Yuyang Jiang

Yuyang Jiang, Chacha Chen, Dang Nguyen et al.

GPT-4V's purported strong multimodal abilities raise interests in using it to automate radiology report writing, but there lacks thorough evaluations. In this work, we perform a systematic evaluation of GPT-4V in generating radiology reports on two chest X-ray report datasets: MIMIC-CXR and IU X-Ray. We attempt to directly generate reports using GPT-4V through different prompting strategies and find that it fails terribly in both lexical metrics and clinical efficacy metrics. To understand the low performance, we decompose the task into two steps: 1) the medical image reasoning step of predicting medical condition labels from images; and 2) the report synthesis step of generating reports from (groundtruth) conditions. We show that GPT-4V's performance in image reasoning is consistently low across different prompts. In fact, the distributions of model-predicted labels remain constant regardless of which groundtruth conditions are present on the image, suggesting that the model is not interpreting chest X-rays meaningfully. Even when given groundtruth conditions in report synthesis, its generated reports are less correct and less natural-sounding than a finetuned LLaMA-2. Altogether, our findings cast doubt on the viability of using GPT-4V in a radiology workflow.

Yuyang Jiang, Chacha Chen, Shengyuan Wang et al. · tsinghua

Existing metrics often lack the granularity and interpretability to capture nuanced clinical differences between candidate and ground-truth radiology reports, resulting in suboptimal evaluation. We introduce a Clinically-grounded tabular framework with Expert-curated labels and Attribute-level comparison for Radiology report evaluation (CLEAR). CLEAR not only examines whether a report can accurately identify the presence or absence of medical conditions, but also assesses whether it can precisely describe each positively identified condition across five key attributes: first occurrence, change, severity, descriptive location, and recommendation. Compared to prior works, CLEAR's multi-dimensional, attribute-level outputs enable a more comprehensive and clinically interpretable evaluation of report quality. Additionally, to measure the clinical alignment of CLEAR, we collaborate with five board-certified radiologists to develop CLEAR-Bench, a dataset of 100 chest X-ray reports from MIMIC-CXR, annotated across 6 curated attributes and 13 CheXpert conditions. Our experiments show that CLEAR achieves high accuracy in extracting clinical attributes and provides automated metrics that are strongly aligned with clinical judgment.

Yuyang Jiang, Longjie Guo, Yuchen Wu et al.

Large language model (LLM)-powered chatbots are increasingly used for opinion exploration. Prior research examined how LLMs alter user views, yet little work extended beyond one-way influence to address how user input can affect LLM responses and how such bi-directional influence manifests throughout the multi-turn conversations. This study investigates this dynamic through 50 controversial-topic discussions with participants (N=266) across three conditions: static statements, standard chatbot, and personalized chatbot. Results show that human opinions barely shifted, while LLM outputs changed more substantially, narrowing the gap between human and LLM stance. Personalization amplified these shifts in both directions compared to the standard setting. Analysis of multi-turn conversations further revealed that exchanges involving participants' personal stories were most likely to trigger stance changes for both humans and LLMs. Our work highlights the risk of over-alignment in human-LLM interaction and the need for careful design of personalized chatbots to more thoughtfully and stably align with users.

Kaixuan Cong, Yifan Wang, Rongkun Xue et al.

Humans do not understand individual events in isolation; rather, they generalize concepts within classes and compare them to others. Existing audio-video pre-training paradigms only focus on the alignment of the overall audio-video modalities, without considering the reinforcement of distinguishing easily confused classes through cognitive induction and contrast during training. This paper proposes the Dynamic Inter-Class Confusion-Aware Encoder (DICCAE), an encoder that aligns audio-video representations at a fine-grained, category-level. DICCAE addresses category confusion by dynamically adjusting the confusion loss based on inter-class confusion degrees, thereby enhancing the model's ability to distinguish between similar activities. To further extend the application of DICCAE, we also introduce a novel training framework that incorporates both audio and video modalities, as well as their fusion. To mitigate the scarcity of audio-video data in the human activity recognition task, we propose a cluster-guided audio-video self-supervised pre-training strategy for DICCAE. DICCAE achieves near state-of-the-art performance on the VGGSound dataset, with a top-1 accuracy of 65.5%. We further evaluate its feature representation quality through extensive ablation studies, validating the necessity of each module.

Rongkun Xue, Jing Yang, Yuyang Jiang et al.

Existing local dynamic route planning algorithms, when directly applied to terrain following/terrain avoidance, or dynamic obstacle avoidance for large and medium-sized fixed-wing aircraft, fail to simultaneously meet the requirements of real-time performance, long-distance planning, and the dynamic constraints of large and medium-sized aircraft. To deal with this issue, this paper proposes the Motion Dynamic RRT based Fluid Field - PPO for dynamic TF/TA routing planning. Firstly, the action and state spaces of the proximal policy gradient algorithm are redesigned using disturbance flow fields and artificial potential field algorithms, establishing an aircraft dynamics model, and designing a state transition process based on this model. Additionally, a reward function is designed to encourage strategies for obstacle avoidance, terrain following, terrain avoidance, and safe flight. Experimental results on real DEM data demonstrate that our algorithm can complete long-distance flight tasks through collision-free trajectory planning that complies with dynamic constraints, without the need for prior global planning.

Chu Qin, Ying Tan, Shang Ying Chen et al.

Unsupervised clustering has broad applications in data stratification, pattern investigation and new discovery beyond existing knowledge. In particular, clustering of bioactive molecules facilitates chemical space mapping, structure-activity studies, and drug discovery. These tasks, conventionally conducted by similarity-based methods, are complicated by data complexity and diversity. We ex-plored the superior learning capability of deep autoencoders for unsupervised clustering of 1.39 mil-lion bioactive molecules into band-clusters in a 3-dimensional latent chemical space. These band-clusters, displayed by a space-navigation simulation software, band molecules of selected bioactivity classes into individual band-clusters possessing unique sets of common sub-structural features beyond structural similarity. These sub-structural features form the frameworks of the literature-reported pharmacophores and privileged fragments. Within each band-cluster, molecules are further banded into selected sub-regions with respect to their bioactivity target, sub-structural features and molecular scaffolds. Our method is potentially applicable for big data clustering tasks of different fields.