Jie Xing

Yuxi Lin, Yongkang Li, Jie Xing et al.

Among the diverse services provided by Location-Based Social Networks (LBSNs), Next Point-of-Interest (POI) recommendation plays a crucial role in inferring user preferences from historical check-in trajectories. However, existing sequential and graph-based methods frequently neglect significant mobility variations across distinct contextual scenarios (e.g., tourists versus locals). This oversight results in suboptimal performance due to two fundamental limitations: the inability to capture scenario-specific features and the failure to resolve inherent inter-scenario conflicts. To overcome these limitations, we propose the Multifaceted Scenario-Aware Hypergraph Learning method (MSAHG), a framework that adopts a scenario-splitting paradigm for next POI recommendation. Our main contributions are: (1) Construction of scenario-specific, multi-view disentangled sub-hypergraphs to capture distinct mobility patterns; (2) A parameter-splitting mechanism to adaptively resolve conflicting optimization directions across scenarios while preserving generalization capability. Extensive experiments on three real-world datasets demonstrate that MSAHG consistently outperforms five state-of-the-art methods across diverse scenarios, confirming its effectiveness in multi-scenario POI recommendation.

Siqi Fan, Yuguang Xie, Bowen Cai et al.

Understanding the chemical structure from a graphical representation of a molecule is a challenging image caption task that would greatly benefit molecule-centric scientific discovery. Variations in molecular images and caption subtasks pose a significant challenge in both image representation learning and task modeling. Yet, existing methods only focus on a specific caption task that translates a molecular image into its graph structure, i.e., OCSR. In this paper, we propose the Optical Chemical Structure Understanding (OCSU) task, which extends low-level recognition to multilevel understanding and aims to translate chemical structure diagrams into readable strings for both machine and chemist. To facilitate the development of OCSU technology, we explore both OCSR-based and OCSR-free paradigms. We propose DoubleCheck to enhance OCSR performance via attentive feature enhancement for local ambiguous atoms. It can be cascaded with existing SMILES-based molecule understanding methods to achieve OCSU. Meanwhile, Mol-VL is a vision-language model end-to-end optimized for OCSU. We also construct Vis-CheBI20, the first large-scale OCSU dataset. Through comprehensive experiments, we demonstrate the proposed approaches excel at providing chemist-readable caption for chemical structure diagrams, which provide solid baselines for further research. Our code, model, and data are open-sourced at https://github.com/PharMolix/OCSU.

Jie Xing, Zheren Li, Biyuan Wang et al.

Breast cancer is the most common invasive cancer with the highest cancer occurrence in females. Handheld ultrasound is one of the most efficient ways to identify and diagnose the breast cancer. The area and the shape information of a lesion is very helpful for clinicians to make diagnostic decisions. In this study we propose a new deep-learning scheme, semi-pixel-wise cycle generative adversarial net (SPCGAN) for segmenting the lesion in 2D ultrasound. The method takes the advantage of a fully convolutional neural network (FCN) and a generative adversarial net to segment a lesion by using prior knowledge. We compared the proposed method to a fully connected neural network and the level set segmentation method on a test dataset consisting of 32 malignant lesions and 109 benign lesions. Our proposed method achieved a Dice similarity coefficient (DSC) of 0.92 while FCN and the level set achieved 0.90 and 0.79 respectively. Particularly, for malignant lesions, our method increases the DSC (0.90) of the fully connected neural network to 0.93 significantly (p$<$0.001). The results show that our SPCGAN can obtain robust segmentation results. The framework of SPCGAN is particularly effective when sufficient training samples are not available compared to FCN. Our proposed method may be used to relieve the radiologists' burden for annotation.