Chao Zhou

Wenqi Ji, Fang liu, Xinxin Du et al.

Interpersonal relationship quality is pivotal in social and occupational contexts. Existing analysis of interpersonal relationships mostly rely on subjective self-reports, whereas objective quantification remains challenging. In this paper, we propose a novel social relationship analysis framework using spatio-temporal patterns derived from dyadic EEG signals, which can be applied to quantitatively measure team cooperation in corporate team building, and evaluate interpersonal dynamics between therapists and patients in psychiatric therapy. First, we constructed a dyadic-EEG dataset from 72 pairs of participants with two relationships (stranger or friend) when watching emotional videos simultaneously. Then we proposed a deep neural network on dyadic-subject EEG signals, in which we combine the dynamic graph convolutional neural network for characterizing the interpersonal relationships among the EEG channels and 1-dimension convolution for extracting the information from the time sequence. To obtain the feature vectors from two EEG recordings that well represent the relationship of two subjects, we integrate deep canonical correlation analysis and triplet loss for training the network. Experimental results show that the social relationship type (stranger or friend) between two individuals can be effectively identified through their EEG data.

Yutao Ma, Tao Xu, Xiaolei Huang et al.

Objective: Ultrahigh-resolution optical coherence microscopy (OCM) has recently demonstrated its potential for accurate diagnosis of human cervical diseases. One major challenge for clinical adoption, however, is the steep learning curve clinicians need to overcome to interpret OCM images. Developing an intelligent technique for computer-aided diagnosis (CADx) to accurately interpret OCM images will facilitate clinical adoption of the technology and improve patient care. Methods: 497 high-resolution 3-D OCM volumes (600 cross-sectional images each) were collected from 159 ex vivo specimens of 92 female patients. OCM image features were extracted using a convolutional neural network (CNN) model, concatenated with patient information (e.g., age, HPV results), and classified using a support vector machine classifier. Ten-fold cross-validations were utilized to test the performance of the CADx method in a five-class classification task and a binary classification task. Results: An 88.3 plus or minus 4.9% classification accuracy was achieved for five fine-grained classes of cervical tissue, namely normal, ectropion, low-grade and high-grade squamous intraepithelial lesions (LSIL and HSIL), and cancer. In the binary classification task (low-risk [normal, ectropion and LSIL] vs. high-risk [HSIL and cancer]), the CADx method achieved an area-under-the-curve (AUC) value of 0.959 with an 86.7 plus or minus 11.4% sensitivity and 93.5 plus or minus 3.8% specificity. Conclusion: The proposed deep-learning based CADx method outperformed three human experts. It was also able to identify morphological characteristics in OCM images that were consistent with histopathological interpretations. Significance: Label-free OCM imaging, combined with deep-learning based CADx methods, hold a great promise to be used in clinical settings for the effective screening and diagnosis of cervical diseases.

Lian Duan, Xi Qin, Yuanhao He et al.

Convolutional neural networks are powerful tools for image segmentation and classification. Here, we use this method to identify and mark the heart region of Drosophila at different developmental stages in the cross-sectional images acquired by a custom optical coherence microscopy (OCM) system. With our well-trained convolutional neural network model, the heart regions through multiple heartbeat cycles can be marked with an intersection over union (IOU) of ~86%. Various morphological and dynamical cardiac parameters can be quantified accurately with automatically segmented heart regions. This study demonstrates an efficient heart segmentation method to analyze OCM images of the beating heart in Drosophila.