Bita Aslrousta

Kaushal Mhapsekar, Azam Ghanbari, Bita Aslrousta et al.

Cache replacement remains a challenging problem in CPU microarchitecture, often addressed using hand-crafted heuristics, limiting cache performance. Cache data analysis requires parsing millions of trace entries with manual filtering, making the process slow and non-interactive. To address this, we introduce CacheMind, a conversational tool that uses Retrieval-Augmented Generation (RAG) and Large Language Models (LLMs) to enable semantic reasoning over cache traces. Architects can now ask natural language questions like, "Why is the memory access associated with PC X causing more evictions?", and receive trace-grounded, human-readable answers linked to program semantics for the first time. To evaluate CacheMind, we present CacheMindBench, the first verified benchmark suite for LLM-based reasoning for the cache replacement problem. Using the SIEVE retriever, CacheMind achieves 66.67% on 75 unseen trace-grounded questions and 84.80% on 25 unseen policy-specific reasoning tasks; with RANGER, it achieves 89.33% and 64.80% on the same evaluations. Additionally, with RANGER, CacheMind achieves 100% accuracy on 4 out of 6 categories in the trace-grounded tier of CacheMindBench. Compared to LlamaIndex (10% retrieval success), SIEVE achieves 60% and RANGER achieves 90%, demonstrating that existing Retrieval-Augmented Generation (RAGs) are insufficient for precise, trace-grounded microarchitectural reasoning. We provided four concrete actionable insights derived using CacheMind, wherein bypassing use case improved cache hit rate by 7.66% and speedup by 2.04%, software fix use case gives speedup of 76%, and Mockingjay replacement policy use case gives speedup of 0.7%; showing the utility of CacheMind on non-trivial queries that require a natural-language interface.

Shahrzad Jamshidi, Arthur Bousquet, Sugata Banerji et al.

Age prediction using brain imaging, such as MRIs, has achieved promising results, with several studies identifying the model's residual as a potential biomarker for chronic disease states. In this study, we developed a brain age predictive model using a dataset of 1,220 U.S. veterans (18--80 years) and convolutional neural networks (CNNs) trained on two-dimensional slices of axial T2-weighted fast spin-echo and T2-weighted fluid attenuated inversion recovery MRI images. The model, incorporating a degree-3 polynomial ensemble, achieved an $R^{2}$ of 0.816 on the testing set. Images were acquired at the level of the anterior commissure and the frontal horns of the lateral ventricles. Residual analysis was performed to assess its potential as a biomarker for five ICD-coded conditions: hypertension (HTN), diabetes mellitus (DM), mild traumatic brain injury (mTBI), illicit substance abuse/dependence (SAD), and alcohol abuse/dependence (AAD). Residuals grouped by the number of ICD-coded conditions demonstrated different trends that were statistically significant ($p = 0.002$), suggesting a relationship between disease states and predicted brain age. This association was particularly pronounced in patients over 49 years, where negative residuals (indicating advanced brain aging) correlated with the presence of multiple ICD codes. These findings support the potential of residuals as biomarkers for detecting latent health conditions.