5.9CVJun 15, 2023
Out of Distribution Generalization via Interventional Style Transfer in Single-Cell MicroscopyWolfgang M. Pernice, Michael Doron, Alex Quach et al.
Real-world deployment of computer vision systems, including in the discovery processes of biomedical research, requires causal representations that are invariant to contextual nuisances and generalize to new data. Leveraging the internal replicate structure of two novel single-cell fluorescent microscopy datasets, we propose generally applicable tests to assess the extent to which models learn causal representations across increasingly challenging levels of OOD-generalization. We show that despite seemingly strong performance, as assessed by other established metrics, both naive and contemporary baselines designed to ward against confounding, collapse on these tests. We introduce a new method, Interventional Style Transfer (IST), that substantially improves OOD generalization by generating interventional training distributions in which spurious correlations between biological causes and nuisances are mitigated. We publish our code and datasets.
4.1LGDec 1, 2025
Enforcing Orderedness to Improve Feature ConsistencySophie L. Wang, Alex Quach, Nithin Parsan et al.
Sparse autoencoders (SAEs) have been widely used for interpretability of neural networks, but their learned features often vary across seeds and hyperparameter settings. We introduce Ordered Sparse Autoencoders (OSAE), which extend Matryoshka SAEs by (1) establishing a strict ordering of latent features and (2) deterministically using every feature dimension, avoiding the sampling-based approximations of prior nested SAE methods. Theoretically, we show that OSAEs resolve permutation non-identifiability in settings of sparse dictionary learning where solutions are unique (up to natural symmetries). Empirically on Gemma2-2B and Pythia-70M, we show that OSAEs can help improve consistency compared to Matryoshka baselines.
5.7ROOct 16, 2024
Flex: End-to-End Text-Instructed Visual Navigation from Foundation Model FeaturesMakram Chahine, Alex Quach, Alaa Maalouf et al.
End-to-end learning directly maps sensory inputs to actions, creating highly integrated and efficient policies for complex robotics tasks. However, such models often struggle to generalize beyond their training scenarios, limiting adaptability to new environments, tasks, and concepts. In this work, we investigate the minimal data requirements and architectural adaptations necessary to achieve robust closed-loop performance with vision-based control policies under unseen text instructions and visual distribution shifts. Our findings are synthesized in Flex (Fly lexically), a framework that uses pre-trained Vision Language Models (VLMs) as frozen patch-wise feature extractors, generating spatially aware embeddings that integrate semantic and visual information. We demonstrate the effectiveness of this approach on a quadrotor fly-to-target task, where agents trained via behavior cloning on a small simulated dataset successfully generalize to real-world scenes with diverse novel goals and command formulations.