Fouzi Harrou

Wu Wang, Yuang Cheng, Fouzi Harrou et al.

Early and reliable detection of Alzheimer's disease (AD) is crucial for timely clinical intervention and improved patient management. It also supports the evaluation of emerging therapeutic strategies. In this paper, we propose a Low-Rank Mixture of Experts (LoRA-MoE) deep learning framework for Alzheimer's disease diagnosis based on handwriting analysis. Handwriting signals provide a non-invasive and scalable digital biomarker that captures subtle cognitive-motor impairments associated with early AD progression. The proposed architecture allows multiple experts to specialize in different handwriting patterns while sharing a common base network. This design enables efficient learning of general representations while reducing interference between experts. Each expert is equipped with lightweight low-rank adapters. This mechanism significantly reduces the number of trainable parameters compared with standard Mixture of Experts (MoE) models and improves training stability. The proposed framework is evaluated on the Diagnosis AlzheimeR WIth haNdwriting (DARWIN) dataset. Extensive experiments are conducted, including ablation studies on key architectural parameters such as hidden dimension size, number of experts, and LoRA rank. The method is compared with multilayer perceptron (MLP) and conventional MoE architectures. In addition, stacking ensemble strategies (StackMean and StackMax) are investigated to improve robustness and predictive performance. Experimental results show that the LoRA-MoE framework achieves powerful diagnostic performance while activating significantly fewer parameters during inference. These results highlight the potential of the proposed approach as an accurate and computationally efficient solution for handwriting-based Alzheimer's disease screening and digital health applications.

Zuzheng Wang, Fouzi Harrou, Ying Sun et al.

Detecting anomalies in crowded video scenes is critical for public safety, enabling timely identification of potential threats. This study explores video anomaly detection within a Functional Data Analysis framework, focusing on the application of the Magnitude-Shape (MS) Plot. Autoencoders are used to learn and reconstruct normal behavioral patterns from anomaly-free training data, resulting in low reconstruction errors for normal frames and higher errors for frames with potential anomalies. The reconstruction error matrix for each frame is treated as multivariate functional data, with the MS-Plot applied to analyze both magnitude and shape deviations, enhancing the accuracy of anomaly detection. Using its capacity to evaluate the magnitude and shape of deviations, the MS-Plot offers a statistically principled and interpretable framework for anomaly detection. The proposed methodology is evaluated on two widely used benchmark datasets, UCSD Ped2 and CUHK Avenue, demonstrating promising performance. It performs better than traditional univariate functional detectors (e.g., FBPlot, TVDMSS, Extremal Depth, and Outliergram) and several state-of-the-art methods. These results highlight the potential of the MS-Plot-based framework for effective anomaly detection in crowded video scenes.

Fatiha Hamdi, Abdelhafid Zeroual, Fouzi Harrou

Hybrid physical systems combine continuous and discrete dynamics, which can be simultaneously affected by faults. Conventional fault detection methods often treat these dynamics separately, limiting their ability to capture interacting fault patterns. This paper proposes a unified fault detection framework for hybrid dynamical systems by integrating an Extended Timed Continuous Petri Net (ETCPN) model with semi-supervised anomaly detection. The proposed ETCPN extends existing Petri net formalisms by introducing marking-dependent flow functions, enabling intrinsic coupling between discrete and continuous dynamics. Based on this structure, a mode-dependent hybrid observer is designed, whose stability under arbitrary switching is ensured via Linear Matrix Inequalities (LMIs), solved offline to determine observer gains. The observer generates residuals that reflect discrepancies between the estimated and measured outputs. These residuals are processed using semi-supervised methods, including One-Class SVM (OC-SVM), Support Vector Data Description (SVDD), and Elliptic Envelope (EE), trained exclusively on normal data to avoid reliance on labeled faults. The framework is validated through simulations involving discrete faults, continuous faults, and hybrid faults. Results demonstrate high detection accuracy, fast convergence, and robust performance, with OC-SVM and SVDD providing the best trade-off between detection rate and false alarms. The framework is computationally efficient for real-time deployment, as the main complexity is confined to the offline LMI design phase.