Sagi Polaczek

Gal Metzer, Sagi Polaczek, Ali Mahdavi-Amiri et al.

Transformations produced by image and video generation models often evolve in a highly non-linear manner: long stretches where the content barely changes are followed by sudden, abrupt semantic jumps. To analyze and correct this behavior, we introduce a Semantic Progress Function, a one-dimensional representation that captures how the meaning of a given sequence evolves over time. For each frame, we compute distances between semantic embeddings and fit a smooth curve that reflects the cumulative semantic shift across the sequence. Departures of this curve from a straight line reveal uneven semantic pacing. Building on this insight, we propose a semantic linearization procedure that reparameterizes (or retimes) the sequence so that semantic change unfolds at a constant rate, yielding smoother and more coherent transitions. Beyond linearization, our framework provides a model-agnostic foundation for identifying temporal irregularities, comparing semantic pacing across different generators, and steering both generated and real-world video sequences toward arbitrary target pacing.

Sagi Polaczek, Or Patashnik, Ali Mahdavi-Amiri et al.

Editing portrait videos is a challenging task that requires flexible yet precise control over a wide range of modifications, such as appearance changes, expression edits, or the addition of objects. The key difficulty lies in preserving the subject's original temporal behavior, demanding that every edited frame remains precisely synchronized with the corresponding source frame. We present Sync-LoRA, a method for editing portrait videos that achieves high-quality visual modifications while maintaining frame-accurate synchronization and identity consistency. Our approach uses an image-to-video diffusion model, where the edit is defined by modifying the first frame and then propagated to the entire sequence. To enable accurate synchronization, we train an in-context LoRA using paired videos that depict identical motion trajectories but differ in appearance. These pairs are automatically generated and curated through a synchronization-based filtering process that selects only the most temporally aligned examples for training. This training setup teaches the model to combine motion cues from the source video with the visual changes introduced in the edited first frame. Trained on a compact, highly curated set of synchronized human portraits, Sync-LoRA generalizes to unseen identities and diverse edits (e.g., modifying appearance, adding objects, or changing backgrounds), robustly handling variations in pose and expression. Our results demonstrate high visual fidelity and strong temporal coherence, achieving a robust balance between edit fidelity and precise motion preservation.

Yoel Shoshan, Moshiko Raboh, Michal Ozery-Flato et al.

Large language models applied to vast biological datasets have the potential to transform biology by uncovering disease mechanisms and accelerating drug development. However, current models are often siloed, trained separately on small-molecules, proteins, or transcriptomic data, limiting their ability to capture complex, multi-modal interactions. Effective drug discovery requires computational tools that integrate multiple biological entities while supporting prediction and generation, a challenge existing models struggle to address. For this purpose, we present MAMMAL - Molecular Aligned Multi-Modal Architecture and Language - a versatile method applied to create a multi-task foundation model that learns from large-scale biological datasets across diverse modalities, including proteins, small-molecules, and omics. MAMMAL's structured prompt syntax supports classification, regression, and generation tasks while handling token and scalar inputs and outputs. Evaluated on eleven diverse downstream tasks, it reaches a new state of the art (SOTA) in nine tasks and is comparable to SOTA in two tasks, all within a unified architecture, unlike prior task-specific models. Additionally, we explored Alphafold 3 binding prediction capabilities on antibody-antigen and nanobody-antigen complexes showing significantly better classification performance of MAMMAL in 3 out of 4 targets. The model code and pretrained weights are publicly available at https://github.com/BiomedSciAI/biomed-multi-alignment and https://huggingface.co/ibm/biomed.omics.bl.sm.ma-ted-458m

Sagi Polaczek, Yuval Alaluf, Elad Richardson et al.

Vector graphics are essential in design, providing artists with a versatile medium for creating resolution-independent and highly editable visual content. Recent advancements in vision-language and diffusion models have fueled interest in text-to-vector graphics generation. However, existing approaches often suffer from over-parameterized outputs or treat the layered structure - a core feature of vector graphics - as a secondary goal, diminishing their practical use. Recognizing the importance of layered SVG representations, we propose NeuralSVG, an implicit neural representation for generating vector graphics from text prompts. Inspired by Neural Radiance Fields (NeRFs), NeuralSVG encodes the entire scene into the weights of a small MLP network, optimized using Score Distillation Sampling (SDS). To encourage a layered structure in the generated SVG, we introduce a dropout-based regularization technique that strengthens the standalone meaning of each shape. We additionally demonstrate that utilizing a neural representation provides an added benefit of inference-time control, enabling users to dynamically adapt the generated SVG based on user-provided inputs, all with a single learned representation. Through extensive qualitative and quantitative evaluations, we demonstrate that NeuralSVG outperforms existing methods in generating structured and flexible SVG.

Alex Golts, Vadim Ratner, Yoel Shoshan et al.

Bioactivity data plays a key role in drug discovery and repurposing. The resource-demanding nature of \textit{in vitro} and \textit{in vivo} experiments, as well as the recent advances in data-driven computational biochemistry research, highlight the importance of \textit{in silico} drug target interaction (DTI) prediction approaches. While numerous large public bioactivity data sources exist, research in the field could benefit from better standardization of existing data resources. At present, different research works that share similar goals are often difficult to compare properly because of different choices of data sources and train/validation/test split strategies. Additionally, many works are based on small data subsets, leading to results and insights of possible limited validity. In this paper we propose a way to standardize and represent efficiently a very large dataset curated from multiple public sources, split the data into train, validation and test sets based on different meaningful strategies, and provide a concrete evaluation protocol to accomplish a benchmark. We analyze the proposed data curation, prove its usefulness and validate the proposed benchmark through experimental studies based on an existing neural network model.