Juhyung Park

Juhyung Park, Dongwon Park, Sooyeon Ji et al.

Deep learning-based denoising methods have shown powerful results for improving the signal-to-noise ratio of magnetic resonance (MR) images, mostly by leveraging supervised learning with clean ground truth. However, acquiring clean ground truth images is often expensive and time-consuming. Self supervised methods have been widely investigated to mitigate the dependency on clean images, but mostly rely on the suboptimal splitting of K-space measurements of an image to yield input and target images for ensuring statistical independence. In this study, we investigate an alternative self-supervised training method for deep denoisers in multi-coil MRI, dubbed Coil2Coil (C2C), that naturally split and combine the multi-coil data among phased array coils, generating two noise-corrupted images for training. This novel approach allows exploiting multi-coil redundancy, but the images are statistically correlated and may not have the same clean image. To mitigate these issues, we propose the methods to pproximately decorrelate the statistical dependence of these images and match the underlying clean images, thus enabling them to be used as the training pairs. For synthetic denoising experiments, C2C yielded the best performance against prior self-supervised methods, reporting outcome comparable even to supervised methods. For real-world denoising cases, C2C yielded consistent performance as synthetic cases, removing only noise structures.

Juhyung Park, Rokgi Hong, Roh-Eul Yoo et al.

Recent advancements in artificial intelligence have created transformative capabilities in image synthesis and generation, enabling diverse research fields to innovate at revolutionary speed and spectrum. In this study, we leverage this generative power to introduce a new paradigm for accelerating Magnetic Resonance Imaging (MRI), introducing a shift from image reconstruction to proactive predictive imaging. Despite being a cornerstone of modern patient care, MRI's lengthy acquisition times limit clinical throughput. Our novel framework addresses this challenge by first predicting a target contrast image, which then serves as a data-driven prior for reconstructing highly under-sampled data. This informative prior is predicted by a generative model conditioned on diverse data sources, such as other contrast images, previously scanned images, acquisition parameters, patient information. We demonstrate this approach with two key applications: (1) reconstructing FLAIR images using predictions from T1w and/or T2w scans, and (2) reconstructing T1w images using predictions from previously acquired T1w scans. The framework was evaluated on internal and multiple public datasets (total 14,921 scans; 1,051,904 slices), including multi-channel k-space data, for a range of high acceleration factors (x4, x8 and x12). The results demonstrate that our prediction-prior reconstruction method significantly outperforms other approaches, including those with alternative or no prior information. Through this framework we introduce a fundamental shift from image reconstruction towards a new paradigm of predictive imaging.

Dongmyung Shin, Younghoon Kim, Chungseok Oh et al.

Carefully engineered radiofrequency (RF) pulses play a key role in a number of systems such as mobile phone, radar, and magnetic resonance imaging. The design of an RF waveform, however, is often posed as an inverse problem with no general solution. As a result, various design methods each with a specific purpose have been developed based on the intuition of human experts. In this work, we propose an artificial intelligence (AI)-powered RF pulse design framework, DeepRF, which utilizes the self-learning characteristics of deep reinforcement learning to generate a novel RF pulse. The effectiveness of DeepRF is demonstrated using four types of RF pulses that are commonly used. The DeepRF-designed pulses successfully satisfy the design criteria while reporting reduced energy. Analyses demonstrate the pulses utilize new mechanisms of magnetization manipulation, suggesting the potentials of DeepRF in discovering unseen design dimensions beyond human intuition. This work may lay the foundation for an emerging field of AI-driven RF waveform design.