Mete Harun Akcay

Bashir Alam, Masa Cirkovic, Mete Harun Akcay et al.

Imbalanced datasets pose a considerable challenge in training deep learning (DL) models for medical diagnostics, particularly for segmentation tasks. Imbalance may be associated with annotation quality limited annotated datasets, rare cases, or small-scale regions of interest (ROIs). These conditions adversely affect model training and performance, leading to segmentation boundaries which deviate from the true ROIs. Traditional loss functions, such as Binary Cross Entropy, replicate annotation biases and limit model generalization. We propose a novel, statistically driven, conditionally adaptive loss function (CALF) tailored to accommodate the conditions of imbalanced datasets in DL training. It employs a data-driven methodology by estimating imbalance severity using statistical methods of skewness and kurtosis, then applies an appropriate transformation to balance the training dataset while preserving data heterogeneity. This transformative approach integrates a multifaceted process, encompassing preprocessing, dataset filtering, and dynamic loss selection to achieve optimal outcomes. We benchmark our method against conventional loss functions using qualitative and quantitative evaluations. Experiments using large-scale open-source datasets (i.e., UPENN-GBM, UCSF, LGG, and BraTS) validate our approach, demonstrating substantial segmentation improvements. Code availability: https://anonymous.4open.science/r/MICCAI-Submission-43F9/.

Mete Harun Akcay, Buse Gul Atli, Siddharth Prakash Rao et al.

As the volume of stored data continues to grow, identifying and protecting sensitive information within large repositories becomes increasingly challenging, especially when shared with multiple users with different roles and permissions. This work presents a system architecture for trusted data sharing with policy-driven access control, enabling selective protection of sensitive regions while maintaining scalability. The proposed architecture integrates four core modules that combine automated detection of sensitive regions, post-correction, key management, and access control. Sensitive regions are secured using a hybrid scheme that employs symmetric encryption for efficiency and Attribute-Based Encryption for policy enforcement. The system supports efficient key distribution and isolates key storage to strengthen overall security. To demonstrate its applicability, we evaluate the system on visual datasets, where Privacy-Sensitive Objects in images are automatically detected, reassessed, and selectively encrypted prior to sharing in a data repository. Experimental results show that our system provides effective PSO detection, increases macro-averaged F1 score (5%) and mean Average Precision (10%), and maintains an average policy-enforced decryption time of less than 1 second per image. These results demonstrate the effectiveness, efficiency and scalability of our proposed solution for fine-grained access control.