penalization.

Eric D. Sun, Ron Dekel

Deep neural network (DNN) models for computer vision are now capable of human-level object recognition. Consequently, similarities in the performance and vulnerabilities of DNN and human vision are of great interest. Here we characterize the response of the VGG-19 DNN to images of the Scintillating Grid visual illusion, in which white dots are perceived to be partially black. We observed a significant deviation from the expected monotonic relation between VGG-19 representational dissimilarity and dot whiteness in the Scintillating Grid. That is, a linear increase in dot whiteness leads to a non-linear increase and then, remarkably, a decrease (non-monotonicity) in representational dissimilarity. In control images, mostly monotonic relations between representational dissimilarity and dot whiteness were observed. Furthermore, the dot whiteness level corresponding to the maximal representational dissimilarity (i.e. onset of non-monotonic dissimilarity) matched closely with that corresponding to the onset of illusion perception in human observers. As such, the non-monotonic response in the DNN is a potential model correlate for human illusion perception.