Vighnesh Subramaniam

Christopher Wang, Vighnesh Subramaniam, Adam Uri Yaari et al. · harvard, mit

We create a reusable Transformer, BrainBERT, for intracranial recordings bringing modern representation learning approaches to neuroscience. Much like in NLP and speech recognition, this Transformer enables classifying complex concepts, i.e., decoding neural data, with higher accuracy and with much less data by being pretrained in an unsupervised manner on a large corpus of unannotated neural recordings. Our approach generalizes to new subjects with electrodes in new positions and to unrelated tasks showing that the representations robustly disentangle the neural signal. Just like in NLP where one can study language by investigating what a language model learns, this approach opens the door to investigating the brain by what a model of the brain learns. As a first step along this path, we demonstrate a new analysis of the intrinsic dimensionality of the computations in different areas of the brain. To construct these representations, we combine a technique for producing super-resolution spectrograms of neural data with an approach designed for generating contextual representations of audio by masking. In the future, far more concepts will be decodable from neural recordings by using representation learning, potentially unlocking the brain like language models unlocked language.

Vighnesh Subramaniam, Colin Conwell, Boris Katz et al. · mit

A standard assumption in deep learning is that the inductive bias introduced by a neural network architecture must persist from training through inference. The architecture you train with is the architecture you deploy. This assumption constrains the community from selecting architectures that may have desirable efficiency or design properties due to difficulties with optimization. We challenge this assumption with Network of Theseus (NoT), a method for progressively converting a trained, or even untrained, guide network architecture part-by-part into an entirely different target network architecture while preserving the performance of the guide network. At each stage, components in the guide network architecture are incrementally replaced with target architecture modules and aligned via representational similarity metrics. This procedure largely preserves the functionality of the guide network even under substantial architectural changes-for example, converting a convolutional network into a multilayer perceptron, or GPT-2 into a recurrent neural network. By decoupling optimization from deployment, NoT expands the space of viable inference-time architectures, opening opportunities for better accuracy-efficiency tradeoffs and enabling more directed exploration of the architectural design space.

Geeling Chau, Christopher Wang, Sabera Talukder et al.

We present a self-supervised framework that learns population-level codes for arbitrary ensembles of neural recordings at scale. We address key challenges in scaling models with neural time-series data, namely, sparse and variable electrode distribution across subjects and datasets. The Population Transformer (PopT) stacks on top of pretrained temporal embeddings and enhances downstream decoding by enabling learned aggregation of multiple spatially-sparse data channels. The pretrained PopT lowers the amount of data required for downstream decoding experiments, while increasing accuracy, even on held-out subjects and tasks. Compared to end-to-end methods, this approach is computationally lightweight, while achieving similar or better decoding performance. We further show how our framework is generalizable to multiple time-series embeddings and neural data modalities. Beyond decoding, we interpret the pretrained and fine-tuned PopT models to show how they can be used to extract neuroscience insights from large amounts of data. We release our code as well as a pretrained PopT to enable off-the-shelf improvements in multi-channel intracranial data decoding and interpretability. Code is available at https://github.com/czlwang/PopulationTransformer.

Vighnesh Subramaniam, Yilun Du, Joshua B. Tenenbaum et al.

Large language models (LLMs) have achieved remarkable performance in recent years but are fundamentally limited by the underlying training data. To improve models beyond the training data, recent works have explored how LLMs can be used to generate synthetic data for autonomous self-improvement. However, successive steps of self-improvement can reach a point of diminishing returns. In this work, we propose a complementary approach towards self-improvement where finetuning is applied to a multiagent society of language models. A group of language models, all starting from the same base model, are independently specialized by updating each one using data generated through multiagent interactions among the models. By training each model on independent sets of data, we illustrate how this approach enables specialization across models and diversification over the set of models. As a result, our overall system is able to preserve diverse reasoning chains and autonomously improve over many more rounds of fine-tuning than single-agent self-improvement methods. We quantitatively illustrate the efficacy of the approach across a wide suite of reasoning tasks.

Vighnesh Subramaniam, David Mayo, Colin Conwell et al. · mit

We demonstrate that architectures which traditionally are considered to be ill-suited for a task can be trained using inductive biases from another architecture. We call a network untrainable when it overfits, underfits, or converges to poor results even when tuning their hyperparameters. For example, fully connected networks overfit on object recognition while deep convolutional networks without residual connections underfit. The traditional answer is to change the architecture to impose some inductive bias, although the nature of that bias is unknown. We introduce guidance, where a guide network steers a target network using a neural distance function. The target minimizes its task loss plus a layerwise representational similarity against the frozen guide. If the guide is trained, this transfers over the architectural prior and knowledge of the guide to the target. If the guide is untrained, this transfers over only part of the architectural prior of the guide. We show that guidance prevents FCN overfitting on ImageNet, narrows the vanilla RNN-Transformer gap, boosts plain CNNs toward ResNet accuracy, and aids Transformers on RNN-favored tasks. We further identify that guidance-driven initialization alone can mitigate FCN overfitting. Our method provides a mathematical tool to investigate priors and architectures, and in the long term, could automate architecture design.

Vighnesh Subramaniam, Colin Conwell, Christopher Wang et al.

We use (multi)modal deep neural networks (DNNs) to probe for sites of multimodal integration in the human brain by predicting stereoencephalography (SEEG) recordings taken while human subjects watched movies. We operationalize sites of multimodal integration as regions where a multimodal vision-language model predicts recordings better than unimodal language, unimodal vision, or linearly-integrated language-vision models. Our target DNN models span different architectures (e.g., convolutional networks and transformers) and multimodal training techniques (e.g., cross-attention and contrastive learning). As a key enabling step, we first demonstrate that trained vision and language models systematically outperform their randomly initialized counterparts in their ability to predict SEEG signals. We then compare unimodal and multimodal models against one another. Because our target DNN models often have different architectures, number of parameters, and training sets (possibly obscuring those differences attributable to integration), we carry out a controlled comparison of two models (SLIP and SimCLR), which keep all of these attributes the same aside from input modality. Using this approach, we identify a sizable number of neural sites (on average 141 out of 1090 total sites or 12.94%) and brain regions where multimodal integration seems to occur. Additionally, we find that among the variants of multimodal training techniques we assess, CLIP-style training is the best suited for downstream prediction of the neural activity in these sites.