Mahdi Pirayesh Shirazi Nejad

Zequan Liang, Elahe Hosseini, Ning Miao et al.

Continuous oxygen saturation (SpO$_2$) estimation from wearable photoplethysmography (PPG) is important for long-term health monitoring, but low-quality red and infrared PPG segments can distort waveform morphology and degrade SpO$_2$ prediction accuracy. Existing PPG denoising and reconstruction methods usually optimize waveform fidelity or heart rate characteristics, while time-domain waveform loss on PPG signals alone insufficiently preserves frequency structure and SpO$_2$-relevant information. This paper proposes a SpO$_2$ predictor-guided stage-wise time-frequency reconstruction framework for low-quality dual-wavelength PPG signals. The proposed method first selects high-quality PPG segments to pretrain a SpO$_2$ predictor. A masked reconstruction model is then trained to recover randomly masked PPG regions using a joint reconstruction objective that combines time-domain waveform loss with frequency-domain loss computed from the short-time Fourier transform (STFT). To make the reconstruction task physiologically relevant, the pretrained SpO$_2$ predictor is incorporated as an additional constraint, encouraging the reconstructed PPG to preserve SpO$_2$ information rather than only minimizing waveform reconstruction error. The SpO$_2$ predictor and PPG reconstructor model are optimized through four training stages. Experiments on the public OpenOximetry Repository and a private wearable PPG dataset show that the proposed approach achieves the lowest subject-level MAE, with 2.882\% on the public dataset and 2.359\% on the private dataset.

Zequan Liang, Sally Hang, Geneva M. Jost et al.

Galvanic skin response (GSR) is widely used for stress detection, but wrist-based GSR remains challenging because its absolute amplitude can differ substantially from laboratory-grade palmar measurements. In this paper, we propose a unit-independent low-rate wrist GSR processing pipeline to extract the number of skin conductance responses per minute (nSCR/min) as a stress-related feature. We collect paired wrist and palmar GSR recordings from 31 participants during sitting baseline, standing baseline, neutral speaking, and the Trier Social Stress Test (TSST), a laboratory social stressor task. The proposed pipeline cleans the raw GSR signal, decomposes it into tonic skin conductance level (SCL) and phasic skin conductance response (SCR), applies robust z-score normalization, and detects phasic SCR peaks to compute nSCR/min. Using random forest on 25Hz We-Be GSR, nSCR/min achieved balanced accuracies of 0.823 and 0.871 for binary classification between TSST and the sitting and standing baselines, respectively. Moreover, the 25Hz We-Be GSR features achieved comparable balanced accuracy to the original 100Hz features across the evaluated tasks. These results suggest the feasibility of low-rate, unit-independent wrist GSR processing for wearable stress detection.

Farnoush Baghestani, Mahdi Pirayesh Shirazi Nejad, Youngsun Kong et al.

Continuous monitoring of non-invasive skin sympathetic nerve activity (SKNA) holds promise for understanding the sympathetic nervous system (SNS) dynamics in various physiological and pathological conditions. However, muscle noise artifacts present a challenge in accurate SKNA analysis, particularly in real-life scenarios. This study proposes a deep convolutional neural network (CNN) approach to detect and remove muscle noise from SKNA recordings obtained via ECG electrodes. Twelve healthy participants underwent controlled experimental protocols involving cognitive stress induction and voluntary muscle movements, while collecting SKNA data. Power spectral analysis revealed significant muscle noise interference within the SKNA frequency band (500-1000 Hz). A 2D CNN model was trained on the spectrograms of the data segments to classify them into baseline, stress-induced SKNA, and muscle noise-contaminated periods, achieving an average accuracy of 89.85% across all subjects. Our findings underscore the importance of addressing muscle noise for accurate SKNA monitoring, advancing towards wearable SKNA sensors for real-world applications.