Yineng Chen

Yineng Chen, Zuchao Li, Lefei Zhang et al.

Optimizer is an essential component for the success of deep learning, which guides the neural network to update the parameters according to the loss on the training set. SGD and Adam are two classical and effective optimizers on which researchers have proposed many variants, such as SGDM and RAdam. In this paper, we innovatively combine the backward-looking and forward-looking aspects of the optimizer algorithm and propose a novel \textsc{Admeta} (\textbf{A} \textbf{D}ouble exponential \textbf{M}oving averag\textbf{E} \textbf{T}o \textbf{A}daptive and non-adaptive momentum) optimizer framework. For backward-looking part, we propose a DEMA variant scheme, which is motivated by a metric in the stock market, to replace the common exponential moving average scheme. While in the forward-looking part, we present a dynamic lookahead strategy which asymptotically approaches a set value, maintaining its speed at early stage and high convergence performance at final stage. Based on this idea, we provide two optimizer implementations, \textsc{AdmetaR} and \textsc{AdmetaS}, the former based on RAdam and the latter based on SGDM. Through extensive experiments on diverse tasks, we find that the proposed \textsc{Admeta} optimizer outperforms our base optimizers and shows advantages over recently proposed competitive optimizers. We also provide theoretical proof of these two algorithms, which verifies the convergence of our proposed \textsc{Admeta}.

Ting Yu Tsai, Liangqiao Gui, Yineng Chen et al.

Deep learning models have achieved significant success in segmenting cardiovascular structures, but there is a growing need to improve their generalization and robustness. Current methods often face challenges such as overfitting and limited accuracy, largely due to their reliance on large annotated datasets and limited optimization techniques. This paper introduces the UU-Mamba model, an extension of the U-Mamba architecture, designed to address these challenges in both cardiac and vascular segmentation. By incorporating Sharpness-Aware Minimization (SAM), the model enhances generalization by seeking flatter minima in the loss landscape. Additionally, we propose an uncertainty-aware loss function that integrates region-based, distribution-based, and pixel-based components, improving segmentation accuracy by capturing both local and global features. We expand our evaluations on the ImageCAS (coronary artery) and Aorta (aortic branches and zones) datasets, which present more complex segmentation challenges than the ACDC dataset (left and right ventricles) used in prior work, showcasing the model's adaptability and resilience. Our results confirm UU-Mamba's superior performance compared to leading models such as TransUNet, Swin-Unet, nnUNet, and nnFormer. We also provide a more in-depth assessment of the model's robustness and segmentation accuracy through extensive experiments.

Peng Huang, Yiming Wang, Yineng Chen et al.

Echocardiography plays an important role in the screening and diagnosis of cardiovascular diseases. However, automated intelligent analysis of echocardiographic data remains challenging due to complex cardiac dynamics and strong view heterogeneity. In recent years, visual language models (VLM) have opened a new avenue for building ultrasound understanding systems for clinical decision support. Nevertheless, most existing methods formulate this task as a direct mapping from video and question to answer, making them vulnerable to template shortcuts and spurious explanations. To address these issues, we propose EchoTrust, an evidence-driven Actor-Verifier framework for trustworthy reasoning in echocardiography VLM-based agents. EchoTrust produces a structured intermediate representation that is subsequently analyzed by distinct roles, enabling more reliable and interpretable decision-making for high-stakes clinical applications.

Frank Cole, Dixi Wang, Yineng Chen et al.

We introduce \emph{in-context operator learning on probability measure spaces} for optimal transport (OT). The goal is to learn a single solution operator that maps a pair of distributions to the OT map, using only few-shot samples from each distribution as a prompt and \emph{without} gradient updates at inference. We parameterize the solution operator and develop scaling-law theory in two regimes. In the \emph{nonparametric} setting, when tasks concentrate on a low-intrinsic-dimension manifold of source--target pairs, we establish generalization bounds that quantify how in-context accuracy scales with prompt size, intrinsic task dimension, and model capacity. In the \emph{parametric} setting (e.g., Gaussian families), we give an explicit architecture that recovers the exact OT map in context and provide finite-sample excess-risk bounds. Our numerical experiments on synthetic transports and generative-modeling benchmarks validate the framework.

Hang Yang, Hao Chen, Hui Guo et al.

Accurate and efficient question-answering systems are essential for delivering high-quality patient care in the medical field. While Large Language Models (LLMs) have made remarkable strides across various domains, they continue to face significant challenges in medical question answering, particularly in understanding domain-specific terminologies and performing complex reasoning. These limitations undermine their effectiveness in critical medical applications. To address these issues, we propose a novel approach incorporating similar case generation within a multi-agent medical question-answering (MedQA) system. Specifically, we leverage the Llama3.1:70B model, a state-of-the-art LLM, in a multi-agent architecture to enhance performance on the MedQA dataset using zero-shot learning. Our method capitalizes on the model's inherent medical knowledge and reasoning capabilities, eliminating the need for additional training data. Experimental results show substantial performance gains over existing benchmark models, with improvements of 7% in both accuracy and F1-score across various medical QA tasks. Furthermore, we examine the model's interpretability and reliability in addressing complex medical queries. This research not only offers a robust solution for medical question answering but also establishes a foundation for broader applications of LLMs in the medical domain.

Xin Wang, Yineng Chen, Shu Hu et al.

Neural Radiance Fields (NeRF), as a pioneering technique in computer vision, offer great potential to revolutionize medical imaging by synthesizing three-dimensional representations from the projected two-dimensional image data. However, they face unique challenges when applied to medical applications. This paper presents a comprehensive examination of applications of NeRFs in medical imaging, highlighting four imminent challenges, including fundamental imaging principles, inner structure requirement, object boundary definition, and color density significance. We discuss current methods on different organs and discuss related limitations. We also review several datasets and evaluation metrics and propose several promising directions for future research.

Yineng Chen, Peng Huang, Aozhong Zhang et al.

Foundation models have achieved remarkable results in medical image analysis. However, its large network architecture and high computational complexity significantly impact inference speed, limiting its application on terminal medical devices. Quantization, a technique that compresses models into low-bit versions, is a solution to this challenge. In this paper, we propose a post-training quantization algorithm, Permutation-COMQ. It eliminates the need for backpropagation by using simple dot products and rounding operations, thereby removing hyperparameter tuning and simplifying the process. Additionally, we introduce a weight-aware strategy that reorders the weight within each layer to address the accuracy degradation induced by channel-wise scaling during quantization, while preserving channel structure. Experiments demonstrate that our method achieves the best results in 2-bit, 4-bit, and 8-bit quantization.

Yuchen Zou, Yineng Chen, Zuchao Li et al.

Transformer, a deep neural network architecture, has long dominated the field of natural language processing and beyond. Nevertheless, the recent introduction of Mamba challenges its supremacy, sparks considerable interest among researchers, and gives rise to a series of Mamba-based models that have exhibited notable potential. This survey paper orchestrates a comprehensive discussion, diving into essential research dimensions, covering: (i) the functioning of the Mamba mechanism and its foundation on the principles of structured state space models; (ii) the proposed improvements and the integration of Mamba with various networks, exploring its potential as a substitute for Transformers; (iii) the combination of Transformers and Mamba to compensate for each other's shortcomings. We have also made efforts to interpret Mamba and Transformer in the framework of kernel functions, allowing for a comparison of their mathematical nature within a unified context. Our paper encompasses the vast majority of improvements related to Mamba to date.