Changwei Song

Changwei Song, Qing Zhao, Jianqiang Li et al.

Psychological support hotlines are an effective suicide prevention measure that typically relies on professionals using suicide risk assessment scales to predict individual risk scores. However, the accuracy of scale-based predictive methods for suicide risk assessment can vary widely depending on the expertise of the operator. This limitation underscores the need for more reliable methods, prompting this research's innovative exploration of the use of artificial intelligence to improve the accuracy and efficiency of suicide risk prediction within the context of psychological support hotlines. The study included data from 1,549 subjects from 2015-2017 in China who contacted a psychological support hotline. Each participant was followed for 12 months to identify instances of suicidal behavior. We proposed a novel multi-task learning method that uses the large-scale pre-trained model Whisper for feature extraction and fits psychological scales while predicting the risk of suicide. The proposed method yields a 2.4\% points improvement in F1-score compared to the traditional manual approach based on the psychological scales. Our model demonstrated superior performance compared to the other eight popular models. To our knowledge, this study is the first to apply deep learning to long-term speech data to predict suicide risk in China, indicating grate potential for clinical applications. The source code is publicly available at: \url{https://github.com/songchangwei/Suicide-Risk-Prediction}.

Xin Yue, Xiaoling Liu, Qing Zhao et al.

Ultrasound imaging plays a critical role in the early detection of breast cancer. Accurate identification and segmentation of lesions are essential steps in clinical practice, requiring methods to assist physicians in lesion segmentation. However, ultrasound lesion segmentation models based on supervised learning require extensive manual labeling, which is both time-consuming and labor-intensive. In this study, we present a novel framework for weakly supervised lesion segmentation in early breast ultrasound images. Our method uses morphological enhancement and class activation map (CAM)-guided localization. Finally, we employ the Segment Anything Model (SAM), a computer vision foundation model, for detailed segmentation. This approach does not require pixel-level annotation, thereby reducing the cost of data annotation. The performance of our method is comparable to supervised learning methods that require manual annotations, achieving a Dice score of 74.39% and outperforming comparative supervised models in terms of Hausdorff distance in the BUSI dataset. These results demonstrate that our framework effectively integrates weakly supervised learning with SAM, providing a promising solution for breast cancer image analysis. The code for this study is available at: https://github.com/YueXin18/MorSeg-CAM-SAM.

Guanghui Fu, Qing Zhao, Jianqiang Li et al.

In the contemporary landscape of social media, an alarming number of users express negative emotions, some of which manifest as strong suicidal intentions. This situation underscores a profound need for trained psychological counselors who can enact effective mental interventions. However, the development of these professionals is often an imperative but time-consuming task. Consequently, the mobilization of non-professionals or volunteers in this capacity emerges as a pressing concern. Leveraging the capabilities of artificial intelligence, and in particular, the recent advances in large language models, offers a viable solution to this challenge. This paper introduces a novel model constructed on the foundation of large language models to fully assist non-professionals in providing psychological interventions on online user discourses. This framework makes it plausible to harness the power of non-professional counselors in a meaningful way. A comprehensive study was conducted involving ten professional psychological counselors of varying expertise, evaluating the system across five critical dimensions. The findings affirm that our system is capable of analyzing patients' issues with relative accuracy and proffering professional-level strategies recommendations, thereby enhancing support for non-professionals. This research serves as a compelling validation of the application of large language models in the field of psychology and lays the groundwork for a new paradigm of community-based mental health support.

Hongzhi Qi, Qing Zhao, Jianqiang Li et al.

On social media, users often express their personal feelings, which may exhibit cognitive distortions or even suicidal tendencies on certain specific topics. Early recognition of these signs is critical for effective psychological intervention. In this paper, we introduce two novel datasets from Chinese social media: SOS-HL-1K for suicidal risk classification and SocialCD-3K for cognitive distortions detection. The SOS-HL-1K dataset contained 1,249 posts and SocialCD-3K dataset was a multi-label classification dataset that containing 3,407 posts. We propose a comprehensive evaluation using two supervised learning methods and eight large language models (LLMs) on the proposed datasets. From the prompt engineering perspective, we experimented with two types of prompt strategies, including four zero-shot and five few-shot strategies. We also evaluated the performance of the LLMs after fine-tuning on the proposed tasks. The experimental results show that there is still a huge gap between LLMs relying only on prompt engineering and supervised learning. In the suicide classification task, this gap is 6.95% points in F1-score, while in the cognitive distortion task, the gap is even more pronounced, reaching 31.53% points in F1-score. However, after fine-tuning, this difference is significantly reduced. In the suicide and cognitive distortion classification tasks, the gap decreases to 4.31% and 3.14%, respectively. This research highlights the potential of LLMs in psychological contexts, but supervised learning remains necessary for more challenging tasks. All datasets and code are made available.

Yining Chen, Jianqiang Li, Changwei Song et al.

Suicide is a pressing global issue, demanding urgent and effective preventive interventions. Among the various strategies in place, psychological support hotlines had proved as a potent intervention method. Approximately two million people in China attempt suicide annually, with many individuals making multiple attempts. Prompt identification and intervention for high-risk individuals are crucial to preventing tragedies. With the rapid advancement of artificial intelligence (AI), especially the development of large-scale language models (LLMs), new technological tools have been introduced to the field of mental health. This study included 1284 subjects, and was designed to validate whether deep learning models and LLMs, using audio and transcribed text from support hotlines, can effectively predict suicide risk. We proposed a simple LLM-based pipeline that first summarizes transcribed text from approximately one hour of speech to extract key features, and then predict suicidial bahaviours in the future. We compared our LLM-based method with the traditional manual scale approach in a clinical setting and with five advanced deep learning models. Surprisingly, the proposed simple LLM pipeline achieved strong performance on a test set of 46 subjects, with an F1 score of 76\% when combined with manual scale rating. This is 7\% higher than the best speech-based deep learning models and represents a 27.82\% point improvement in F1 score compared to using the manual scale apporach alone. Our study explores new applications of LLMs and demonstrates their potential for future use in suicide prevention efforts.

Yuning Huang, Jingchen Zou, Lanxi Meng et al.

Medical image analysis frequently encounters data scarcity challenges. Transfer learning has been effective in addressing this issue while conserving computational resources. The recent advent of foundational models like the DINOv2, which uses the vision transformer architecture, has opened new opportunities in the field and gathered significant interest. However, DINOv2's performance on clinical data still needs to be verified. In this paper, we performed a glioma grading task using three clinical modalities of brain MRI data. We compared the performance of various pre-trained deep learning models, including those based on ImageNet and DINOv2, in a transfer learning context. Our focus was on understanding the impact of the freezing mechanism on performance. We also validated our findings on three other types of public datasets: chest radiography, fundus radiography, and dermoscopy. Our findings indicate that in our clinical dataset, DINOv2's performance was not as strong as ImageNet-based pre-trained models, whereas in public datasets, DINOv2 generally outperformed other models, especially when using the frozen mechanism. Similar performance was observed with various sizes of DINOv2 models across different tasks. In summary, DINOv2 is viable for medical image classification tasks, particularly with data resembling natural images. However, its effectiveness may vary with data that significantly differs from natural images such as MRI. In addition, employing smaller versions of the model can be adequate for medical task, offering resource-saving benefits. Our codes are available at https://github.com/GuanghuiFU/medical_DINOv2_eval.

Han Wang, Jianqiang Li, Qing Zhao et al.

Mental health is a critical global public health issue, and psychological support hotlines play a pivotal role in providing mental health assistance and identifying suicide risks at an early stage. However, the emotional expressions conveyed during these calls remain underexplored in current research. This study introduces a method that combines pitch acoustic features with deep learning-based features to analyze and understand emotions expressed during hotline interactions. Using data from China's largest psychological support hotline, our method achieved an F1-score of 79.13% for negative binary emotion classification.Additionally, the proposed approach was validated on an open dataset for multi-class emotion classification,where it demonstrated better performance compared to the state-of-the-art methods. To explore its clinical relevance, we applied the model to analysis the frequency of negative emotions and the rate of emotional change in the conversation, comparing 46 subjects with suicidal behavior to those without. While the suicidal group exhibited more frequent emotional changes than the non-suicidal group, the difference was not statistically significant.Importantly, our findings suggest that emotional fluctuation intensity and frequency could serve as novel features for psychological assessment scales and suicide risk prediction.The proposed method provides valuable insights into emotional dynamics and has the potential to advance early intervention and improve suicide prevention strategies through integration with clinical tools and assessments The source code is publicly available at https://github.com/Sco-field/Speechemotionrecognition/tree/main.

Zhonglong Chen, Changwei Song, Yining Chen et al.

Suicide and suicidal behaviors remain significant challenges for public policy and healthcare. In response, psychological support hotlines have been established worldwide to provide immediate help to individuals in mental crises. The effectiveness of these hotlines largely depends on accurately identifying callers' emotional states, particularly underlying negative emotions indicative of increased suicide risk. However, the high demand for psychological interventions often results in a shortage of professional operators, highlighting the need for an effective speech emotion recognition model. This model would automatically detect and analyze callers' emotions, facilitating integration into hotline services. Additionally, it would enable large-scale data analysis of psychological support hotline interactions to explore psychological phenomena and behaviors across populations. Our study utilizes data from the Beijing psychological support hotline, the largest suicide hotline in China. We analyzed speech data from 105 callers containing 20,630 segments and categorized them into 11 types of negative emotions. We developed a negative emotion recognition model and a fine-grained multi-label classification model using a large-scale pre-trained model. Our experiments indicate that the negative emotion recognition model achieves a maximum F1-score of 76.96%. However, it shows limited efficacy in the fine-grained multi-label classification task, with the best model achieving only a 41.74% weighted F1-score. We conducted an error analysis for this task, discussed potential future improvements, and considered the clinical application possibilities of our study. All the codes are public available.

Meng Jiang, Yi Jing Yu, Qing Zhao et al.

Cognitive Behavioral Therapy (CBT) is an effective technique for addressing the irrational thoughts stemming from mental illnesses, but it necessitates precise identification of cognitive pathways to be successfully implemented in patient care. In current society, individuals frequently express negative emotions on social media on specific topics, often exhibiting cognitive distortions, including suicidal behaviors in extreme cases. Yet, there is a notable absence of methodologies for analyzing cognitive pathways that could aid psychotherapists in conducting effective interventions online. In this study, we gathered data from social media and established the task of extracting cognitive pathways, annotating the data based on a cognitive theoretical framework. We initially categorized the task of extracting cognitive pathways as a hierarchical text classification with four main categories and nineteen subcategories. Following this, we structured a text summarization task to help psychotherapists quickly grasp the essential information. Our experiments evaluate the performance of deep learning and large language models (LLMs) on these tasks. The results demonstrate that our deep learning method achieved a micro-F1 score of 62.34% in the hierarchical text classification task. Meanwhile, in the text summarization task, GPT-4 attained a Rouge-1 score of 54.92 and a Rouge-2 score of 30.86, surpassing the experimental deep learning model's performance. However, it may suffer from an issue of hallucination. We have made all models and codes publicly available to support further research in this field.

Hongjun Liu, Changwei Song, Jiaqi Qiang et al.

Cushing's syndrome is a condition caused by excessive glucocorticoid secretion from the adrenal cortex, often manifesting with moon facies and plethora, making facial data crucial for diagnosis. Previous studies have used pre-trained convolutional neural networks (CNNs) for diagnosing Cushing's syndrome using frontal facial images. However, CNNs are better at capturing local features, while Cushing's syndrome often presents with global facial features. Transformer-based models like ViT and SWIN, which utilize self-attention mechanisms, can better capture long-range dependencies and global features. Recently, DINOv2, a foundation model based on visual Transformers, has gained interest. This study compares the performance of various pre-trained models, including CNNs, Transformer-based models, and DINOv2, in diagnosing Cushing's syndrome. We also analyze gender bias and the impact of freezing mechanisms on DINOv2. Our results show that Transformer-based models and DINOv2 outperformed CNNs, with ViT achieving the highest F1 score of 85.74%. Both the pre-trained model and DINOv2 had higher accuracy for female samples. DINOv2 also showed improved performance when freezing parameters. In conclusion, Transformer-based models and DINOv2 are effective for Cushing's syndrome classification.